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Research shows that treatment with nitric oxide after storage may dramatically improve the viability of transplanted livers

About 5,000 liver transplants are performed annually in the United States, and a key factor ensuring success is maintaining a healthy donor organ that can function effectively in the recipient. However, transplanted livers typically incur substantial damage when blood flow is restored to the organ after the transplant.

24 May 2004

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Researchers in the department of ophthalmology at the University of Arizona College of Medicine in Tucson played an important role in the development of Restasis, the first alternative to artificial tears for the treatment of dry eye syndrome.

21 May 2004

WHO reports likely Ebola case in Sudan

As of 10 May, WHO reported cases of Ebola haemorrhagic fever syndrome in Hai-Cuba, Yambio, Western Equatoria Region, south Sudan. A rapid assessment team is in the field to investigate the situation. Clinical samples have been collected and preliminary results are expected soon.

21 May 2004

Obese women more likely to have pregnancy complications and caesarean sections than women of average weight

The controlled study is one of the largest ever to look at obesity in pregnancy, following more than 16,000 pregnant women at 14 medical centers across the country.

20 May 2004

Causes of hepatitis and potential therapies that may improve care presented in study

Hepatitis, a potentially serious disease caused by a virus that attacks the liver, is a major problem worldwide. Hepatitis A is generally food-borne, while hepatitis B and C spread primarily through parenteral or sexual routes. Hepatitis B and C can be life-long, potentially deadly chronic infections.

19 May 2004

Caffeinated beverages may benefit some people who are at high-risk for liver disease

According to new research presented today at Digestive Disease Week, drinking caffeinated beverages may benefit some people who are at high-risk for liver disease. Conversely, a study by researchers from India found that soda drinkers, who represent a huge percentage of the American population, may actually have an increased risk of developing esophageal cancer.

19 May 2004

Fatty liver disease (NAFLD) in obese children has distinct characteristics different from those found in adults

Potentially life-threatening non-alcoholic fatty liver disease (NAFLD) in obese children has distinct characteristics, often different from those found in adults, according to a University of California, San Diego (UCSD) School of Medicine study led by Jeffrey Schwimmer, M.D., assistant professor of pediatrics.

19 May 2004

Benitec acquires Avocel to focus on rapid development of hepatitis C therapeutics

Benitec Ltd. today announced the acquisition of Avocel, Inc. of Sunnyvale, CA, a leading RNAi therapeutics company, and the establishment of its wholly-owned US subsidiary, Benitec, Inc. Through the acquisition, Benitec gains its first in-house advanced therapeutic development program using DNA-directed RNAi (ddRNAi) to target the Hepatitis C virus.

18 May 2004

Interventional radiologists now are able to treat using minimally invasive procedures

Interventional radiologists at Temple University Hospital now are able to treat many patients with minimally invasive procedures not available only a few years ago. “Conditions that used to require extensive surgery now take an hour or less, and patients leave with a bandaid and walk home,” says Gary Cohen, M.D., Section Chief of Interventional Radiology and Vice Chairman of Radiology. “How can you beat that?”

17 May 2004

Regional review boards improve liver transplant allocation

The United Network for Organ Sharing (UNOS) currently utilizes scores based on the Model for End-Stage Liver Disease (MELD) or Pediatric End-Stage Liver Disease (PELD) to prioritize patients waiting for liver transplants.

17 May 2004

Researcher has learned how to maximize the cancer-fighting power of broccoli

University of Illinois researcher Elizabeth Jeffery has learned how to maximize the cancer-fighting power of broccoli. It involves heating broccoli just enough to eliminate a sulfur-grabbing protein, but not enough to stop the plant from releasing an important cancer-fighting compound called sulforaphane.

15 May 2004

Risk of artery plaques increased by use of HIV drugs

An Italian study has provided evidence that HIV drugs called protease inhibitors may increase the risk of artery "plaques."

15 May 2004

Signs of liver disease also improve in conjunction with alterations to gut flora

Some cirrhotic patients develop brain dysfunction, called hepatic encephalopathy, which causes deficits in behavior, intelligence, consciousness and neuromuscular function.

14 May 2004

Screening for liver diseases benefits outweigh costs for some, but not all, conditions

Screening programs for liver diseases can detect asymptomatic conditions which might have better outcomes if diagnosed and treated earlier.

14 May 2004

Largest study comparing leading hepatitis C treatments

Medical centers, hospitals, clinics and other treatment sites across the country are actively enrolling Americans with the hepatitis C virus (HCV) in a nationwide study that will for the first time determine which of the two FDA-approved pegylated interferon therapy regimens offers patients the best chance to eliminate the virus.

14 May 2004

Suprachiasmatic nucleus brain tissue sheds light on jet lag

New research led by a University of Washington biologist demonstrates that there are at least two circadian clocks in the mammal brain, one that sticks strictly to an internal schedule and another that can be altered by external influences such as light and dark.

12 May 2004

Compound found in the peels of citrus fruit can potentially lower cholesterol more effectively than prescription drugs

A compound found in the peels of citrus fruit has the potential to lower cholesterol more effectively than some prescription drugs, and without side effects, according to a study by U.S. and Canadian researchers.

11 May 2004

Risk of prostate cancer greater in men over 50 with high levels of testosterone

Men over 50 years of age with high blood levels of testosterone have an increased risk of prostate cancer, according to a study by researchers at Johns Hopkins and the National Institute on Aging. The finding throws some doubt on the safety of testosterone replacement therapy, the investigators say.

11 May 2004

Strategy to treat obesity through molecular liposuction

Researchers at The University of Texas M. D. Anderson Cancer Center have designed a strategy to treat obesity through “molecular liposuction.” The therapy destroys blood vessels supporting fat accumulation — causing the fat to rapidly break down and disappear.

10 May 2004

Genetic breakthrough in tracing the cause of a rare kidney and liver disorder

Birmingham scientists have made a genetic breakthrough in tracing the cause of a rare kidney and liver disorder. ARC syndrome means babies are born with impairment to kidney and liver function, bleeding problems and weak muscles. This usually leads to early death. The gene which causes this condition has been identified.

8 May 2004

Liver News and Research

Research shows that treatment with nitric oxide after storage may dramatically improve the viability of transplanted livers

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

WHO reports likely Ebola case in Sudan

Obese women more likely to have pregnancy complications and caesarean sections than women of average weight

Causes of hepatitis and potential therapies that may improve care presented in study

Caffeinated beverages may benefit some people who are at high-risk for liver disease

Fatty liver disease (NAFLD) in obese children has distinct characteristics different from those found in adults

Benitec acquires Avocel to focus on rapid development of hepatitis C therapeutics

Interventional radiologists now are able to treat using minimally invasive procedures

Regional review boards improve liver transplant allocation

Researcher has learned how to maximize the cancer-fighting power of broccoli

Risk of artery plaques increased by use of HIV drugs

Signs of liver disease also improve in conjunction with alterations to gut flora

Screening for liver diseases benefits outweigh costs for some, but not all, conditions

Largest study comparing leading hepatitis C treatments

Suprachiasmatic nucleus brain tissue sheds light on jet lag

Compound found in the peels of citrus fruit can potentially lower cholesterol more effectively than prescription drugs

Risk of prostate cancer greater in men over 50 with high levels of testosterone

Strategy to treat obesity through molecular liposuction

Genetic breakthrough in tracing the cause of a rare kidney and liver disorder

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