Laboratory News and Research

RSS

Clinical study shows new mechanism that BCG vaccine uses to reverse advanced type 1 diabetes

Interim results from a FDA-approved clinical trial testing the generic vaccine bacillus Calmette-Guérin (BCG) to reverse advanced type 1 diabetes are being presented at the 75th Scientific Sessions of the American Diabetes Association.

12 Jun 2017

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab.

9 Jun 2017

Joslin Diabetes Center researchers establish CCTD to develop and translate cell-based interventions

Researchers and clinicians at Joslin Diabetes Center have established a Center for Cell-Based Therapy for Diabetes, the goal of which is to lead the development and translation of cell-based interventions to treat and cure diabetes and its complications.

9 Jun 2017

Radiation therapy critical to treating brain tumors, but linked to significant adverse effects

Radiation therapy using high-energy particles, like x-rays or electron beams, is a common and critical component in successfully treating patients with brain tumors, but it is also associated with significant adverse effects, such as neuronal loss in adjacent healthy tissues.

9 Jun 2017

Researchers study space-exposed worms to improve understanding of regenerative health

Flatworms that spent five weeks aboard the International Space Station are helping researchers led by Tufts University scientists to study how an absence of normal gravity and geomagnetic fields can have anatomical, behavioral, and bacteriological consequences, according to a paper to be published June 13 in Regeneration.

9 Jun 2017

Scientists find way to recover protein structure after chemical denaturation

Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation.

9 Jun 2017

Zika virus infection during pregnancy causes birth defects in 5% of babies, study finds

According to a report published today in the Morbidity and Mortality Weekly Report of Centers for Disease Control and Prevention (CDC), 5% of women in the U.S. and its territories who had confirmed Zika virus infection during pregnancy had a baby or fetus with Zika virus-associated birth defects.

9 Jun 2017

Without Measurement, There is No Control of Aseptic Processes

An interview with Gilberto Dalmaso, discussing the different grades of pharmaceutical cleanrooms and the production of high level compounds under aseptic conditions.

From Particle Measuring Systems 9 Jun 2017

UNC researchers identify how class of antiviral drugs interacts with HCV

Globally, an estimated 71 million people are living with chronic hepatitis C virus (HCV). Over decades of infection, chronic HCV infection results in progressive damage to the liver and an increased risk for end stage liver disease and liver cancer, making the virus the leading cause of liver-related deaths in the United States today.

9 Jun 2017

Salk researchers analyze how neurons in the brain respond to natural scenes

If you think self-driving cars can't get here soon enough, you're not alone. But programming computers to recognize objects is very technically challenging, especially since scientists don't fully understand how our own brains do it.

9 Jun 2017

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells' defensive properties while switching on a robust anticancer immune response in mice.

8 Jun 2017

New florescent imaging technique tracks actions of key enzymes in cancer, kidney disease

Researchers at the Universities of York and Leiden have pioneered a technique which uses florescent imaging to track the actions of key enzymes in cancer, genetic disorders and kidney disease.

8 Jun 2017

Rice scientists use magnets and nanoparticles to make vessels temporarily ‘leaky’

The endothelial cells that line blood vessels are packed tightly to keep blood inside and flowing, but scientists at Rice University and their colleagues have discovered it may be possible to selectively open gaps in those barriers just enough to let large molecules through -- and then close them again.

8 Jun 2017

More-is-better approach appears to improve vaccine protection from HIV-like virus in monkeys

Building on insights from an HIV vaccine regimen in humans that had partial success during a phase 3 clinical trial in Thailand, a Duke-led research team used a more-is-better approach in monkeys that appeared to improve vaccine protection from an HIV-like virus.

8 Jun 2017

Research reveals link between POMC neurons and release of insulin by the pancreas

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses.

8 Jun 2017

Researchers explore sea urchin protein to understand self-assembly of skeletal structures

Calcium carbonate, or CaCO3, comprises more than 4% of the earth's crust. Its most common natural forms are chalk, limestone, and marble, produced by the sedimentation of the shells of small fossilized snails, shellfish, and coral over millions of years.

8 Jun 2017

Salk scientist uses mathematical framework to better understand how cell types divide work

Despite advances in neuroscience, the brain is still very much a black box--no one even knows how many different types of neurons exist.

7 Jun 2017

Two-pronged algorithm may prove to be accurate tool for predicting response to checkpoint inhibitors

The class of immunotherapies known as checkpoint inhibitors have proven to be a highly effective and advantageous treatment option for many cancer patients, but they don't work well for everyone, and oncologists have no reliable way to determine in advance which patients are likely to respond to these drugs.

7 Jun 2017

Molecular biologists identify enzyme that activates and ‘supercharges’ cellular machinery

St. Jude Children's Research Hospital molecular biologists have identified an enzyme that activates and "supercharges" cellular machinery that controls how cells become specialized cells in the body.

7 Jun 2017

Researchers uncover novel and non-invasive way to track dengue infection

Commonly used to detect solid tumors, positron emission tomography (PET) paired with the glucose metabolism probe, fluorodeoxyglucose (FDG), is considered 'old' technology in the field of cancer.

6 Jun 2017

Laboratory News and Research

Clinical study shows new mechanism that BCG vaccine uses to reverse advanced type 1 diabetes

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

Joslin Diabetes Center researchers establish CCTD to develop and translate cell-based interventions

Radiation therapy critical to treating brain tumors, but linked to significant adverse effects

Researchers study space-exposed worms to improve understanding of regenerative health

Scientists find way to recover protein structure after chemical denaturation

Zika virus infection during pregnancy causes birth defects in 5% of babies, study finds

Without Measurement, There is No Control of Aseptic Processes

UNC researchers identify how class of antiviral drugs interacts with HCV

Salk researchers analyze how neurons in the brain respond to natural scenes

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

New florescent imaging technique tracks actions of key enzymes in cancer, kidney disease

Rice scientists use magnets and nanoparticles to make vessels temporarily ‘leaky’

More-is-better approach appears to improve vaccine protection from HIV-like virus in monkeys

Research reveals link between POMC neurons and release of insulin by the pancreas

Researchers explore sea urchin protein to understand self-assembly of skeletal structures

Salk scientist uses mathematical framework to better understand how cell types divide work

Two-pronged algorithm may prove to be accurate tool for predicting response to checkpoint inhibitors

Molecular biologists identify enzyme that activates and ‘supercharges’ cellular machinery

Researchers uncover novel and non-invasive way to track dengue infection

Pittcon 2024 - Advancing Science on the West Coast eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Latest Life Science News