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Researchers develop game-changing diagnostic and prognostic genetic tests for prostate cancer

Researchers at the Kimmel Cancer Center at Jefferson (KCC) have developed potentially game-changing diagnostic and prognostic genetic tests shown to better predict prostate cancer survival outcomes and distinguish clinically-relevant cancers.

21 Dec 2012

Combination of diet and exercise may prevent breast cancer in obese, postmenopausal women

Obese, postmenopausal women are at greater risk for developing breast cancer and their cancers tend to be more aggressive than those in lean counterparts.

20 Dec 2012

Slushy spares kidney during partial nephrectomy

US researchers report the success and feasibility of a novel method of carrying out partial nephrectomy in kidney patients, using minimally invasive surgery.

20 Dec 2012

Patients with hypertension or diabetes have increased risk of cancer recurrence, survival

By all accounts, a combination of colon cancer, diabetes and high blood pressure can be a recipe for medical disaster. Now, a new study led by a surgical oncologist and researcher at Temple University School of Medicine and Fox Chase Cancer Center has shown just how deadly this mix can be.

20 Dec 2012

Investigators report non-coding miRNAs as appealing biomarkers for cancer malignancy

As many as 50 percent of all human protein-coding genes are regulated by microRNA (miRNA) molecules. While some miRNAs impact onset and progression of cancer, others can actually suppress the development of malignant tumors and are useful in cancer therapy. They can also serve as potential biomarkers for early cancer detection. In a new issue of Cancer Biomarkers, investigators report on non-coding miRNAs as appealing biomarkers for malignancy.

20 Dec 2012

Personalized rectal cancer therapy shows promise

Personalized chemotherapy for rectal cancer results in high rates of pathologic response, indicate the results of a pilot study.

19 Dec 2012

Health care quality: Hospital readmission rates, innovations in patient care

Modern Healthcare reports on new research that raises questions about the relationship between shorter hospital stays and higher hospital readmission rates.

19 Dec 2012

Tumor cells manipulate unfolded protein response

Researchers at the University of California, San Diego School of Medicine report that tumor cells use stress signals to subvert responding immune cells, exploiting them to actually boost conditions beneficial to cancer growth.

19 Dec 2012

Targeting km23-1 protein may slow the spread of cancer cells

The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine.

19 Dec 2012

Budding yeast an acceptable model system to study KP1019 anti-cancer drug

Researchers have found that the budding yeast (Saccharomyces cerevisiae) is an acceptable model system to study KP1019, an anti-cancer drug that uses ruthenium, a rare metal, a new study found. Researchers had previously been interested in studying KP1019 because it is believed to cause cancer cell death and is not known to have negative secondary side effects for healthy tissues.

19 Dec 2012

Scientists decode VEGF/Ang1/Syx pathway that regulates leakiness of blood vessels

A research team led by scientists at Mayo Clinic in Florida have decoded the entire pathway that regulates leakiness of blood vessels — a condition that promotes a wide number of disorders, such as heart disease, cancer growth and spread, inflammation and respiratory distress.

18 Dec 2012

BubR1 and its associated regulators promising targets for aging disorders and cancer

A new series of studies in mouse models by Mayo Clinic researchers uncovered that the aging process is characterized by high rates of whole-chromosome losses and gains in various organs, including heart, muscle, kidney and eye, and demonstrate that reducing these rates slows age-related tissue deterioration and promotes a healthier life span. The findings appear in today's online issue of Nature Cell Biology.

18 Dec 2012

MiR-181 molecule tied to breast cancer metastasis

Researchers at Case Western Reserve University School of Medicine have identified a molecule linked to more aggressive forms of breast cancer - a discovery that could point the way to potential cures.

18 Dec 2012

Advanced MRI can non-invasively evaluate cellular proliferation of tumor models of breast cancer

Scientists at the University of Arizona Cancer Center and the Moffitt Cancer Center, led by Dr. Robert Gillies, have demonstrated that an advanced magnetic resonance imaging (MRI) method can non-invasively evaluate the cellular proliferation of tumor models of breast cancer.

18 Dec 2012

Vero system can treat patients with recent diagnoses of metastatic cancer

University of Florida radiation oncologists are using a sophisticated medical device to treat patients who have recent diagnoses of metastatic cancer, where the disease has started to spread from one part of the body to another.

18 Dec 2012

New MIT technology may help make cancer biomarker detection much easier

Finding ways to diagnose cancer earlier could greatly improve the chances of survival for many patients. One way to do this is to look for specific proteins secreted by cancer cells, which circulate in the bloodstream. However, the quantity of these biomarkers is so low that detecting them has proven difficult.

17 Dec 2012

Tumor News and Research

Researchers develop game-changing diagnostic and prognostic genetic tests for prostate cancer

Combination of diet and exercise may prevent breast cancer in obese, postmenopausal women

Slushy spares kidney during partial nephrectomy

Patients with hypertension or diabetes have increased risk of cancer recurrence, survival

Investigators report non-coding miRNAs as appealing biomarkers for cancer malignancy

Personalized rectal cancer therapy shows promise

Health care quality: Hospital readmission rates, innovations in patient care

Tumor cells manipulate unfolded protein response

Targeting km23-1 protein may slow the spread of cancer cells

Budding yeast an acceptable model system to study KP1019 anti-cancer drug

Scientists decode VEGF/Ang1/Syx pathway that regulates leakiness of blood vessels

BubR1 and its associated regulators promising targets for aging disorders and cancer

MiR-181 molecule tied to breast cancer metastasis

Advanced MRI can non-invasively evaluate cellular proliferation of tumor models of breast cancer

Vero system can treat patients with recent diagnoses of metastatic cancer

New MIT technology may help make cancer biomarker detection much easier

Nephron-sparing surgery beats ablation for small renal masses

Preop features predict pathology of small renal masses

Lapatinib benefits found for HER2-positive early-stage patients

Study reveals how BRCA1 enzymatic activity may stop cancer cell growth

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