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New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

High bitter-taste sensitivity linked to increased risk of cancer

High bitter-taste sensitivity is associated with a significantly increased risk of cancer in older British women, according to researchers who conducted a unique study of 5,500 women whose diet, lifestyle and health has been tracked for about 20 years.

18 Jul 2018

Researchers identify new potential target protein for colon cancer

Researchers at Boston University School of Medicine have identified a new potential target protein they believe can help further the understanding of colon cancer and ultimately survival of patients with the disease.

18 Jul 2018

Improved methods to measure enterococci concentrations in recreational water

The concentration of enterococci, bacteria that thrive in feces, has long been the federal standard for determining water quality.

16 Jul 2018

3D modeling of drug resistance could lead to more effective cancer treatment

The National Institutes of Health is funding the research of a University of Akron scientist that could lead to more effective cancer treatment.

16 Jul 2018

Mailing colorectal cancer tests to patients increases screening rates, report researchers

Mailing colorectal cancer screening tests to patients insured by Medicaid increased screening rates for this population, report researchers at the University of North Carolina Comprehensive Cancer Center.

16 Jul 2018

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

In an article published recently in the journal Nature Communications, researchers affiliated with the University of São Paulo in Brazil describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease.

16 Jul 2018

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

A review of more than 200 studies reveals that olfactory receptors--proteins that bind to odors that aid the sense of smell--perform a wide range of mostly unknown functions outside the nose.

12 Jul 2018

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine.

12 Jul 2018

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets

11 Jul 2018

Geography may be destiny in end-of-life care for cancer patients

When it comes to how much end-of-life care a patient with cancer receives, geography may, indeed, be destiny, according to new research led by Harvard Medical School that found striking differences in terminal care across different parts of the country.

10 Jul 2018

Younger rectal cancer patients do not experience survival benefit from currently recommended therapies

A new study reveals that individuals younger than 50 years of age who are diagnosed with rectal cancer do not experience an overall survival benefit from currently recommended treatments.

9 Jul 2018

Research elucidates maturation of cancer-causing miRNAs

An international research team led by Helmholtz Zentrum München, Technical University of Munich and the University of Edinburgh has used an integrated structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation.

4 Jul 2018

New computational method improves ability to track spread of cancer cells

Princeton researchers have developed a new computational method that increases the ability to track the spread of cancer cells from one part of the body to another.

30 Jun 2018

Modified natural killer cells may be new player in CAR-T immunotherapies

Emerging CAR-T immunotherapies leverage modified versions of patient's T-cells to target and kill cancer cells.

29 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Dynamic model helps make predictions about gut microbiome

The human gut is teeming with microbes, each interacting with one another in a mind-boggling network of positive and negative exchanges. Some produce substances that serve as food for other microbes, while others produce toxins -; antibiotics -; that kill their neighbors.

22 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

Doling out pain pills post-surgery: An ingrown toenail not the same as a bypass

What's the right painkiller prescription to send home with a patient after gallbladder surgery or a cesarean section?

22 Jun 2018

WVU researchers increase colorectal cancer screening rates in West Virginia

In West Virginia, where colorectal cancer is the second-deadliest type of cancer, half of all colorectal cancers elude diagnosis until they have already grown beyond the colon. With Medicaid expansion, more West Virginians now have health insurance for cancer screening, yet many barriers to screening persist.

21 Jun 2018