Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Turbine, a simulation-based drug discovery company today announced the closing of an institutional financing round led by Delin Ventures.

From Turbine Simulated Cell Technologies Ltd. 14 Nov 2019

New biomarker discovered in cancer stem cells

In the world of cancer biology, not all biomarkers are created equal. These molecules that alert doctors that an abnormal process may be underway can appear as an array of aberrant proteins, such as hormones, enzymes or signaling molecules, and vary from patient to patient. Because they are a mixed bag, no one drug exists to attack them.

13 Nov 2019

Horizon Discovery announces divestment of animal models business to Envigo

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announces an agreement to divest the Group’s animal research models business unit to Envigo RMS LLC.

From Revvity 11 Nov 2019

Thermo Scientific Aquilos 2 Cryo-FIB reduces sample preparation time

Thermo Fisher Scientific today announced the Thermo Scientific Aquilos 2 Cryo-FIB, a DualBeam system dedicated to the preparation of thin, electron-transparent samples from biological specimens.

From Thermo Fisher Scientific – Electron Microscopy Solutions 11 Nov 2019

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.

10 Nov 2019

Sphere Fluidics and Peak Analysis and Automation introduce integrated micro-plate handling and single cell analysis capabilities

Sphere Fluidics and Peak Analysis and Automation, announce optimization of the Single Cell Analysis System through integration with automated plate handler.

From Sphere Fluidics 7 Nov 2019

MD Anderson, Artios Pharma and ShangPharma collaborate for ATR inhibitor program

The University of Texas MD Anderson Cancer Center, Artios Pharma Limited and ShangPharma Innovation today announce the in-licensing by Artios of a small-molecule ATR inhibitor program, developed jointly by MD Anderson and ShangPharma.

6 Nov 2019

AnaBios receives IDIQ contract to assess drug safety related to cardiac function

The U.S. Food and Drug Administration (FDA) has awarded AnaBios an exclusive Indefinite Delivery Indefinite Quantity (IDIQ) contract to employ adult human primary tissues and cardiomyocytes from organ donors to assess drug safety related to cardiac function.

6 Nov 2019

New stem cell transplant lowers complications for patients with acute blood cancers

The discovery of the UM171 molecule, by Dr. Guy Sauvageau and Anne Marinier, made headlines in 2014 following an article in Science. Hailed by some as a revolution, even a miracle, in the field of blood stem cell transplantation, the UM171 molecule is delivering on its promise.

5 Nov 2019

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

The use of nanoparticles to deliver a drug into specific nerve cells has resulted in significantly improved pain relief.

5 Nov 2019

Nanoparticle drug delivery enhances and prolongs pain relief in animal models

An international team of researchers has used nanoparticles to deliver a drug- one that previously failed in clinical trials for pain- into specific compartments of nerve cells, dramatically increasing its ability to treat pain in mice and rats.

4 Nov 2019

How venom from marine cone snails can be used in pain therapy

Conotoxins are bioactive peptides found in the venom that marine cone snails produce for prey capture and defense.

4 Nov 2019

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the 'runaway train' that is Parkinson's disease.

31 Oct 2019

Olympus SLIDEVIEW™ VS200 Solution with Reliable, Flexible, and High-Throughput Slide Scanning

Using Olympus’ leading-edge X Line™ objectives enables higher resolution, flatter images for outstanding digital slides for quantitative data analysis.

From Evident Corporation - Life Sciences 31 Oct 2019

New contrast agent improves MRI diagnosis of early liver fibrosis

A new compound has been invented to bind to liver cells that are in the early stages of damage, thus making it easier to pick them up using MRI (magnetic resonance imaging).

30 Oct 2019

MRI contrast agent enables early detection of liver disease

Researchers have developed a new MRI contrast dye that enables more accurate and safer detection of early-stage liver disease than currently approved agents.

30 Oct 2019

First effective noninvasive method for diagnosing early-stage liver diseases

A safer and more sensitive contrast dye for MRI tests developed by a team led by Georgia State University researchers may provide the first effective, noninvasive method for detecting and diagnosing early-stage liver diseases, including liver fibrosis.

29 Oct 2019

Drug Discovery News and Research

Further Reading

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

New biomarker discovered in cancer stem cells

Horizon Discovery announces divestment of animal models business to Envigo

Thermo Scientific Aquilos 2 Cryo-FIB reduces sample preparation time

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Sphere Fluidics and Peak Analysis and Automation introduce integrated micro-plate handling and single cell analysis capabilities

MD Anderson, Artios Pharma and ShangPharma collaborate for ATR inhibitor program

AnaBios receives IDIQ contract to assess drug safety related to cardiac function

New stem cell transplant lowers complications for patients with acute blood cancers

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

Nanoparticle drug delivery enhances and prolongs pain relief in animal models

How venom from marine cone snails can be used in pain therapy

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Olympus SLIDEVIEW™ VS200 Solution with Reliable, Flexible, and High-Throughput Slide Scanning

New contrast agent improves MRI diagnosis of early liver fibrosis

MRI contrast agent enables early detection of liver disease

First effective noninvasive method for diagnosing early-stage liver diseases

Newly discovered protein is key to recycling aging mitochondria

PREDiCT: 4th Annual 3D Tissue Models discovery & development

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

eBook: Essential guide to organoids in drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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