Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Canadian scientist discusses about how society could better prepare for future pandemics

Aled Edwards is of two minds about medicine's response to COVID-19. On one hand, he notes, we had life-saving vaccines and therapies less than a year after the discovery of SARS-CoV-2. On the other, more than six million, and possibly as many as 18 million people have died, and global access to advances that can prevent and treat severe disease remains highly inequitable.

11 Mar 2022

High prevalence of new-onset diabetes with ketoacidosis observed in children during COVID-19 pandemic

Research revealed the incidence of type 1 diabetes mellitus with severe diabetic ketoacidosis has increased among genetically susceptible children during the COVID-19 pandemic.

9 Mar 2022

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Researchers assessed the diabetogenic potential of SARS-CoV-2 in a single cell in vitro analysis on the pancreatic islet cells.

9 Mar 2022

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Leptomeningeal disease is a rare complication of several different types of cancer, including melanoma. It occurs when tumor cells migrate to the cerebrospinal fluid and the tissue that surrounds the brain and spinal column known as the meninges.

8 Mar 2022

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

Glucocorticoid steroids improved muscle performance through distinct, sex-specific molecular mechanisms in mice, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

7 Mar 2022

Clinical decision support system may help improve cardiovascular health in patients with severe mental illness

In a new study, researchers demonstrated that they can significantly lower cardiovascular risk for patients with severe mental illness (SMI) by using a clinical decision support system that prompts doctors to provide individualized informational handouts about a patient's cardiovascular risk and treatment recommendations.

7 Mar 2022

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Many people aspire to live longer, healthier lives. A researcher at Baylor College of Medicine, Dr. Rajagopal Sekhar, associate professor of medicine in the section of endocrinology, diabetes and metabolism, has been studying aging for the past 20 years to better understand its biological underpinnings and develop nutritional strategies to promote healthy aging.

7 Mar 2022

Diabetes and the mTOR pathway in COVID-19 patients

A new study discusses the possible etiopathogenetic mechanisms associated with diabetes that could enhance the severity of COVID-19.

6 Mar 2022

$35 insulin cap is welcome, popular, and bipartisan. But Congress may not pass it anyway.

Democrats in the Senate are primed this month to make their first attempt at salvaging one of the most popular elements of President Joe Biden’s stalled Build Back Better plan — the proposal to cap insulin costs at $35 a month.

4 Mar 2022

New inhibitor shows promise in fighting obesity and preventing heart disease

An interdisciplinary research team at The University of Texas at San Antonio has successfully developed an innovative inhibitor that shows promise in fighting obesity and potentially preventing heart disease.

4 Mar 2022

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

Helsingin yliopisto (University of Helsinki) Insulin is a vital hormone produced by pancreatic beta cells. Type 1 diabetes is caused by the destruction of these cells, which results in patients having to replace the lost insulin with multiple daily injections.

4 Mar 2022

California governor’s big promises on drug prices are slow to materialize

When Gov. Gavin Newsom took office in 2019, he promised to lower prescription drug costs for all Californians.

4 Mar 2022

Study identifies new ways to enhance SC-beta cell survivability through genetic manipulation

Recent advances in the transplantation of stem cell-derived insulin-producing beta cells (SC-beta cells) to treat type 1 diabetes (T1D) has generated considerable interest and excitement.

3 Mar 2022

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications.

3 Mar 2022

Study illustrates the link between e-cigarette use and increased odds of prediabetes

An analysis of data from a large, nationally representative survey of the US population shows that e-cigarette use is associated with increased odds of prediabetes.

3 Mar 2022

Fact check: Biden sets high bar in 1st State of the Union speech

President Joe Biden argued forcefully for the power of democracy while calling out Russia's invasion of Ukraine in a March 1 State of the Union address that soon turned to the domestic concerns of the economy, inflation, and covid-19.

2 Mar 2022

Researchers launch a multi-center trial to investigate new treatment for pediatric type 1 diabetes

Researchers at Massachusetts General Hospital, in partnership with NYU Langone Health, have launched a multi-center clinical trial to investigate a new treatment for pediatric type 1 diabetes even in subjects with established disease.

1 Mar 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

Research shows intergenerational effects of preconception opioids in male offspring rats

New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy-; even if not used during pregnancy itself-; could result in a higher likelihood that a mother's male offspring will develop type 2 diabetes and metabolic syndrome, conditions that increase the risk of heart disease and stroke.

28 Feb 2022

Exercise may help reduce the risk of blood clots in patients with aggressive form of NAFLD

Exercise may help certain patients with nonalcoholic fatty liver disease (NAFLD) reduce their risk of developing blood clots, according to a new study by Penn State College of Medicine researchers.

28 Feb 2022

Insulin News and Research

Further Reading

Canadian scientist discusses about how society could better prepare for future pandemics

High prevalence of new-onset diabetes with ketoacidosis observed in children during COVID-19 pandemic

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

Clinical decision support system may help improve cardiovascular health in patients with severe mental illness

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Diabetes and the mTOR pathway in COVID-19 patients

$35 insulin cap is welcome, popular, and bipartisan. But Congress may not pass it anyway.

New inhibitor shows promise in fighting obesity and preventing heart disease

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

California governor’s big promises on drug prices are slow to materialize

Study identifies new ways to enhance SC-beta cell survivability through genetic manipulation

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Study illustrates the link between e-cigarette use and increased odds of prediabetes

Fact check: Biden sets high bar in 1st State of the Union speech

Researchers launch a multi-center trial to investigate new treatment for pediatric type 1 diabetes

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

Research shows intergenerational effects of preconception opioids in male offspring rats

Exercise may help reduce the risk of blood clots in patients with aggressive form of NAFLD

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