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New online tool can help patients to better understand their GI issues

Although GI disorders are among the most common medical conditions, many patients don't consider their symptoms serious enough to consult a physician and are left suffering in silence.

13 Apr 2017

DNA methods can help identify microbial hot spots in buildings

Usually associated with humid and sordid slums, mold is a frequent finding in wealthy homes too. Even the fanciest buildings may harbor hot spots where fungi and other microorganisms subtly proliferate, triggering problems that range from unpleasant smells to severe sickness.

13 Apr 2017

Lab-on-a-chip designed to predict woman's risk of preterm birth

In the United States alone, a half million babies are born preterm; worldwide, the number is an estimated 15 million. Complications associated with preterm birth are the no. 1 cause of death for children under 5, and those who live often face a range of health problems.

13 Apr 2017

Intricate prosthetic eyes give recipients a new outlook on life

Two enormous bulletin boards take up much of the wall space in the tiny office and laboratory. Photos of children, some just a few months old, cover each panel.

13 Apr 2017

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Using the new gene-editing enzyme CRISPR-Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the lab.

13 Apr 2017

NIH study provides unprecedented detail on host response to Ebola virus disease

Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.

12 Apr 2017

NIH scientists identify protein complexes involved in promoting HSV infection and reactivation

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle has frustrated scientists for years.

12 Apr 2017

Study shows new prospects for understanding mechanisms underlying vision

New approaches to the study of vision both from the neurobiological perspective and with a view to the technological development of artificial vision systems: that is the key result of the research project conducted by SISSA in Trieste in collaboration with the Istituto Italiano di Tecnologia in Rovereto and published in the science journal eLife.

12 Apr 2017

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation.

12 Apr 2017

Transmembrane protein complexes shed light on antibiotic resistance in bacteria

An international team including researchers from MIPT’s Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of the way bacteria process external signals.

12 Apr 2017

Scientists discover novel therapeutic target for retinal neovascularization

A team led by Massachusetts Eye and Ear researchers has identified a novel therapeutic target for retinal neovascularization, or abnormal blood vessel growth in the retina, a hallmark of advanced diabetic eye disease (proliferative diabetic retinopathy).

11 Apr 2017

New nanowire technology may serve as platform to screen drugs for neurological diseases

A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail.

11 Apr 2017

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Marc Symons, PhD, professor in The Feinstein Institute for Medical Research's Karches Center for Oncology Research, is examining if a common medication administered to treat pinworms, could replace the current treatment used for certain brain cancers.

11 Apr 2017

Pupil dilation patterns of speakers and listeners synchronize during shared attention, study finds

A new Dartmouth study finds that listeners are most likely to tune in when a speaker delivers the most emotional peaks of his/her narrative, as revealed by synchronous pupil dilation patterns of speakers and listeners due to shared attention.

11 Apr 2017

Researchers identify 26 novel genes linked to intellectual disability

Researchers at the Centre for Addiction and Mental Health and Queen's University have identified 26 new genes linked to intellectual disability. Currently most patients with intellectual disability receive no molecular diagnosis, which significantly affects their health and shortens their lifespan.

11 Apr 2017

JAX professor receives grant from National Eye Institute to study diseases of retinal pigment epithelium

The National Eye Institute has awarded Jackson Laboratory Professor Patsy Nishina, Ph.D., and Associate Professor Gregory Carter, Ph.D., a four-year grant totaling $2,414,304 to study diseases of the retinal pigment epithelium (RPE), with the goal of identifying druggable targets for age-related macular degeneration and other heritable retinal diseases.

11 Apr 2017

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science Center at Houston.

11 Apr 2017

Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

The discovery of a protein signature that is highly predictive of leukemia could lead to novel treatments of the leading childhood cancer, according to new study showing that competition among certain proteins causes an imbalance that leads to leukemia.

11 Apr 2017

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Zika virus is a mosquito-borne infectious disease linked to certain birth defects in infants in South and Central America and the United States.

11 Apr 2017

Scientists use time-lapse video to identify cells that trigger blood stem cell development

Like private investigators on a stake out, St. Jude Children's Research Hospital scientists used patience and video surveillance-like tools to identify cells that trigger blood cell development.

10 Apr 2017

Laboratory News and Research

New online tool can help patients to better understand their GI issues

DNA methods can help identify microbial hot spots in buildings

Lab-on-a-chip designed to predict woman's risk of preterm birth

Intricate prosthetic eyes give recipients a new outlook on life

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

NIH study provides unprecedented detail on host response to Ebola virus disease

NIH scientists identify protein complexes involved in promoting HSV infection and reactivation

Study shows new prospects for understanding mechanisms underlying vision

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

Transmembrane protein complexes shed light on antibiotic resistance in bacteria

Scientists discover novel therapeutic target for retinal neovascularization

New nanowire technology may serve as platform to screen drugs for neurological diseases

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Pupil dilation patterns of speakers and listeners synchronize during shared attention, study finds

Researchers identify 26 novel genes linked to intellectual disability

JAX professor receives grant from National Eye Institute to study diseases of retinal pigment epithelium

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Scientists use time-lapse video to identify cells that trigger blood stem cell development

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