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Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

Scientists at The Scripps Research Institute have described the regulatory mechanism of an important human protein called Rac that controls a number of biological processes and is directly implicated in several human diseases.

2 Jul 2004

How DNA repair machinery detects and corrects errors in DNA replication

Biochemists at Duke University Medical Center have discovered key components that enable the cell's DNA repair machinery to adeptly launch its action in either direction along a DNA strand to strip out faulty DNA.

2 Jul 2004

Three-dimensional cryo-electron microscope may help guide the design of new antibiotics

Understanding the last step of protein synthesis – the basic process of translating DNA into its final protein product – just became more clear both literally and figuratively.

1 Jul 2004

Protein research may help develop new antibiotics

New findings about a protein that keeps cells alive by opening and closing pores within a cell's membrane may open the door to the development of new antibiotics.

30 Jun 2004

Relatively difficult for the AIDS virus to develop resistance to the drug, tenofovir, or the DAPY (diarylpyrimidine) family of compounds

HIV is a moving target, unpredictably changing direction to elude anti-AIDS drugs, but researchers at Rutgers are clearly on the track of solutions to combat HIV drug resistance.

29 Jun 2004

RNA enzyme research may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars

Research aimed at teasing apart the workings of RNA enzymes eventually may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars, according to University of Michigan researcher Nils Walter.

29 Jun 2004

Continued commercial development of research into DNA repair

Recent developments have greatly improved the understanding of the mechanisms used by cells to identify and repair breaks in DNA, and the potential for drugs that target DNA repair in the treatment of a range of human diseases including cancer.

28 Jun 2004

Blood hormone may be key to appetite suppression and obesity control

How the body naturally regulates appetite through the presence of a blood hormone may offer the prospect of a safer and more effective method of weight control, according to Dr. Leonard Firestone of Manhattan Pharmaceuticals.

28 Jun 2004

A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive

Physicians may be able to make early decisions on the best treatment for breast cancer, thanks to research published in Breast Cancer Research today.

28 Jun 2004

Treating cocaine addiction with a virus

Scientists at The Scripps Research Institute have designed a potentially valuable tool for treating cocaine addiction by creating a modified "phage" virus that soaks up the drug inside the brain.

24 Jun 2004

Genetic variation that doubles the risk for rheumatoid arthritis

A team of researchers has discovered a genetic variation that doubles the risk for rheumatoid arthritis (RA).

24 Jun 2004

Genetically engineering viruses to carry a suicide gene into ovarian cancer cells

Genetically engineering viruses to carry a suicide gene into ovarian cancer cells could become a potent way to tackle the disease, a leading Cancer Research UK scientist reveals at a conference in Glasgow today (Tuesday).

22 Jun 2004

Paclitaxel analog kills more cancer cells than natural product

Paclitaxel, a natural compound from yew trees, is the world's best-selling anticancer drug. Several analogs are in clinical trial, with others in preclinical development. One problem that paclitaxel and all its analogs share, however, is that they are all highly complex compounds, and cannot be prepared synthetically in a commercially viable way.

21 Jun 2004

New gene found in genetic wasteland

In a region of DNA long considered a genetic wasteland, Harvard Medical School researchers have discovered a new class of gene.

20 Jun 2004

A natural molecule that blocks a key bacterial enzymes could lead to a new generation of antibiotics

Rutgers scientists have deciphered the complex mechanics of microcin J25 (MccJ25), a tiny, natural molecule that acts like a cork in a bottle to block a key bacterial enzyme – potentially leading to a new generation of antibiotics.

17 Jun 2004

3dgenome program should lead to a breakthrough in our understanding of how our genome functions

Under the EU Sixth Framework Programme (FP6) for Research and Development (2002-2006) 2.2 million Euros have been awarded to the 3DGENOME-research program.

17 Jun 2004

Potential new strategy for blocking tumor growth

Targeting a master molecule that helps cancer cells survive when blood oxygen levels are low may offer a potentially powerful strategy for blocking tumor growth, say researchers at The University of Texas M. D. Anderson Cancer Center.

16 Jun 2004

New target to stop breast cancer growth

Two proteins that normally help cells move from place to place and are made in large quantities in breast cancer cells work together to promote the survival and spread of breast cancer, according to a new study by scientists at The University of Texas M. D. Anderson Cancer Center.

15 Jun 2004

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population. In a new study, scientists may have found a culprit: a serious deficiency of nitric oxide, a small molecule vital in the regulation of blood flow and blood pressure.

11 Jun 2004

Project aimed at eliminating anthrax as a potential weapon for terrorists

La Trobe University scientists are using their own unique peptide 'library' containing a thousand million molecular sequences in a project aimed at eliminating anthrax as a potential weapon for terrorists.

10 Jun 2004

Molecule News and Research

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

How DNA repair machinery detects and corrects errors in DNA replication

Three-dimensional cryo-electron microscope may help guide the design of new antibiotics

Protein research may help develop new antibiotics

Relatively difficult for the AIDS virus to develop resistance to the drug, tenofovir, or the DAPY (diarylpyrimidine) family of compounds

RNA enzyme research may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars

Continued commercial development of research into DNA repair

Blood hormone may be key to appetite suppression and obesity control

A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive

Treating cocaine addiction with a virus

Genetic variation that doubles the risk for rheumatoid arthritis

Genetically engineering viruses to carry a suicide gene into ovarian cancer cells

Paclitaxel analog kills more cancer cells than natural product

New gene found in genetic wasteland

A natural molecule that blocks a key bacterial enzymes could lead to a new generation of antibiotics

3dgenome program should lead to a breakthrough in our understanding of how our genome functions

Potential new strategy for blocking tumor growth

New target to stop breast cancer growth

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

Project aimed at eliminating anthrax as a potential weapon for terrorists

A new way of characterising biomolecules eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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