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Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Building on earlier work in designing chimeric human-simian immunodeficiency viruses (SHIVs) that serve as a model of HIV infection of humans, George M. Shaw, MD, PhD, a professor of Hematology/Oncology and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has received $16.3 million over five years from the National Institute of Allergy and Infectious Diseases to develop a long-sought-after HIV vaccine.

22 Mar 2017

Endocrine Society releases new guideline to help diagnose and treat hypothalamic amenorrhea

Female athletes and women who have eating disorders are prone to developing a condition called hypothalamic amenorrhea that causes them to stop menstruating. The Endocrine Society today issued a Clinical Practice Guideline advising healthcare providers on ways to diagnose and treat this condition.

22 Mar 2017

Machine learning helps researchers uncover cellular control networks

The flow of information between cells in our bodies is exceedingly complex: sensing, signaling, and influencing each other in a constant flow of microscopic engagements. These interactions are critical for life, and when they go awry can lead to the illness and injury.

22 Mar 2017

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

A Phase I clinical trial that targeted individuals with new onset paraplegia to evaluate the safety of transplanting their own potentially neuroprotective Schwann cells into a trauma-induced spinal cord lesion showed no evidence of adverse effects after 1 year.

22 Mar 2017

Researchers find new way to expand, preserve cord-blood cells as potential treatment for Type 1 diabetes

For parents, storing their newborn baby's umbilical cord blood is a way to preserve potentially lifesaving cells. Now, a group of University of Florida Health researchers has found a way to expand and preserve certain cord-blood cells as a potential treatment for Type 1 diabetes.

22 Mar 2017

Researchers develop new software tool to provide fast, accurate quantification of gene expression

A group of computational biological researchers, led by Stony Brook University's Rob Patro, an Assistant Professor in the Department of Computer Science in the College of Engineering and Applied Sciences, has developed a new software tool, Salmon — a lightweight method to provide fast and bias-aware quantification from RNA-sequencing reads.

22 Mar 2017

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Consumption of the synthetic drug MDPV -a powerful psychostimulant known as 'cannibal drug'- in adolescence, can increase vulnerability of cocaine addiction during adulthood, according to a study carried out with laboratory animals and led by the researchers Elena Escubedo, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the UB and Olga Valverde, head of the Neurobiology of Behaviour Research Group of Pompeu Fabra University.

22 Mar 2017

Advances in SiPM for Medical Imaging

The silicon photomultiplier, or SiPM, is a solid state detector representing the next generation of photon counting detector that can be used in medical imaging.

From Hamamatsu Photonics Europe 22 Mar 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

FARE announces recipients of 2017 Investigator in Food Allergy Awards

Food Allergy Research & Education, the world's largest private source of funding for food allergy research, is pleased to announce the recipients of the 2017 FARE Investigator in Food Allergy Awards after an extraordinarily competitive review process, with more than two dozen researchers submitting high-quality proposals.

22 Mar 2017

Brain inspiration leads to faster, more efficient cybersecurity system

Cybersecurity is critical -- for national security, corporations and private individuals. Sophisticated cybersecurity systems excel at finding "bad apples" in computer networks, but they lack the computing power to identify the threats directly.

22 Mar 2017

Study identifies potential Achilles heel of kinase-driven cancers

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models.

22 Mar 2017

Parasitic fish offers unique insights into evolution of gut neurons in ancient vertebrates

Lamprey are slimy, parasitic eel-like fish, one of only two existing species of vertebrates that have no jaw. While many would be repulsed by these creatures, lamprey are exciting to biologists because they are so primitive, retaining many characteristics similar to their ancient ancestors and thus offering answers to some of life's biggest evolutionary questions

21 Mar 2017

Treatment with interferon may ease symptoms of Ebola patients

A pilot study of a class of drugs used to treat hepatitis and some forms of multiple sclerosis has been shown for the first time to ease symptoms of Ebola patients, while also increasing their survival.

21 Mar 2017

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Chemists from Russia and Switzerland created biosafe luminescent nanoparticles for imaging tumors and blood vessels damaged by heart attack or stroke.

21 Mar 2017

Penn scientists discover method that appears to provide early warning of transplant rejection

Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient's immune system attacks, or "rejects," the donated organ.

21 Mar 2017

Research findings hold promise to generate blood cell precursors from hPSCs

The Galat laboratory at Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, has developed an elegant system to derive blood cell precursors from human pluripotent stem cells (hPSC).

21 Mar 2017

Mettler Toledo’s Laboratory Expertise Library provides information on efficient sample preparation

In a typical analytical workflow, 49% of out-of-specification (OOS) errors can be attributed to either sample processing steps or operator error. In addition, the sample processing steps account for 61% of the manual workload.

From Mettler-Toledo International Inc. 21 Mar 2017

Sandia researchers develop smartphone-based device to rapidly detect mosquito-borne viruses

Add rapid, mobile testing for Zika and other viruses to the list of things that smartphone technology is making possible. Researchers at Sandia National Laboratories have developed a smartphone-controlled, battery-operated diagnostic device that weighs under a pound, costs as little as $100 and can detect Zika, dengue and chikungunya within 30 minutes.

21 Mar 2017

AXT introduces super-resolution fluorescence microscope capable of single molecule imaging in Australia and NZ

AXT are proud to announce that they have recently been appointed the exclusive Australian and New Zealand distributor for Oxford Nanoimaging (ONI). ONI is a UK-based company that has commercialised the “Nanoimager” a revolutionary super-resolution fluorescence microscope capable of single molecule imaging.

From AXT Pty Ltd 21 Mar 2017

Laboratory News and Research

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Endocrine Society releases new guideline to help diagnose and treat hypothalamic amenorrhea

Machine learning helps researchers uncover cellular control networks

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

Researchers find new way to expand, preserve cord-blood cells as potential treatment for Type 1 diabetes

Researchers develop new software tool to provide fast, accurate quantification of gene expression

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Advances in SiPM for Medical Imaging

Changes in the vascular system could play role in initiating Alzheimer’s disease

FARE announces recipients of 2017 Investigator in Food Allergy Awards

Brain inspiration leads to faster, more efficient cybersecurity system

Study identifies potential Achilles heel of kinase-driven cancers

Parasitic fish offers unique insights into evolution of gut neurons in ancient vertebrates

Treatment with interferon may ease symptoms of Ebola patients

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Penn scientists discover method that appears to provide early warning of transplant rejection

Research findings hold promise to generate blood cell precursors from hPSCs

Mettler Toledo’s Laboratory Expertise Library provides information on efficient sample preparation

Sandia researchers develop smartphone-based device to rapidly detect mosquito-borne viruses

AXT introduces super-resolution fluorescence microscope capable of single molecule imaging in Australia and NZ

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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