Interferon News and Research

RSS

New approach may help kill Mycobacterium tuberculosis

Current treatment regimens for Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, are long, complex, and hard for people to sustain. Moreover, the bacteria often develop drug resistance, and many people harbor multi-drug-resistant strains. In 2018 alone, nearly 1.5 million people died from tuberculosis worldwide.

12 Nov 2019

Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Zika virus infection in the womb produces altered immune responses and sex-specific brain abnormalities in apparently healthy pig offspring, according to a study published November 14 in the open-access journal PLOS Pathogens by Uladzimir Karniychuk of the University of Saskatchewan, and colleagues.

From PLOS ONE 11 Nov 2019

Scientists discover cell protein crucial in preventing viral replication

A research team has discovered a protein without which cells infected by viruses cannot trigger an immune response, leading to 100% mortality with even non-disease-producing strains. The discovery of the new Z-DNA binding protein, or ZBP1, was reported in the journal Frontiers in Microbiology. It could help develop new treatment methods for viruses that target the nervous system such as the Zika or West Nile Encephalitis virus.

6 Nov 2019

Moffitt study discovers cellular mechanism controlling tumor cell recognition by immune cells

Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma.

1 Nov 2019

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Sometimes vaccines need a little help to protect people against infectious diseases.

31 Oct 2019

Factor responsible for formation of white blood cells has regulatory effect on adaptive immunity

Granulocyte colony-stimulating factor, which causes division and differentiation of bone marrow cells depending on the body's need for leukocytes, has a significant regulatory effect not only on innate, but also on adaptive immunity.

31 Oct 2019

DNA sequences encode information in many different ways

DNA sequences encode information in many different ways. Codons specify the amino acids involved in making a protein.

30 Oct 2019

New cellular immunotherapy for cancers

A new study published in the journal Nature Communications on 22 October 2019 reports a new approach to cancer treatment that increases the immune capability of T lymphocytes against malignant cancers. This allows the T cells to successfully infiltrate and destroy these tumors. Animal trials have been completed and the researchers are planning clinical trials in human beings next.

26 Oct 2019

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists at the HudsonAlpha Institute for Biotechnology have pinpointed epigenetic differences in the way lupus affects black women compared to other lupus patients, revealing important mechanics of the puzzling disease.

24 Oct 2019

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body's healthy tissues and organs.

23 Oct 2019

Adding plant-based compound to gene therapy could improve treatment outcomes

Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia.

17 Oct 2019

Dysfunctions in blood vessels contribute to the development of chronic inflammatory bowel diseases

In Germany alone there are around 400,000 patients who suffer from chronic inflammatory bowel diseases. For the first time, researchers at Universitätsklinikum Erlangen have discovered that dysfunctions in blood vessels play a significant role in the development of such diseases.

9 Oct 2019

New discovery brings scientists closer to developing an RSV vaccine

Scientists have made an important discovery that could lead to a vaccine that will protect against respiratory syncytial virus (RSV).

9 Oct 2019

Vaccine for deadly RSV could be on the way, scientists say

A vaccine for the common and sometimes deadly RSV (respiratory syncytial virus) has been elusive, but scientists say a new discovery puts them much closer to success.

9 Oct 2019

Arthritis drug could be used to treat lichen planus skin rash

Constant itchy, painful bumps, scaly arms and legs, and damaged nails make lichen planus an inflammatory skin disease that's both frustrating and painful for patients trying to keep their quality of life.

26 Sep 2019

Acne may be a natural, transient inflammatory state when facial skin is exposed to microbes

Adolescent acne does not always result in a pathological condition; rather, it may be a natural, transient inflammatory state occurring when the maturing facial skin is exposed to new microbes and enhanced production of an oily substance called sebum, according to a Forum article published on September 26 in the journal Trends in Immunology.

25 Sep 2019

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

A team from Roswell Park Comprehensive Cancer Center is moving a new three-part strategy for treating advanced cancers forward with support from a U.S. Department of Defense grant to Pawel Kalinski, MD, PhD, Vice Chair for Translational Research and Rustum Family Professor for Molecular Therapeutics and Translational Research at the Buffalo, N.Y.-based cancer center.

18 Sep 2019

Interferon News and Research

New approach may help kill Mycobacterium tuberculosis

Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Scientists discover cell protein crucial in preventing viral replication

Moffitt study discovers cellular mechanism controlling tumor cell recognition by immune cells

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Factor responsible for formation of white blood cells has regulatory effect on adaptive immunity

DNA sequences encode information in many different ways

New cellular immunotherapy for cancers

Scientists pinpoint epigenetic differences in the way lupus affects black women

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

Adding plant-based compound to gene therapy could improve treatment outcomes

Dysfunctions in blood vessels contribute to the development of chronic inflammatory bowel diseases

New discovery brings scientists closer to developing an RSV vaccine

Vaccine for deadly RSV could be on the way, scientists say

Arthritis drug could be used to treat lichen planus skin rash

Acne may be a natural, transient inflammatory state when facial skin is exposed to microbes

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

Mutant live attenuated Ebola virus elicits protective immunity in monkeys

A detailed map to understand how viruses infect human cells

Researchers find a weak spot in cancer cells

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest News