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Injections of adult stem cells could repair hearts

Injections of adult stem cells into damaged heart tissue significantly improved heart function in patients with severe congestive heart failure, according to results of the first prospective randomized trial of the experimental therapy presented today at the American Association for Thoracic Surgery.

26 Apr 2004

Avoid feeding infants fluoridated water, researchers caution

Infant formulas prepared with fluoridated water increase dental fluorosis risk, according to the April 2004 Journal of the American College of Nutrition(1) and other studies. To prevent this tooth staining, researchers caution against mixing infant formulas with fluoridated water.

23 Apr 2004

HHS Launches Organ Donation Education Program for High School Students

HHS Secretary Tommy G. Thompson today released a new organ and tissue donation education program to raise awareness among high school students and to help them make informed decisions about donation.

20 Apr 2004

Gene discovery could improve anemia treatment in patients

Patients with inflammatory diseases such as arthritis, chronic infections and some types of cancer, often become anemic – a condition called anemia of chronic disease (ACD). While ACD rarely kills patients, it can make their lives miserable.

18 Apr 2004

Stem cell personal space determines their future

Johns Hopkins scientists report that restricting the shape and personal space of human stem cells from bone marrow is more important than any known molecular signal in determining the cell type they become.

16 Apr 2004

Three hours exercise reduces risk of breast cancer

Three hours of moderate exercise per week significantly reduced circulating estrogens in postmenopausal women, according to a new study published in the current issue of Cancer Research. The finding may explain why women who exercise regularly lower their risk for breast cancer.

16 Apr 2004

Muscle stem cells morph to resemble nerve cells

Taking a major step forward in stem cell biology, researchers at The University of Texas M. D. Anderson Cancer Center have turned muscle progenitor cells — stem cells that are “committed” to becoming muscle tissue — into cells that look and act like neurons (nerve cells).

14 Apr 2004

Drug duo prevents life-threatening condition in children undergoing stem cell transplant

A drug duo appears to be a safe and effective way to prevent a serious condition called graft-versus-host-disease (GVHD) in youngsters undergoing a stem cell transplant

14 Apr 2004

Growth hormones combat Crohn’s disease, cardiac disorders and improve fertility in invitro fertilisation

New treatments for breast cancer, skin and wound healing and obesity will be revealed at an international conference in Cairns, Australia next week.

13 Apr 2004

Estrogen-alone hormone therapy had no effect on coronary heart disease risk

A large, multi-center heart disease prevention study, part of the Women's Health Initiative (WHI), found that estrogen-alone hormone therapy had no effect on coronary heart disease risk but increased the risk of stroke for postmenopausal women.

13 Apr 2004

Kentucky's first robotic procedure treats prostate

Earlier this year, the University of Kentucky Hospital was the first hospital in Kentucky to perform a minimally invasive, coronary artery bypass graft using surgical robotic instruments.

12 Apr 2004

Britain's NHS to buy large volume of mobile MRI scanners

British Health Secretary John Reid today invited bidders to supply the NHS with new, mobile, 'state of the art' MRI scanners and highly qualified staff to help cut waiting times across England. These new scanners will targeted at areas of greatest need. It's expected that they will be operational this summer.

8 Apr 2004

Shunning shoulder pain can cause more damage in the long run

Senator John Kerry is one of the millions of Americans suffering from shoulder pain. Depending on the nature of the problem, conservative nonoperative methods of treatment are often recommended before surgery. However, in some instances such as Kerry’s, surgery is necessary in order to prevent more difficulties later. The American Academy of Orthopaedic Surgeons (AAOS) advises those suffering shoulder pain to consult their doctor instead of ignoring the pain. Early, correct diagnosis and treatment of shoulder problems can make a significant difference in the long run.

7 Apr 2004

Cinacalet helps control overactive thyroids, a major complication of advanced kidney disease

A new drug can help control an overactive thyroid, a major complication of advanced kidney disease, by playing a trick on the gland, a new study finds. The drug, cinacalet, is much more effective at keeping the parathyroid gland working normally than a placebo, according to the study. It may be a good alternative to standard therapy, researchers said.

7 Apr 2004

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Continuing studies about an important regulatory protein kinase complex called I-kappa-B kinase (or IKK) have now shown that a subunit of IKK – IKK alpha – influences the outer layer of skin in developing mice to control the eventual shape of the full-grown skeleton and skull.

7 Apr 2004

Molecular analyses of leukemia patients suggest strategies for better treatments

The cure rate for pediatric acute lymphoblastic leukemia (ALL) might continue to rise with improved use of conventional therapies. But even more effective and less toxic therapies based on genetic and pharmacogenetic studies might one day push the success rate close to 100 percent, according to an article published by investigators at St. Jude Children’s Research Hospital in the April 8 issue of the New England Journal of Medicine.

7 Apr 2004

Time-reversal acoustics research promises medical breakthroughs

Scientists have not yet found a way to actually make time run backward, but in the cutting-edge world of recent acoustics research, they have shown a way to make sound waves run backward in a kind of ultra-focused reverse echo. By the technology known as time-reversal acoustics, sound waves - in exact reverse order from the original sound - echo directly and very precisely back to their source point.

7 Apr 2004

FDA accepts REMICADE® (infliximab) for the treatment of early rheumatoid arthritis

Centocor, Inc., announced today that the U.S. Food and Drug Administration (FDA) has accepted its filing of a supplemental Biologics License Application (sBLA) for REMICADE® (infliximab) as first-line therapy, in combination with methotrexate, for the treatment of early rheumatoid arthritis (RA) patients with moderately-to-severely active disease. REMICADE®, in combination with methotrexate, is currently indicated in the U.S. for reducing signs and symptoms, inhibiting the progression of structural damage and improving physical function in patients with moderately-to-severely active RA who have had an inadequate response to methotrexate alone.

6 Apr 2004

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Researchers at Northwestern University have devised a method to induce embryonic stem cells to develop into bone marrow and blood cells. Injecting the stem cells into the bone marrow cavity of mice whose bone marrow cells had been depleted restored production of blood cells, including cells of the immune system, which normally are created in the bone marrow.

6 Apr 2004

Phase 3 study of drug teduglutide in patients with short bowel syndrome

Teduglutide is an analog of glucagon-like peptide 2 (GLP-2), a naturally occurring hormone that regulates the growth, proliferation and maintenance of cells lining the gastrointestinal tract. Teduglutide has been shown in animal studies and previous human clinical trials to increase the size and number of these cells, thereby increasing the absorptive surface area of the intestines.

6 Apr 2004

Bone News and Research

Injections of adult stem cells could repair hearts

Avoid feeding infants fluoridated water, researchers caution

HHS Launches Organ Donation Education Program for High School Students

Gene discovery could improve anemia treatment in patients

Stem cell personal space determines their future

Three hours exercise reduces risk of breast cancer

Muscle stem cells morph to resemble nerve cells

Drug duo prevents life-threatening condition in children undergoing stem cell transplant

Growth hormones combat Crohn’s disease, cardiac disorders and improve fertility in invitro fertilisation

Estrogen-alone hormone therapy had no effect on coronary heart disease risk

Kentucky's first robotic procedure treats prostate

Britain's NHS to buy large volume of mobile MRI scanners

Shunning shoulder pain can cause more damage in the long run

Cinacalet helps control overactive thyroids, a major complication of advanced kidney disease

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Molecular analyses of leukemia patients suggest strategies for better treatments

Time-reversal acoustics research promises medical breakthroughs

FDA accepts REMICADE® (infliximab) for the treatment of early rheumatoid arthritis

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Phase 3 study of drug teduglutide in patients with short bowel syndrome

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