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New treatment significantly improves long-term outlook for breast cancer survivors

An updated analysis from an international clinical trial of the drug letrozole was presented on June 8, 2004 at the American Society of Clinical Oncology annual meeting in New Orleans.

11 Jun 2004

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

A study by researchers at Cornell University suggests that higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes.

10 Jun 2004

Non-aspirin pain drugs may help men with recurrent prostate cancer

Early results from a University of North Carolina at Chapel Hill School of Medicine study may determine if drugs called Cox-2 inhibitors, a newer type of non-aspirin pain medicine now widely prescribed for arthritis symptoms, may benefit men with recurrent prostate cancer.

10 Jun 2004

Russian doctors appreciate benefits of natural remedies

"It would appear that American doctors have a long way to go compared to Russian doctors who are, after recognizing the limited results with traditional drugs, are now successfully testing natural remedies," according to nutritional researcher Peter Gillham.

10 Jun 2004

Patent issued for GHB, date rape drug test

A patent for a highly sensitive test to detect the presence of the "date rape" drug, GHB, has recently been granted to the University of California, Santa Barbara.

9 Jun 2004

SU11248 proves effective in the treatment of gastrointestinal stromal tumors

A drug originally developed to block the formation of blood vessels in tumors has been shown to overcome resistance to treatment with Gleevec in patients with gastrointestinal stromal tumors (GIST).

9 Jun 2004

Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Researchers from the Johns Hopkins Kimmel Cancer Center, Indiana University and the University of Michigan have found that some women have a gene mutation that may decrease the effectiveness of tamoxifen, a commonly used breast cancer drug.

7 Jun 2004

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Research presented today showed that the investigational drug, LAF237, the first in a new class, improved glycemic control in patients with type 2 diabetes. In this study, LAF237, which is administered as a tablet to be taken orally, was added to the standard diabetes treatment metformin in patients whose diabetes was not adequately controlled by metformin alone.

7 Jun 2004

Research may help treat muscular dystrophies and other muscle diseases caused by glycosylation defects

Expressing high levels of a sugar-adding protein known as LARGE in mice that lack the protein can prevent muscular dystrophy in these animals, according to studies by researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.

7 Jun 2004

New way to identify cell growth

In a discovery that has relevance in a variety of fields, including human health, UC Riverside Assistant Professor of Biochemistry Frank Sauer and colleagues at UC Riverside, in Germany, and in Wisconsin, have found a new way to identify when a living cell begins to grow.

5 Jun 2004

New way to identify when a living cell begins to grow

3 Jun 2004

Scientists reveal the crystal structure of the first described enzymatic RNA

Scientists in the department of molecular biophysics and biochemistry at Yale revealed the crystal structure of the first described enzymatic RNA - what it looks like and how it reacts - in the journal Nature.

2 Jun 2004

Understanding focal adhesion kinase (FAK) may lead to new cancer treatments

Scientists at the University of North Carolina at Chapel Hill have found an unexpected way to turn off a cellular enzyme involved in the progression of several types of human cancers.

2 Jun 2004

Genes that allow nerve cells to communicate may have come from bacteria eons ago

Some of the genes that allow nerve cells and some other types of cells to send elaborate chemical messages to each other appear to have been transferred to animals or their immediate ancestors from bacteria eons ago.

2 Jun 2004

New therapy to send cancer-killing drugs directly to tumours

Disguising a molecule to get it past the body's immune system could greatly enhance the success of a groundbreaking new therapy, Cancer Research UK scientists report in the British Journal of Cancer this week.

2 Jun 2004

Cigarette smoke transforms healthy saliva into a deadly cocktail

Cigarette smoke transforms healthy saliva into a deadly cocktail that can accelerate mouth cancer, according to new research in the British Journal of Cancer.

2 Jun 2004

Prescribing ACE inhibitors to in-patients is important, but outpatients need ongoing support

Use of angiotensin-converting enzyme (ACE) inhibitors by heart failure patients drops sharply within a month after they go home from the hospital and then continues to decline, according to a new study in the June 2, 2004 issue of the Journal of the American College of Cardiology.

2 Jun 2004

Marijuana use does not appear to be associated with an increased risk of developing oral cancer

Contrary to previous research findings that have suggested a link, marijuana use does not appear to be associated with an increased risk of developing oral cancer, according to a large, population-based study led by researchers at Fred Hutchinson Cancer Research Center.

1 Jun 2004

Women who regularly take aspirin at lower risk of breast cancer

Women who regularly take aspirin seem to be at lower risk of the most common type of breast cancer than those who do not take aspirin, report researchers from Columbia University's Mailman School of Public Health and College of Physicians & Surgeons, Weill Cornell Medical College , and New York-Presbyterian Hospital.

31 May 2004

American Heart reports on acute ischemic stroke and increased risk of bleeding in the brain

High blood levels of a cell-regulating protein in patients with acute ischemic stroke can identify those with an increased risk of bleeding in the brain, according to a report in today’s rapid access issue of Stroke: Journal of the American Heart Association.

27 May 2004

Enzyme News and Research

New treatment significantly improves long-term outlook for breast cancer survivors

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

Non-aspirin pain drugs may help men with recurrent prostate cancer

Russian doctors appreciate benefits of natural remedies

Patent issued for GHB, date rape drug test

SU11248 proves effective in the treatment of gastrointestinal stromal tumors

Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Research may help treat muscular dystrophies and other muscle diseases caused by glycosylation defects

New way to identify cell growth

New way to identify when a living cell begins to grow

Scientists reveal the crystal structure of the first described enzymatic RNA

Understanding focal adhesion kinase (FAK) may lead to new cancer treatments

Genes that allow nerve cells to communicate may have come from bacteria eons ago

New therapy to send cancer-killing drugs directly to tumours

Cigarette smoke transforms healthy saliva into a deadly cocktail

Prescribing ACE inhibitors to in-patients is important, but outpatients need ongoing support

Marijuana use does not appear to be associated with an increased risk of developing oral cancer

Women who regularly take aspirin at lower risk of breast cancer

American Heart reports on acute ischemic stroke and increased risk of bleeding in the brain

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