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Scientists develop fluorescent probe to identify cancer stem cells

Cells with stem-cell characteristics appear to be especially important in the formation and metastasis of tumors. Scientists have now developed a universal fluorescent probe for these “cancer stem cells”. As reported in the journal Angewandte Chemie, this dye also selectively kills off the cells.

19 Feb 2018

FDA approves first treatment to reduce risk of NSCLC progression

The U.S. Food and Drug Administration today approved Imfinzi (durvalumab) for the treatment of patients with stage III non-small cell lung cancer (NSCLC) whose tumors are not able to be surgically removed (unresectable) and whose cancer has not progressed after treatment with chemotherapy and radiation (chemoradiation).

18 Feb 2018

Postoperative pain control following extensive pelvic exenteration

In the March issue of Diseases of the Colon & Rectum, surgeons from Australia discuss postoperative pain control following one of the most extensive operations performed for pelvic cancer.

13 Feb 2018

Patients with Huntington's have lesser cancer than general population

Patients with Huntington's disease, a fatal genetic illness that causes the breakdown of nerve cells in the brain, have up to 80 percent less cancer than the general population.

12 Feb 2018

Myriad’s myRisk Hereditary Cancer test finds inherited gene mutations in more than 12% of prostate cancer patients

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, announced today that results from a large 1,162 patient study of the Myriad myRisk Hereditary Cancer test will be featured during the poster presentation at the 2018 Genitourinary Cancer Symposium in San Francisco, Calif.

8 Feb 2018

New tool to monitor patterns and trends of cancer burden across Europe

On the occasion of the World Cancer Day, the European Commission's Joint Research Centre launched the European Cancer Information System (ECIS), which makes it possible to explore geographical patterns and temporal trends of cancer incidence, mortality, and survival from data submitted by some 150 European population-based cancer registries.

6 Feb 2018

Researchers use innovative method to screen kinases for cancer drug's effectiveness

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude from cell surfaces like antennae and can activate cancer-related pathways in virtually all types of cancer when signaling molecules bind with them.

5 Feb 2018

RCSI to lead major study for finding new ways to treat colorectal cancer patients

RCSI is leading an international team of scientists on a major research study “COLOSSUS” which aims to provide new and more effective ways to classify and treat patients with colorectal cancer.

2 Feb 2018

New modular platform offers robust biological approach that targets endless number of diseases

The biological complexity of cancer and other diseases demands a more formidable arsenal of therapies than currently available. Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead only very few selected disease-related genes.

1 Feb 2018

Two bacterial species collaborate to drive development of colon cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.

1 Feb 2018

Scientists discover role of two specific HOX genes in colon cancer development

In breakthrough colon cancer research, scientists at Christiana Care Health System's Center for Translational Cancer Research of the Helen F. Graham Cancer Center & Research Institute have discovered that over-expression of HOXA4 and HOXA9 genes in colon cancer stem cells promotes cell replication and contributes to the overpopulation of stem cells that drives colon cancer development.

31 Jan 2018

After polyps are detected, patients may no longer qualify for free colonoscopies

Insurance coverage of colonoscopies to screen for colorectal cancer is a frequent source of frustration for consumers, including a reader who asks about his situation.

30 Jan 2018

UT Southwestern oncologist highlights need to improve liver cancer screening rates

Patients with cirrhosis should be screened regularly for liver cancer, though few are – in part because busy physicians often don't order the screening tests, said UT Southwestern oncologists.

30 Jan 2018

FDA approves new radioactive drug for treatment of rare digestive tract cancers

The U.S. Food and Drug Administration today approved Lutathera (lutetium Lu 177 dotatate) for the treatment of a type of cancer that affects the pancreas or gastrointestinal tract called gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

29 Jan 2018

Sugar-attaching enzyme found to be abundant in colon cancer cells

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry.

27 Jan 2018

Colonoscopy linked to increased risk of appendicitis

Although the incidence of appendicitis in the United States has been in decline for many years, the condition still affects approximately seven percent of Americans annually.

27 Jan 2018

Research could explain link between high-cholesterol diet and increased colon cancer risk

New UCLA research could help explain the link between a high-cholesterol diet and an elevated risk for colon cancer.

25 Jan 2018

Scientists to test digital nanosensor that lights up cancer tissues

UT Southwestern Simmons Cancer Center scientists next month will begin testing a digital nanosensor that lights up cancer tissue to see whether it can improve the accuracy of cancer surgeries, thereby reducing cancer recurrence and surgical morbidity.