Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Mothers pass on the legacy of stress exposure to future generations

A mother's response to stress can even influence her grandchildren. Biologists at the University of Iowa found that roundworm mothers subjected to heat stress passed, under certain conditions and through modifications to their genes, the legacy of that stress exposure not only to their offspring but even to their offspring's children.

13 Oct 2021

Study identifies DNA mutations linking liver disease with obesity and diabetes

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

13 Oct 2021

CRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic regulation and functional effects

Oncotarget published "Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing" which reported that the adequate functioning of this process is indispensable for tissue homeostasis and cell fate determination.

11 Oct 2021

An investigation of SARS-CoV-2 infection in diabetic pregnancies

Researchers discuss the basic and clinical science of the potential inter-relationships between diabetes mellitus and COVID-19 in pregnancies.

11 Oct 2021

Researchers identify new biomarker for severe COVID-19

During the pandemic, it has become increasingly evident that people with cardiovascular disease and obesity are at a much higher risk of developing very severe, even fatal COVID-19 disease.

8 Oct 2021

High fat diet exacerbates Alzheimer's disease in mouse model

Research has shown that individuals who have diabetes are more prone to develop dementia. Although people are widely aware of diabetes, owing to its common occurrence, they are less aware of prediabetes. Similar to diabetes, prediabetes is also associated with impaired glucose tolerance. However, unlike diabetes, patients with prediabetes show a slight increase in insulin and fasting blood glucose rather than hyperglycemia.

7 Oct 2021

Study: Youth with type1 diabetes who use insulin pumps less likely to develop diabetic retinopathy

In one of the largest and most racially diverse studies to date of American children and adolescents with type 1 and type 2 diabetes, researchers at Johns Hopkins Medicine, Baylor College of Medicine and the University of Wisconsin have identified the clinical and demographic factors associated with pediatric diabetic retinopathy.

7 Oct 2021

Managing metabolic disease through time-restricted eating

In this interview, News-Medical speaks to Dr. Satchin Panda about his latest research into time-restricted eating and how it can be used to manage metabolic diseases.

5 Oct 2021

Study reveals the underlying mechanisms behind obesity and type 2 diabetes link

It is well known that obesity affects the body's insulin production and over time risks leading to type 2 diabetes and several other metabolic diseases.

4 Oct 2021

COVID-19 may trigger hyperglycemia by disrupting key metabolic signals to cause severe disease

COVID-19 may bring high risks of severe disease and death in many patients by disrupting key metabolic signals and thereby triggering hyperglycemia, according to a new study from researchers at Weill Cornell Medicine and NewYork-Presbyterian.

2 Oct 2021

WHO's new List of Essential Medicines prioritizes access to diabetes and cancer treatments

WHO today published the new edition of its Model Lists of Essential Medicines and Essential Medicines for Children, which include new treatments for various cancers, insulin analogues and new oral medicines for diabetes, new medicines to assist people who want to stop smoking, and new antimicrobials to treat serious bacterial and fungal infections.

1 Oct 2021

UVA researchers identify 14 genes that cause obesity

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain. The findings pave the way for treatments to combat a health problem that affects more than 40% of American adults.

1 Oct 2021

Additional supportive care services benefit older adults receiving chemotherapy, study finds

A clinical trial led by researchers at City of Hope, a world-renowned cancer research and treatment organization, showed that patients over 65 receiving chemotherapy experienced significantly fewer treatment-related side effects when a multidisciplinary team of experts analyzed each case and introduced personalized interventions.

30 Sep 2021

JDRF announces new grant to explore methods to alleviate diabetes distress

JDRF, the leading global nonprofit funder of type 1 diabetes (T1D) research, announces a new grant awarded to Albert Einstein College of Medicine and Montefiore Health System. Led by endocrinologist Shivani Agarwal, M.D., M.P.H., and by psychologist Jeffrey Gonzalez, Ph.D., the study will utilize telemedicine to deliver cognitive behavioral therapy to young adults with T1D to reduce diabetes-related distress.

30 Sep 2021

Scientists link insulin resistance to increased risk of developing major depressive disorder

Stanford Medicine scientists have linked insulin resistance to an increased risk of developing a major depressive disorder.

29 Sep 2021

Artificial sweeteners in drinks may increase food cravings and appetite, study reveals

A synthetic aftertaste might not be the only side effect of switching to diet soda, especially if you're trying to lose weight.

28 Sep 2021

Widely used osteoporosis drug protects against type 2 diabetes, says research

New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD), held online this year, suggests that the widely used osteoporosis drug alendronate reduces the risk of type 2 diabetes.

27 Sep 2021

Insulin resistance is associated with stroke, T2D study finds

A study of more than 100,000 people with type 2 diabetes (T2D), presented at the annual meeting of the European Association for the Study of Diabetes (EASD), held online this year, found that insulin resistance is associated with stroke.

27 Sep 2021

Ozone exposure linked to the development of Type 2 diabetes

Older Californians who live in communities with poor air quality, even those who engage - as recommended - in physical activities but do so outdoors, have a higher risk of Type 2 diabetes, a complex and chronic metabolic disorder caused by insulin resistance and cell dysfunction.

24 Sep 2021

Early weight loss may protect future fertility of young boys with obesity

Reproductive function in boys with obesity may be improved through weight loss, which could protect their fertility in adulthood, according to research presented today at the 59th Annual European Society for Paediatric Endocrinology Meeting.

23 Sep 2021