Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Artificial pancreas may soon help patients with type 2 diabetes

An artificial pancreas could soon help people living with type 2 diabetes and who also require kidney dialysis. Tests led by the University of Cambridge and Inselspital, University Hospital of Bern, Switzerland, show that the device can help patients safely and effectively manage their blood sugar levels and reduce the risk of low blood sugar levels.

4 Aug 2021

Research group identifies 15 novel biomarkers linked to late-onset dementias

A study by an international research group identified 15 novel biomarkers that are linked to late-onset dementias. These biomarkers are proteins, which predict cognitive decline and subsequent increased risk of dementia already 20 years before the disease onset.

3 Aug 2021

First interchangeable biosimilar insulin product approved by FDA for treatment of diabetes

Today, the U.S. Food and Drug Administration approved the first interchangeable biosimilar insulin product, indicated to improve glycemic control in adults and pediatric patients with Type 1 diabetes mellitus and in adults with Type 2 diabetes mellitus.

28 Jul 2021

Largest genetic study identifies new drug targets to treat type 1 diabetes

Scientists have completed the largest and most diverse genetic study of type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.

22 Jul 2021

Novel method for glucagon delivery to help individuals living with Type 1 diabetes

For children with Type 1 diabetes, the risk of experiencing a severe hypoglycemic episode is especially common -- and for parents, the threat of that happening in the middle of the night is especially frightening.

20 Jul 2021

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases

An internal transporter that enables us to use the copper we consume in foods like shellfish and nuts to enable a host of vital body functions also has the essential role of protecting the receptor that enables us to grow new blood vessels when ours become diseased, Medical College of Georgia scientists report.

20 Jul 2021

Biden’s July executive order includes drug pricing provisions. But will they do enough?

President Joe Biden's executive order of July 9 included various steps toward making good on campaign promises to take on pharmaceutical companies by allowing the importation of prescription drugs and curbing the high cost of medicines.

19 Jul 2021

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

The National Institutes of Health has awarded the University of South Florida total expected funds of $69.9 million over the next four years to continue the follow-up of study participants in The Environmental Determinants of Diabetes in The Young (TEDDY) consortium.

13 Jul 2021

Strawberries could improve cardiometabolic risk factors in at-risk adults

Whole berries have long been known for their extended health benefits. This has largely been due to their high fiber and polyphenol profile, as well as their low energy (calorie) contributions to daily diets.

8 Jul 2021

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Scientists at the University of Cambridge have identified rare genetic variants - carried by one in 3,000 people - that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect.

7 Jul 2021

Fecal transplant and fiber supplementation can benefit patients with obesity-related metabolic syndrome

A transplant of healthy gut microbes followed by fiber supplements benefits patients with severe obesity and metabolic syndrome, according to University of Alberta clinical trial findings published today in Nature Medicine.

6 Jul 2021

Study evaluates the difference in weight loss caused by two antidiabetic medications

Patients with Type 2 diabetes who were prescribed SGLT2 inhibitors lost more weight than patients who received GLP-1 receptor agonists, according to a University at Buffalo-led study.

2 Jul 2021

Study shows effects of COVID-19 pandemic on the health of women aged 50 to 70 years

In a study involving 34 women aged 50-70, researchers at the University of São Paulo (USP) in Brazil performed objective measurements of the impact on the subjects' health of the decrease in physical activity observed during the period of social distancing and isolation imposed by COVID-19.

30 Jun 2021

Scientists outline new target for treating type 2 diabetes

This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition.

30 Jun 2021

Study investigates the link between skeletal muscle proteome and type 2 diabetes

Globally, more than 400 million people have diabetes, most of them suffering from type 2 diabetes.

29 Jun 2021

Lowering iron content in fat cells prevented mice from gaining excess weight

Lowering iron content in fat cells prevented mice fed a high-fat diet from gaining excess weight and developing associated health problems by limiting the amount of lipids absorbed by the intestines, UT Southwestern scientists report in a new study. The findings, published online in Cell Metabolism, could eventually lead to new strategies to protect people against obesity and related diseases.

29 Jun 2021

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

A new review article published in the journal Antibiotics reports the presence of a large number of bioactive compounds in microalgae that target chemical structures present only in their structure.

28 Jun 2021

Study examines effect of sorafenib in patients with advanced hepatocellular carcinoma

Oncotarget published "Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib" which reported that this study investigated the association of the IGF/CTP score with overall survival and progression-free survival of HCC patients treated with sorafenib.

28 Jun 2021

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

Oncotarget published "Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells" which reported that to guide studies in cancer patients, relacorilant, an investigational selective GR modulator that antagonizes cortisol activity, was assessed in various tumor types, with multiple cytotoxic combination partners, and in the presence of physiological cortisol concentrations.

28 Jun 2021

New positive data on BCG’s ability to safely and significantly lower blood sugars

At the recent 2021 Annual Scientific Sessions of the American Diabetes Association, researchers from Massachusetts General Hospital (MGH) presented positive updates on their trials of the bacillus Calmette-Guérin (BCG) vaccine to safely and significantly lower blood sugars.

25 Jun 2021

Insulin News and Research

Further Reading

Artificial pancreas may soon help patients with type 2 diabetes

Research group identifies 15 novel biomarkers linked to late-onset dementias

First interchangeable biosimilar insulin product approved by FDA for treatment of diabetes

Largest genetic study identifies new drug targets to treat type 1 diabetes

Novel method for glucagon delivery to help individuals living with Type 1 diabetes

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases

Biden’s July executive order includes drug pricing provisions. But will they do enough?

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

Strawberries could improve cardiometabolic risk factors in at-risk adults

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Fecal transplant and fiber supplementation can benefit patients with obesity-related metabolic syndrome

Study evaluates the difference in weight loss caused by two antidiabetic medications

Study shows effects of COVID-19 pandemic on the health of women aged 50 to 70 years

Scientists outline new target for treating type 2 diabetes

Study investigates the link between skeletal muscle proteome and type 2 diabetes

Lowering iron content in fat cells prevented mice from gaining excess weight

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

Study examines effect of sorafenib in patients with advanced hepatocellular carcinoma

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

New positive data on BCG’s ability to safely and significantly lower blood sugars

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