Precision Medicine News and Research

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Researchers identify axitinib as promising candidate to treat drug-resistant leukaemia

A study led by researchers at the Institute for Molecular Medicine Finland FIMM and Faculty of Medicine, University of Helsinki and the Helsinki University Central Hospital Comprehensive Cancer Center, in close collaboration with researchers at Pfizer, has identified a previously unrecognized action of Pfizer's axitinib as a potent inhibitor of the dominant mutation that confers drug resistance to all well tolerated treatments in patients with certain types of leukemia.

10 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Study explores cost-effectiveness of targeted treatment for cancer

Health economics helps insurers, health care systems and providers make treatment decisions based on the cost of extra "units" of health arising from a specific treatment.

9 Feb 2015

Personalized prevention, treatments of cancer now accessible through Stanford University's new genetics course

Instrumental research that aims to enhance how we predict, diagnose and design personalized prevention and treatments of cancer is now accessible through Stanford University's latest professional education course, Understanding Cancer at the Genetic Level.

9 Feb 2015

Researchers offer critical new information about head and neck squamous cell cancer

Head and neck squamous cell cancer (HNSCC) ranks among the top ten most prevalent cancers in the United States. Despite its prevalence, little is known about how this cancer develops and spreads. However, in a paper published in the January 29, 2015 edition of Nature, researchers offer critical new information about head and neck cancers.

4 Feb 2015

New initiative aims at reducing adverse effects of medications in individuals with mental illnesses

Geneticists at the University of Pittsburgh Graduate School of Public Health will provide their scientific expertise to a new initiative aimed at preventing and reducing the adverse effects of medications in people with mental illnesses.

4 Feb 2015

Accelerated Cure Project for MS launches nationwide initiative to fuel multiple sclerosis research

The Accelerated Cure Project for Multiple Sclerosis today launches iConquerMS, the nationwide initiative by and for individuals living with multiple sclerosis who recognize the power of their health data and insights and want to harness that power to fuel research.

3 Feb 2015

Pancreatic Cancer Action Network praises President Obama for new Precision Medicine Initiative

"The Pancreatic Cancer Action Network applauds President Obama for his new Precision Medicine Initiative, and for making an important investment to advance cancer research and arm the scientific and medical community with the cutting edge tools and resources needed to fight cancer. This is especially welcome news for patients fighting pancreatic cancer who face a five-year survival rate of just seven percent.

31 Jan 2015

Immunotherapy expert discusses the concept of precision immunology and personalized medicine

With President Obama's recent State of the Union speech addressing the launch of a national precision medicine initiative to further tackle cancer and other diseases, a leading immunotherapy expert from Rutgers Cancer Institute of New Jersey weighs in on where we stand with precision immunology and personalized medicine and what needs to be accomplished.

30 Jan 2015

Novel technique could help identify cancerous tissue during brain tumor surgery

A novel radioguided surgery technique could quickly and effectively identify residual cancer cells during brain tumor surgery, with low radiation exposure for both patients and surgeons. The study, featured in the January 2015 issue of the Journal of Nuclear Medicine, reports that Y-90 DOTATOC, a beta-minus-emitting tracer, can effectively delineate the margins of meningiomas and high-grade gliomas.

28 Jan 2015

Yale researcher receives 2015 Frontiers of Knowledge Award in Biomedicine

A Spanish foundation has awarded a major scientific prize to Yale researcher Joseph Schlessinger and two colleagues in recognition of their work leading to the first personalized treatments for cancer. The 2015 Frontiers of Knowledge Award in Biomedicine from the Madrid-based BBVA Foundation includes a €400,000 cash prize.

27 Jan 2015

NovellusDx presents data from studies on Precision Cancer Analysis platform at PMWC 2015

NovellusDx, the leading Precision Cancer Analysis company delivering actionable intelligence about the mutational hierarchies that drive each patient’s cancer progression, announced today that the company will highlight data from studies on its Precision Cancer Analysis platform, at the Personalized Medicine World Conference 2015 in Silicon Valley.

27 Jan 2015

Dr. Hans Clevers receives ISSCR's McEwen Award for Innovation

The International Society for Stem Cell Research has awarded Dr. Hans Clevers, senior author on two important papers published recently in the scientific journal Cell, the society's McEwen Award for Innovation.

23 Jan 2015

Cleveland Clinic researcher awarded grant to advance treatment of lethal prostate cancer

The Prostate Cancer Foundation has presented Nima Sharifi, M.D., Kendrick Family Endowed Chair for Prostate Cancer Research at Cleveland Clinic's Lerner Research Institute, a Challenge Award to advance the treatment of lethal prostate cancer. He is also co-investigator on a second Challenge Award that was also selected for funding.

23 Jan 2015

Study identifies gene that may become resistant to current testicular cancer treatments

A major research study has uncovered several new genetic mutations that could drive testicular cancer - and also identified a gene which may contribute to tumours becoming resistant to current treatments.

22 Jan 2015

Cornell scientists develop new computational method to identify functional human genome

Striving to unravel and comprehend DNA's biological significance, Cornell University scientists have created a new computational method that can identify positions in the human genome that play a role in the proper functioning of cells, according to a report published Jan. 19 in the journal Nature Genetics.

22 Jan 2015

Research leads to new, better way to combat drug-resistant cancers

A team of researchers at Massachusetts General Hospital has developed a new platform that can rapidly identify effective drug combinations for lung cancer patients whose tumors have stopped responding to targeted therapy. The research, which was supported in part by the National Foundation for Cancer Research, is a critical milestone on the road to personalized medicine.

22 Jan 2015

Personalized approaches to treating intellectual disability

Scientists from the Florida campus of The Scripps Research Institute have produced an approach that protects animal models against a type of genetic disruption that causes intellectual disability, including serious memory impairments and altered anxiety levels.

22 Jan 2015

Luminex's xMAP Biothreat Toxin Panel now available for detecting dangerous biotoxins

Quickly detecting and identifying dangerous biotoxins is now a reality, thanks to the xMAP Biothreat Toxin Panel (BTP) by Luminex. The xMAP Biothreat Toxin Panel is the first multiplex assay to rapidly detect and identify the six most easily acquired and most dangerous biotoxins. All six of these biotoxins are on the US government's list of most dangerous substances.

From Luminex 21 Jan 2015

UChicago researchers awarded NIH grants to develop novel medications for sleep apnea, asthma

Two research teams based at the University of Chicago have received prestigious grants from the National Institutes of Health to develop novel medications to treat sleep apnea and asthma.

21 Jan 2015

Precision Medicine News and Research

Researchers identify axitinib as promising candidate to treat drug-resistant leukaemia

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Study explores cost-effectiveness of targeted treatment for cancer

Personalized prevention, treatments of cancer now accessible through Stanford University's new genetics course

Researchers offer critical new information about head and neck squamous cell cancer

New initiative aims at reducing adverse effects of medications in individuals with mental illnesses

Accelerated Cure Project for MS launches nationwide initiative to fuel multiple sclerosis research

Pancreatic Cancer Action Network praises President Obama for new Precision Medicine Initiative

Immunotherapy expert discusses the concept of precision immunology and personalized medicine

Novel technique could help identify cancerous tissue during brain tumor surgery

Yale researcher receives 2015 Frontiers of Knowledge Award in Biomedicine

NovellusDx presents data from studies on Precision Cancer Analysis platform at PMWC 2015

Dr. Hans Clevers receives ISSCR's McEwen Award for Innovation

Cleveland Clinic researcher awarded grant to advance treatment of lethal prostate cancer

Study identifies gene that may become resistant to current testicular cancer treatments

Cornell scientists develop new computational method to identify functional human genome

Research leads to new, better way to combat drug-resistant cancers

Personalized approaches to treating intellectual disability

Luminex's xMAP Biothreat Toxin Panel now available for detecting dangerous biotoxins

UChicago researchers awarded NIH grants to develop novel medications for sleep apnea, asthma

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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