Neurodegenerative Disease News and Research

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New glaucoma risk assessment principles help physicians decide who needs treatment

A new approach for assessing glaucoma risk factors could be the first step in helping ophthalmologists determine the risk of progression from ocular hypertension to glaucoma and blindness, according to an article published today in the September issue of the American Journal of Ophthalmology.

14 Sep 2004

Study on RNAi technology targeting neurodegenerative diseases

Sirna Therapeutics has announced the publication of preclinical studies evaluating RNA interference-based therapies for a class of inherited neurodegenerative diseases of the central nervous system (CNS) in the current issue of Nature Medicine.

16 Aug 2004

Effects of Huntington's disease mutation more complex than originally thought

Competing theories about why brain cells die in Huntington's disease may not be competitors after all, according to a report published July 21, 2004, in the online edition of the Annals of Neurology.

22 Jul 2004

Researchers shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease

CNRS and Inserm research scientists at the Institut Curie have shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease.

8 Jul 2004

Gene therapy may provide a treatment for a group of incurable, progressive neurological diseases called polyglutamine-repeat diseases

Researchers from the University of Iowa have have shown for the first time that gene therapy delivered to the brains of living mice can prevent the physical symptoms and neurological damage caused by an inherited neurodegenerative disease that is similar to Huntington's disease (HD).

5 Jul 2004

Parkinson's disease breakthrough

Brandeis scientists have made groundbreaking advances in understanding how the regulations of a novel gene during the cell cycle can lead to a rare familial case of the early onset of Parkinson's disease.

5 Jun 2004

Protein that appears to play a key role in Alzheimer's disease

A protein that allows human cancer to resist multiple anticancer drugs also appears to play a key role in Alzheimer's disease, according to research conducted at Fox Chase Cancer Center. The protein, active in brain tissue, could be a target for new drugs to treat patients with Alzheimer's.

20 May 2004

Tooth cells may help treat Parkinson's disease

Cells derived from the inside of a tooth might someday prove an effective way to treat the brains of people suffering from Parkinson's disease.

4 May 2004

Potential new drug may slow the progression of the Parkinson's disease

An international team of Parkinson's disease researchers has shown that a potential new drug is effective at treating patients in the early stages of Parkinson's and may even slow the progression of the disease. The results from the Parkinson Study Group are in the April 19 issue of the Archives of Neurology.

22 Apr 2004

New drug is effective at treating patients in the early stages of Parkinson’s

An international team of Parkinson’s disease researchers has shown that a potential new drug is effective at treating patients in the early stages of Parkinson’s and may even slow the progression of the disease.

20 Apr 2004

Curry offers possible protection against Alzheimer’s disease

A new study has found that curry, a common and popular cooking additive, could be an effective enhancer of an enzyme that protects the brain against oxidative conditions.

19 Apr 2004

Identification of first protein biomarkers to help patients with amyotrophic lateral sclerosis

A University of Pittsburgh pathologist has identified the first protein biomarkers able to diagnose patients with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease) with near 100 percent accuracy. Before this finding, there were no known diagnostic biomarkers for this neurodegenerative disease.

18 Apr 2004

Scientists discover gene for Parkinson's disease

UCL scientists have discovered a new gene implicated in the early development of Parkinson's disease. In a study of families with early onset disease, Professor Nick Wood and colleagues at University College London's Institute of Neurology identified a novel gene which produces a malfunctioning protein that could pave the way for new treatments for Parkinson sufferers.

16 Apr 2004

New Theory About Alzheimer's Disease

A group of scientists at The Scripps Research Institute has proposed a new theory about the cause of Alzheimer's disease, the progressive neurodegenerative disorder that currently afflicts some 4.5 million Americans. According to the hypothesis, the disease arises as a consequence of inflammation, which creates abnormal metabolites out of normal brain molecules.

22 Mar 2004