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Novel synthetic DNA vaccine induces protective immunity against MERS virus in animal study

A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

21 Aug 2015

Researchers identify strategy to prevent adenoviruses from multiplying and causing sickness in humans

Using an animal model they developed, Saint Louis University and Utah State university researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans.

21 Aug 2015

FDA accepts Allergan's resubmission of BOTOX sBLA for treatment of adults with upper limb spasticity

Allergan plc, a leading global pharmaceutical company today announced that the U.S. Food and Drug Administration has accepted the company's resubmission of its Supplemental Biologics License Application (sBLA) for BOTOX (onabotulinumtoxinA) for the treatment of adults with lower limb (involving ankle and toe muscles) spasticity in adults.

20 Aug 2015

Discovery provides new insights into how asthma may be caused

Researchers from the University of Leicester and University Hospitals of Leicester NHS Trust, working with the National Institute of Allergy and Infectious Diseases and Genentech, have discovered new insights into how asthma may be caused, by identifying three distinct groups of asthma patients characterised by the activity of different genes in an individual's airways.

20 Aug 2015

Discovery could influence future research on respiratory failure associated with diabetes

Previous studies have shown that diabetes adversely affects breathing and respiratory function. However, in the past, researchers have not differentiated diaphragm muscle cells and the muscle cells of limb skeletal muscle in their studies. Now, researchers from the University of Missouri have found that diaphragm muscle cells and other skeletal muscle cells behave differently--a finding that could influence future research on respiratory ailments associated with diabetes.

20 Aug 2015

Kentucky, Oklahoma and Rhode Island researchers awarded NSF grant to develop innovative brain imaging technologies

The National Science Foundation has awarded $6 million to researchers in Kentucky, Oklahoma and Rhode Island to develop innovative and broadly accessible brain imaging technologies to provide insight into how the nervous system functions in health and disease.

20 Aug 2015

Experimental MERS-CoV vaccine shows promise in monkeys and camels

National Institutes of Health scientists and colleagues report that an experimental vaccine given six weeks before exposure to Middle East respiratory syndrome coronavirus (MERS-CoV) fully protects rhesus macaques from disease. The vaccine also generated potentially protective MERS-CoV antibodies in blood drawn from vaccinated camels.

20 Aug 2015

Hospira announces TGA approval of Inflectra (infliximab) for treatment of eight inflammatory conditions

Hospira today announced that Inflectra (infliximab), the first monoclonal antibody (mAb) biosimilar therapy, has been registered in Australia. This registration paves the way for the Federal Government to reduce the cost of some of the most expensive medicines on the Pharmaceutical Benefits Scheme (PBS).

20 Aug 2015

E-cigarettes becoming more widely available in developing countries

Most of the debate around e-cigarettes has focused on the developed world, but the devices are becoming more widely available in some low- and middle-income countries, where there is even greater potential for impact on public health, say two Stanford University School of Medicine researchers.

19 Aug 2015

Journal articles on yoga therapy increase 3-fold in last 10 years

During the last 10 years, the number of articles in peer-reviewed journals worldwide about clinical trials of yoga therapy to alleviate disease-related symptoms increased 3-fold. This large-scale analysis of published research studies spanning 46 years, 29 countries, and more than 28,000 study participants is published in The Journal of Alternative and Complementary Medicine, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

18 Aug 2015

U-M microbiome research may lead to new ways to prevent, fight lung infections in patients

With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Researchers at the University of Michigan Medical School have started to answer these questions by studying the microbiome of the lungs - the community of microscopic organisms that are in constant contact with our respiratory system.

18 Aug 2015

New OTEMTO phase three results show potential improvement to quality of life for COPD patients

Boehringer Ingelheim announced the publication of new data from the Phase IIIb OTEMTO® 1&2 trials (NCT01964352/NCT02006732), which show Spiolto® Respimat® (tiotropium/olodaterol) provides consistent, clinically meaningful improvements in quality of life versus placebo in patients with COPD

17 Aug 2015

FDA accepts Chiasma's NDA filing for octreotide capsules for treatment of adult patients with acromegaly

Chiasma, Inc., a U.S. late-stage biopharmaceutical company, today announced that the U.S. Food and Drug Administration has accepted for filing the Company's New Drug Application (NDA) for the marketing and sale of octreotide capsules, an oral drug proposed for the maintenance therapy of adult patients with acromegaly.

17 Aug 2015

Unituxin (dinutuximab) granted EC Marketing Authorisation for treatment of childhood neuroblastoma

United Therapeutics Corporation announced today that the European Commission (EC) has granted Marketing Authorisation for Unituxin (dinutuximab) for the treatment of high-risk neuroblastoma in patients aged 12 months to 17 years, who have previously received induction chemotherapy and achieved at least a partial response, followed by myeloablative therapy and autologous stem cell transplantation (ASCT).

17 Aug 2015

Breastfeeding may lead to substantial reduction in common infections among Indigenous babies

Promoting breastfeeding could lead to a substantial reduction in common infections and even deaths that are more common in Indigenous infants than non-Indigenous infants, a new study suggests.

17 Aug 2015

Anti-smoking laws lead to decrease in stillbirths

Stillbirths have dropped by almost eight per cent in England since the smoking ban was introduced, research shows.

14 Aug 2015

MGH papers reveal the way anesthetics affect brains of older patients and children

Recent Massachusetts General Hospital (MGH) investigations into the neurobiology underlying the effects of general anesthesia have begun to reveal the ways different anesthetic agents alter specific aspects of the brain's electrical signals, reflected by EEG (electroencephalogram) signatures. While those studies have provided information that may lead to improved techniques for monitoring the consciousness of patients receiving general anesthesia, until now they have been conducted in relatively young adult patients.

14 Aug 2015

BDSI announces FDA approval of sNDA for new formulation of ONSOLIS (fentanyl buccal soluble film) CII

BioDelivery Sciences International, Inc. announced the approval by the U.S. Food and Drug Administration of a Supplemental New Drug Application (sNDA) for a new formulation of ONSOLIS (fentanyl buccal soluble film) CII for the management of breakthrough pain in patients with cancer who are opioid tolerant.

13 Aug 2015

USciences professor provides infection control measures for college-bound students

Thousands of students across Greater Philadelphia will soon start the next chapter of their lives as they begin their college journeys away from home.

13 Aug 2015

UNMCC receives NCI Comprehensive Cancer Center designation for cancer treatment, research programs

The University of New Mexico Cancer Center has been awarded the highest designation and rating in the United States for cancer treatment and research programs. It has received the National Cancer Institute's "NCI Comprehensive Cancer Center" designation, identifying it as one of the leading cancer centers in the nation and the only such cancer center in New Mexico.

13 Aug 2015

Respiratory News and Research

Novel synthetic DNA vaccine induces protective immunity against MERS virus in animal study

Researchers identify strategy to prevent adenoviruses from multiplying and causing sickness in humans

FDA accepts Allergan's resubmission of BOTOX sBLA for treatment of adults with upper limb spasticity

Discovery provides new insights into how asthma may be caused

Discovery could influence future research on respiratory failure associated with diabetes

Kentucky, Oklahoma and Rhode Island researchers awarded NSF grant to develop innovative brain imaging technologies

Experimental MERS-CoV vaccine shows promise in monkeys and camels

Hospira announces TGA approval of Inflectra (infliximab) for treatment of eight inflammatory conditions

E-cigarettes becoming more widely available in developing countries

Journal articles on yoga therapy increase 3-fold in last 10 years

U-M microbiome research may lead to new ways to prevent, fight lung infections in patients

New OTEMTO phase three results show potential improvement to quality of life for COPD patients

FDA accepts Chiasma's NDA filing for octreotide capsules for treatment of adult patients with acromegaly

Unituxin (dinutuximab) granted EC Marketing Authorisation for treatment of childhood neuroblastoma

Breastfeeding may lead to substantial reduction in common infections among Indigenous babies

Anti-smoking laws lead to decrease in stillbirths

MGH papers reveal the way anesthetics affect brains of older patients and children

BDSI announces FDA approval of sNDA for new formulation of ONSOLIS (fentanyl buccal soluble film) CII

USciences professor provides infection control measures for college-bound students

UNMCC receives NCI Comprehensive Cancer Center designation for cancer treatment, research programs

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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