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Researchers produce insulin-secreting cells from stem cells of diabetic patients

Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes.

11 May 2016

Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

Researchers at Tufts University have stabilized blood samples for long periods of time without refrigeration and at high temperatures by encapsulating them in air-dried silk protein.

11 May 2016

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Scientists in Manchester, who have developed a stem cell gene therapy to reverse a fatal childhood illness, have agreed to work with a new therapeutics company to test it in a human trial.

11 May 2016

Graphene flakes can modulate synapses

The laboratory of SISSA's Laura Ballerini in collaboration with the University of Trieste, the University of Manchester and the University of Castilla -la Mancha, has discovered a new approach to modulating synapses.

11 May 2016

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

In Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons.

11 May 2016

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

A study by scientists at the University of Glasgow, which reveals the critical role a common cancer-associated gene plays in lymphoma development, could lead to improved treatments for a range of cancers.

11 May 2016

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

St. Jude Children's Research Hospital scientists have used sophisticated pharmacologic modeling and simulation to translate preclinical findings into a successful phase I clinical trial of a chemotherapy agent for treatment of ependymoma. The research marked the first time the approach has been used to calculate drug doses for a clinical trial in pediatric brain tumor patients.

10 May 2016

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics.

10 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

A new study on the epigenetics of lactose intolerance may provide an approach to understanding schizophrenia and other complex, serious illnesses

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

MGH researchers develop device to rapidly diagnose health-care-associated infections

A team of Massachusetts General Hospital investigators has developed a device with the potential of shortening the time required to rapidly diagnose pathogens responsible for health-care-associated infections from a couple of days to a matter of hours.

10 May 2016

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas.

10 May 2016

Caltech researchers discover new potential cause for Crohn's disease

The community of beneficial bacteria that live in our intestines, known as the gut microbiome, are important for the development and function of the immune system. There has been growing evidence that certain probiotics--therapies that introduce beneficial bacteria into the gut--may help alleviate some of the symptoms of intestinal disorders such as Crohn's disease.

10 May 2016

School children participate in The Next Big Thing Challenge at Siemens offices in Frimley

Pupils had 3 months to come up with solutions to a variety of high level challenges faced in the healthcare environment and UK market. The challenge encourages Key Stage 4 students to find out more about the world of engineering and technology.

9 May 2016

UAB hospital leads the way in improving antibiotic use

One of today's urgent health threats is antibiotic resistance, caused by inappropriate prescription and use of antibiotics, and — according to the Centers for Disease Control and Prevention — approximately 50 percent of all antibiotics prescribed in the United States are unnecessary or inappropriate, with many of them prescribed in inpatient settings.

9 May 2016

Controlling heart cells using a laser: an interview with Prof. Konstantin Agladze

We control their electrical activity. Cardiac cells are capable of producing and transmitting electric signals through changes in a cell membrane potential.

9 May 2016

Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

University of Toronto Assistant Professor of Pharmacy Keith Pardee and an international team of collaborators, including scientists from the Wyss Institute at Harvard University, have developed a low-cost, easy-to-use diagnostic platform for detecting the Zika virus.

9 May 2016

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known as microcephaly. Now, for the first time, researchers at University of California San Diego School of Medicine have determined one way Zika infection can damage developing brain cells.

9 May 2016

Unique attributes of zebrafish may help study human blood disorders

Genetic regulation of the various types of blood cells in zebrafish and humans is highly similar, making it relatively easy and cost-effective to perform genetic, chemical, imaging and other molecular studies on this invaluable model organism to study normal hematopoetic development in humans as well as blood disorders and malignancies, as described in a Review article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

9 May 2016

Laboratory News and Research

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Graphene flakes can modulate synapses

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

MGH researchers develop device to rapidly diagnose health-care-associated infections

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Caltech researchers discover new potential cause for Crohn's disease

School children participate in The Next Big Thing Challenge at Siemens offices in Frimley

UAB hospital leads the way in improving antibiotic use

Controlling heart cells using a laser: an interview with Prof. Konstantin Agladze

Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

Unique attributes of zebrafish may help study human blood disorders

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