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Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Researchers emphasize that an effective vaccine should induce mucosal immunity and prevent the nasal entry of SARS-CoV-2.

27 Oct 2021

Study uncovers how novel coronavirus disrupts normal cell defenses to hijack human host cells

A UBC-led research team has uncovered how the virus responsible for causing COVID-19 escapes destruction in infected cells, allowing SARS-CoV-2 to persist and continue spreading in the human body.

27 Oct 2021

Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

Researchers in the United States have conducted a study showing that Moderna’s coronavirus disease 2019 (COVID-19) vaccine provided durable protection against the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus macaques.

26 Oct 2021

Identification of long COVID patients using big data

A new preprint exploits big data to come up with some answers as to the incidence, treatment, and impact on healthcare systems of long covid.

26 Oct 2021

Health care costs for people with rare diseases have been underestimated, study shows

A new, retrospective study of medical and insurance records indicates health care costs for people with a rare disease have been underestimated and are three to five times greater than the costs for people without a rare disease.

22 Oct 2021

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Amidst growing concerns on the use and potential benefits of convalescent plasma therapy, a research group in the United States has identified three human antibodies (Abs) that, when combined, demonstrate both robust viral suppressive properties against all tested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Variants of Concern (VoC) in vitro and profound antiviral efficacy in vivo.

22 Oct 2021

Booster dose of COVID-19 vaccine significantly increases neutralizing antibodies in rhesus macaques

A booster dose of the mRNA-1273 COVID-19 vaccine given to rhesus macaques about six months after their primary vaccine series significantly increased levels of neutralizing antibodies against all known SARS-CoV-2 variants of concern, according to a new study from National Institutes of Health scientists and colleagues.

21 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

20 Oct 2021

The neutralization potential of nanobodies against SARS-CoV-2

A recent review describes the role of nanobodies as a new class of recombinant antibodies that are used in the treatment of COVID-19.

20 Oct 2021

Scientists search for cause of mysterious covid-related inflammation in children

Like most other kids with covid, Dante and Michael DeMaino seemed to have no serious symptoms.

20 Oct 2021

E-cigarette use does not help smokers successfully stay off cigarettes, study says

The United States Centers for Disease Control and Prevention have suggested that smokers who are unable to quit smoking may benefit by switching from smoking cigarettes to vaping e-cigarettes if they switch completely and are able to avoid relapsing to cigarette smoking.

19 Oct 2021

New AI-based computer algorithm may enable quicker diagnosis of heart failure

A special artificial intelligence (AI)-based computer algorithm created by Mount Sinai researchers was able to learn how to identify subtle changes in electrocardiograms (also known as ECGs or EKGs) to predict whether a patient was experiencing heart failure.

19 Oct 2021

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

In a recent study published in the journal PLOS Pathogens, scientists showed that nasal administration of a single-domain antibody (VHH), named K-874A, brought about inhibition of SARS-CoV-2 titers in infected lungs of Syrian hamsters.

19 Oct 2021

New research focuses on better understanding of lupus in Black women

Nine out of 10 patients with systemic lupus erythematosus -; the autoimmune disease also known as SLE -; are females.

18 Oct 2021

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

To address the gaps in the knowledge, a team of researchers from the University of California and the Gladstone Institute of Virology conducted 39-parameter phenotyping by cytometry by time of flight (CyTOF) on 33 longitudinal specimens from 11 mRNA-vaccinated individuals, of which six had previously been infected and recovered from COVID-19.

18 Oct 2021

Lungs News and Research

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Study uncovers how novel coronavirus disrupts normal cell defenses to hijack human host cells

Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

Identification of long COVID patients using big data

Health care costs for people with rare diseases have been underestimated, study shows

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Booster dose of COVID-19 vaccine significantly increases neutralizing antibodies in rhesus macaques

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

The neutralization potential of nanobodies against SARS-CoV-2

Scientists search for cause of mysterious covid-related inflammation in children

E-cigarette use does not help smokers successfully stay off cigarettes, study says

New AI-based computer algorithm may enable quicker diagnosis of heart failure

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

New research focuses on better understanding of lupus in Black women

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

Common treatment for MIS-C patients likely works by depleting neutrophils

Global progress in tackling tuberculosis has been reversed by the COVID-19 pandemic

SARS-CoV-2 induces tissue immune memory

COVID-19 linked to newborn complications

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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