Receptor News and Research

RSS

Gene linked to both alcoholism and depression

A national team of investigators led by psychiatric geneticists at Washington University School of Medicine in St. Louis has identified a gene that appears to be linked to both alcoholism and depression.

8 Sep 2004

Bird flu has jumped species barrier to cats

Now the United Nations health agency is investigating reports that bird flu, which experts say could mutate into a potentially deadly human pandemic under certain conditions, has now jumped the species barrier to infect cats.

4 Sep 2004

Women over 70 are safe to not have radiation treatment after heaving a lumpectomy

Two new studies reported in The New England Journal of Medicine suggest that older women with breast cancer are safe to not have radiation treatment after heaving a lumpectomy.

1 Sep 2004

International research sheds light on Escherichia coli

An unprecedented picture of how bacteria latch on to human cells has been published by UK, French and US scientists. They have produced a finely detailed model of one of the tools used by some of the nastiest varieties of the stomach bug, Escherichia coli, to stick to and gain entry to host cells.

1 Sep 2004

Study is the first comprehensive risk analysis to examine both the risk of death from breast cancer and other causes following diagnosis

Women who are diagnosed with breast cancer at a young age, or at an advanced stage at any age, are more likely to die from the disease than from all other causes of death combined, according to a new study by scientists at the National Cancer Institute.

1 Sep 2004

Study suggests that patients with pulmonary arterial hypertension may benefit from Thelin therapy

Encysive Pharmaceuticals today announced the presentation of data from a clinical study of Thelin(TM) (sitaxsentan) in pulmonary arterial hypertension (PAH), at the European Society of Cardiology Annual Congress in Munich.

31 Aug 2004

Angina drug nifedipine safe for long-term use

Calcium antagonists such as nifedipine are used to relieve the symptoms of angina, but there have been doubts about their long-term safety. However, ACTION--A Coronary disease Trial Investigating Outcome with Nifedipine GITS--provides new information on the drug's long-term use. GITS (gastrointestinal therapeutic system) modifies the release of the drug to provide stable long-term concentrations of nifedipine in blood.

30 Aug 2004

New study confirms benefits of rimonabant in weight loss

Phase III clinical study comparing placebo to rimonabant, the first agent in a new therapeutic class known as selective cannabinoid type 1 (CB1) blockers, showed that overweight or obese people taking rimonabant 20mg once daily benefited from a significant reduction in their body weight

29 Aug 2004

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Human Genome Sciences has begun dosing patients in a Phase 1 clinical trial of HGS-TR2J, a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies.

25 Aug 2004

Blueberries may lower cholesterol

New research from the U.S. Department of Agriculture shows that blueberries may lower cholesterol as effectively as a commercial drug and have the potential for fewer adverse side effects.

23 Aug 2004

Genmab's HuMax-CD4 receives U.S. orphan drug designation

Genmab has announced that HuMax-CD4 for the treatment of Mycosis Fungoides (MF), which constitutes 75% of all Cutaneous T-cell Lymphomas (CTCL), has been designated an orphan drug by the US Food and Drug Administration (FDA). The US prevalence of MF is estimated at 16,000 to 20,000.

23 Aug 2004

Novel disease mechanism underlying rheumatoid arthritis

Investigators at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) have identified a novel disease mechanism underlying rheumatoid arthritis that may open the door to new therapies for this and other debilitating autoimmune disorders.

23 Aug 2004

Genetic mutation link to sudden infant death syndrome

Researchers at Rush University Medical Center, and colleagues at the University of Pittsburgh have identified mutations in genes pertinent to the autonomic nervous system among babies who died of sudden infant death syndrome (SIDS) that might explain why they died.

21 Aug 2004

Zinc plays a crucial role in blindness

Dartmouth Medical School researchers in their quest to find cures for inherited diseases have found that zinc plays a crucial role in blindness in over one million people worldwide.

18 Aug 2004

Newly discovered protein switch may be key to understanding sleep disorders, anxiety, and depression

University of California researchers have found that a newly discovered protein switch which they named neuropeptide S appears to work in the brain to enhance wakefulness and reduce anxiety in laboratory animals. According to Rainer Reinscheid and his colleagues, the protein could help in the understanding of sleep disorders, anxiety, and depression.

18 Aug 2004

New guidelines urge early and long-term treatment with Aldosterone blockade therapy

Patients who have had a recent heart attack with ST-elevation (ST-Elevation Myocardial Infarction, or STEMI), complicated by heart failure should be treated with aldosterone blockers according to new guidelines issued recently by the American College of Cardiology (ACC) and the American Heart Association (AHA).

17 Aug 2004

Receptor News and Research

Gene linked to both alcoholism and depression

Bird flu has jumped species barrier to cats

Women over 70 are safe to not have radiation treatment after heaving a lumpectomy

International research sheds light on Escherichia coli

Study is the first comprehensive risk analysis to examine both the risk of death from breast cancer and other causes following diagnosis

Study suggests that patients with pulmonary arterial hypertension may benefit from Thelin therapy

Angina drug nifedipine safe for long-term use

New study confirms benefits of rimonabant in weight loss

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Blueberries may lower cholesterol

Genmab's HuMax-CD4 receives U.S. orphan drug designation

Novel disease mechanism underlying rheumatoid arthritis

Genetic mutation link to sudden infant death syndrome

Zinc plays a crucial role in blindness

Newly discovered protein switch may be key to understanding sleep disorders, anxiety, and depression

New guidelines urge early and long-term treatment with Aldosterone blockade therapy

Drug developers should take a different approach to snake venom and heart medications

Relationship between brain chemical messenger glutamate and schizophrenia traits

Receptor for estrogen in ovarian cells has been shown to suppress tumor growth

Gene responsible for management of glutamate is a promising candidate in determining risk for schizophrenia

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Latest News