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U of T researchers develop new approach for controlling neuron generation in Parkinson's disease

Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective treatments.

30 Apr 2024

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

National Institutes of Health researchers and collaborators have discovered over 100 new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure.

30 Apr 2024

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

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30 Apr 2024

Psychedelic compound shows promise in stress relief for socially aggressive mice

A study in Neuropharmacology reveals that a single dose of the psychedelic compound (R)-DOI significantly improves stress-coping behaviors and reduces inflammatory markers in mice subjected to social aggression.

30 Apr 2024

UK study confirms healthy habits can extend lifespan, even with genetic predispositions

The associations between lifestyle, genetic factors, and human longevity.

29 Apr 2024

Cinnamon, curcumin, and resveratrol show promise in diabetes inflammation fight

Researchers reviewed the impact of cinnamon, curcumin, and resveratrol on oxidative stress and inflammation in type 2 diabetes patients, highlighting their potential to improve metabolic regulation and reduce complications.

26 Apr 2024

New research lays foundation for targeted therapies to inhibit NF-κB activation

A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit activation of nuclear factor kappa B (NF-κB), a transcription factor that plays a role in various autoimmune and inflammatory diseases and cancers.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Study links acid-reducing drugs to increased risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice, an official journal of the American Academy of Neurology.

24 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Innovative peptide-based hydrogel therapy for virus prevention

Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop.

23 Apr 2024

U-M scientists develop new tool to better understand neuronal signaling

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons.

23 Apr 2024

New tool hunts for Alzheimer's clues in gut microbiome

Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.

23 Apr 2024

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

A review in Current Research in Food Science explores how bioactive compounds in coffee, tea, and cocoa combat obesity by inhibiting white adipogenesis and promoting brown adipogenesis and lipolysis.

22 Apr 2024

Young mouse plasma found to reverse aging in older mice

Researchers demonstrate that small extracellular vesicles (sEVs) from young mice plasma can reverse aging effects in older mice by enhancing mitochondrial function and energy metabolism.

22 Apr 2024

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

The role of neighborhood-level disparities in determining shorter breast cancer-specific survival.

22 Apr 2024

Study links air pollution to increased colorectal cancer risk through DNA changes

Researchers reveal how air pollution increases colorectal cancer (CRC) risk through epigenetic changes, using a large-scale study and Mendelian randomization to demonstrate ambient pollution’s impact on CRC mortality and incidence in China.

21 Apr 2024

Animal study suggests early Western diet exposure linked to lasting memory issues

Researchers find that early exposure to a Western diet in rats leads to long-lasting impairments in hippocampus-dependent memory, mediated by disruptions in acetylcholine signaling.

18 Apr 2024

Receptor News and Research

U of T researchers develop new approach for controlling neuron generation in Parkinson's disease

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

Psychedelic compound shows promise in stress relief for socially aggressive mice

UK study confirms healthy habits can extend lifespan, even with genetic predispositions

Cinnamon, curcumin, and resveratrol show promise in diabetes inflammation fight

New research lays foundation for targeted therapies to inhibit NF-κB activation

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Study links acid-reducing drugs to increased risk of migraine

Prostaglandin E2: The culprit behind tumor immune evasion

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Innovative peptide-based hydrogel therapy for virus prevention

U-M scientists develop new tool to better understand neuronal signaling

New tool hunts for Alzheimer's clues in gut microbiome

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

Young mouse plasma found to reverse aging in older mice

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

Study links air pollution to increased colorectal cancer risk through DNA changes

Animal study suggests early Western diet exposure linked to lasting memory issues

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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