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Ruthigen, Pulmatrix sign definitive merger agreement

Ruthigen, Inc., a biopharmaceutical company, and Pulmatrix, Inc., a Lexington, Massachusetts based clinical stage biotechnology company, announced today that on March 13, 2015, they have entered into a definitive merger agreement.

16 Mar 2015

Meta-analysis finds that high dose zinc acetate lozenges may help reduce duration of cold symptoms

According to a meta-analysis published in BMC Family Practice, high dose zinc acetate lozenges shortened the duration of common-cold associated nasal discharge by 34%, nasal congestion by 37%, scratchy throat by 33%, and cough by 46%.

16 Mar 2015

Exposure to diesel exhaust may exacerbate respiratory diseases

Researchers in the UK have, for the first time, shown how exhaust pollution from diesel engines is able to affect nerves within the lung. Air pollution is a significant threat to health, they say, and identifying potential mechanisms linking exposure to diesel exhaust and the exacerbation of respiratory diseases may lead to treatments for those affected.

16 Mar 2015

Antibiotic nanoparticles can help treat lung infection, prevent drug resistance

Treating respiratory disease is often difficult because drugs have to cross biological barriers such as respiratory tissue and mucosa, and must therefore be given in large quantities in order for an effective amount to reach the target.

13 Mar 2015

Gottlieb Allergy Count kicks off its first report of 2015

Those in the Midwest with sensitive respiratory systems will find relief beginning Monday, March 16 as the Gottlieb Allergy Count kicks off its first report of 2015. The Gottlieb Allergy Count is the official daily allergy count for the Midwest.

13 Mar 2015

TRMC expands use of capnography to monitor patients during moderate sedation

Tillamook Regional Medical Center recently strengthened patient safety measures by expanding its use of capnography to monitor patients during moderate sedation. Sedation is commonly used during procedures such as colonoscopies and in some instances can suppress breathing.

12 Mar 2015

More research needed to explore toxicity of cellulose nanocrystals, says Virginia Tech scientist

Are cellulose nanocrystals harmful to human health? The answer might depend on the route of exposure, according to a review of the literature by a Virginia Tech scientist, but there have been few studies and many questions remain.

12 Mar 2015

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that affects approximately 200,000 people a year in the United States and has a higher mortality rate than breast and prostate cancer combined. The condition most often occurs in people who are critically ill or who have significant injuries; those who do survive it often experience profound skeletal muscle weakness.

12 Mar 2015

Repeatedly exposing children to secondhand smoke is child abuse, argues Adam Goldstein

Purposefully and repeatedly exposing children to secondhand smoke — a known human carcinogen — is child abuse, according to an opinion piece written by Adam Goldstein, MD, MPH, a professor in the Department of Family Medicine at the University of North Carolina School of Medicine.

11 Mar 2015

$Study evaluates effectiveness of surgical vs nonsurgical treatment for proximal humeral fractures$

Study evaluates effectiveness of surgical vs nonsurgical treatment for proximal humeral fractures

Among patients with a displaced fracture in the upper arm near the shoulder (proximal humeral), there was no significant difference between surgical treatment and nonsurgical treatment in patient-reported outcomes over two years following the fracture, results that do not support the trend of increased surgery for patients with this type of fracture, according to a study in the March 10 issue of JAMA.

10 Mar 2015

Inhaled Nitric Oxide still being used in preterm neonates despite evidence of short-term benefit

Inhaled Nitric Oxide (iNO) is a drug approved by the Food and Drug Administration that is commonly used in term and near-term neonates who have severe respiratory failure caused by pulmonary hypertension. Over the last decade there have been multiple large studies trying to determine a clinical use for iNO in preterm neonates, but despite evidence of short-term benefit, this drug has not been shown to improve long-term outcomes in preemies.

10 Mar 2015

Halyard Health releases improved placement kit for PEG tube

Halyard Health, formerly Kimberly-Clark Health Care, today announced the introduction of an improved placement kit for its Percutaneous Endoscopic Gastrostomy (PEG) tube, the MIC* PEG tube. The components of the kit have been organized to align with the procedural steps for tube placement.

9 Mar 2015

Blood gas testing: an interview with David Stein, PhD, CEO, Point of Care, Siemens Healthcare Diagnostics

The industry term ‘blood gas testing’ has come to mean the accurate measurement and reporting of a wide menu of blood parameters, all on a single platform.

From Siemens Healthineers Point of Care Diagnostics 9 Mar 2015

FDA approves Astellas' CRESEMBA for treatment of invasive aspergillosis, invasive mucormycosis

Astellas today announced that the U.S. Food and Drug Administration has approved its New Drug Application (NDA) for the use of CRESEMBA (isavuconazonium sulfate), the prodrug for isavuconazole, for patients 18 years of age and older in the treatment of invasive aspergillosis and invasive mucormycosis (also known as zygomycosis).

8 Mar 2015

Adults only really catch flu about twice a decade, suggests study

Adults over the age of 30 only catch flu about twice a decade, a new study suggests. Flu-like illness can be caused by many pathogens, making it difficult to assess how often people are infected by influenza.

6 Mar 2015

Preventing lung infections in childhood could help people with cystic fibrosis during adulthood

Preventing lung infections in childhood could stop later life-threatening infections for people with cystic fibrosis (CF), according to the latest research carried out at Aston University.

6 Mar 2015

European launch of the Proxima miniature in-line blood gas analyser at ISICEM 2015

Sphere Medical, innovator in critical care monitoring and diagnostics equipment, will launch its ground-breaking in-line patient dedicated arterial blood gas analyser in Germany, Netherlands and Belgium at ISICEM 2015.

5 Mar 2015

Mallinckrodt enters into definitive agreement to acquire Ikaria

Mallinckrodt plc, a leading global specialty biopharmaceutical company, and Ikaria, Inc. a privately-held critical care company, announced today that they have entered into a definitive agreement under which a subsidiary of Mallinckrodt will acquire Ikaria, Inc. from a Madison Dearborn-led investor group in a transaction valued at approximately $2.3 billion.

5 Mar 2015

Symbiomix Therapeutics announces positive results from SYM-1219 Phase 1 clinical program

Symbiomix Therapeutics, a late-stage, privately held biopharmaceutical company developing innovative medicines for serious women's health infections, today announced results from its Phase 1 clinical program demonstrating that its lead product candidate, SYM-1219, was safe and well tolerated and had predictable pharmacokinetics (PK), and that contraceptive efficacy for birth control pills would not be altered by SYM-1219 administration.

4 Mar 2015

Reducing premature deaths from noncommunicable diseases: an interview with Dr Shanthi Mendis, WHO

The main types of NCD are cardiovascular disease, cancer, chronic respiratory diseases and diabetes. These have been identified as the principal conditions for three main reasons. One is that, collectively, they contribute the most to the total disease burden.

4 Mar 2015

Respiratory News and Research

Ruthigen, Pulmatrix sign definitive merger agreement

Meta-analysis finds that high dose zinc acetate lozenges may help reduce duration of cold symptoms

Exposure to diesel exhaust may exacerbate respiratory diseases

Antibiotic nanoparticles can help treat lung infection, prevent drug resistance

Gottlieb Allergy Count kicks off its first report of 2015

TRMC expands use of capnography to monitor patients during moderate sedation

More research needed to explore toxicity of cellulose nanocrystals, says Virginia Tech scientist

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Repeatedly exposing children to secondhand smoke is child abuse, argues Adam Goldstein

Study evaluates effectiveness of surgical vs nonsurgical treatment for proximal humeral fractures

Inhaled Nitric Oxide still being used in preterm neonates despite evidence of short-term benefit

Halyard Health releases improved placement kit for PEG tube

Blood gas testing: an interview with David Stein, PhD, CEO, Point of Care, Siemens Healthcare Diagnostics

FDA approves Astellas' CRESEMBA for treatment of invasive aspergillosis, invasive mucormycosis

Adults only really catch flu about twice a decade, suggests study

Preventing lung infections in childhood could help people with cystic fibrosis during adulthood

European launch of the Proxima miniature in-line blood gas analyser at ISICEM 2015

Mallinckrodt enters into definitive agreement to acquire Ikaria

Symbiomix Therapeutics announces positive results from SYM-1219 Phase 1 clinical program

Reducing premature deaths from noncommunicable diseases: an interview with Dr Shanthi Mendis, WHO

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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