Laboratory News and Research

RSS

New gene cut-and-paste methods help correct disease-causing mutation in animal model

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.

3 Feb 2016

UAB research explores neurofibromatosis type 1

It is easy to tell a medical research story that has a simple and dramatic moment. But disease is often much more complex, and the work to understand it can be painstaking. A vivid example of that is seen in the University of Alabama at Birmingham Medical Genomics Laboratory, headed by Ludwine Messiaen, Ph.D., professor of genetics. This lab offers clinical genetic testing for a broad array of common and rare genetic disorders.

3 Feb 2016

New drug cocktail may show promise in NSCLC patients

A drug approved by the Food and Drug Administration for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

3 Feb 2016

New article provides guidance on managing critically ill patients at risk for alcohol withdrawal

Alcohol withdrawal adds challenges to caring for critically ill patients, and nurses must be diligent at each stage of care to minimize complications, according to an article in the February issue of Critical Care Nurse.

3 Feb 2016

Study provides new insights into breast cancer metastasis

It has long been thought that cancer metastasizes, or spreads, when a single cancer cell escapes from the original tumor, travels through the bloodstream and sets up shop in distant organs. However, a growing body of evidence suggests that these bad actors don't travel alone; instead they migrate through the body in cellular clusters, like gangs.

2 Feb 2016

Rockland announces availability of new human melanoma cell lines

Rockland Immunochemicals, Inc. announces the availability of a new collection of human melanoma cell lines that have been developed and characterized over several decades in the laboratory of Meenhard Herlyn, D.V.M., D.Sc., Caspar Wistar Professor in Melanoma Research, Director of the Melanoma Research Center, and professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute in Philadelphia.

1 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

UW–Madison center continues to offer accurate radiation treatment

As radiation sources used to map disease and attack cancer grow in number and complexity, a University of Wisconsin-Madison center continues to offer the last word on accurate radiation doses.

1 Feb 2016

FedMed gains access to Trovagene's Precision Cancer Monitoring tests and service

Trovagene, Inc., a developer of cell-free molecular diagnostics, announced today that it has entered into an agreement with FedMed, Inc. establishing health benefit access to Trovagene's full line of Precision Cancer Monitoring (PCM) tests and services.

1 Feb 2016

Newcastle University scientists use seaweed extract to develop 'Stem-gell' bandage for wound healing

Publishing in STEM CELLS Translational Medicine Professor Che Connon and Dr Stephen Swioklo describe the low-cost seaweed solution.

1 Feb 2016

Bile acid enables foetus to produce blood stem cells

A research group at Lund University in Sweden has been able to show that bile acid is transferred from the mother to the foetus via the placenta to enable the foetus to produce blood stem cells.

31 Jan 2016

Study provides vital information about mechanisms governing DNA repair

DNA damage can lead to gene inactivation or deregulation and cause various diseases such as cancer; however, many DNA repair mechanisms allow cells to survive against such damage. A study lead by Antoine Simoneau of the laboratory of Dr. Hugo Wurtele, a researcher in immunology-oncology at the Maisonneuve-Rosemont Hospital (CIUSS de l'Est-de-l'Île-de-Montréal) and professor at the Faculty of Medicine, University of Montreal, and recently published in the prestigious journal Nucleic Acids Research, provides valuable information about certain mechanisms governing DNA repair.

31 Jan 2016

Ocean acidification affecting population demography, adaptation potential of marine species

Ocean acidification may be impacting upon the population dynamics of marine species and hindering their ability to genetically adapt to future climate change.

30 Jan 2016

FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

In laboratory neuronal cultures, an FDA-approved drug used to treat high blood pressure reduced cell damage often linked to Alzheimer's disease, say researchers at Georgetown University Medical Center and the National Institutes of Health.

30 Jan 2016

MGH study may lead to first nonsurgical treatment for seborrheic keratoses

An investigation into the molecular mechanisms responsible for the most common type of benign skin lesion may lead to the first nonsurgical treatment for the growths called seborrheic keratoses (SKs), which in addition to being cosmetically unattractive are often worrisome to patients.

30 Jan 2016

TSRI scientists reveal workings of key 'relief-valve' in cells

A team led by scientists at The Scripps Research Institute has solved a long-standing mystery in cell biology by showing essentially how a key "relief-valve" in cells does its job.

30 Jan 2016

UCL-led researchers find way to assess viability of induced pluripotent stem cells

A research team led by scientists from UCL have found a way to assess the viability of 'manufactured' stem cells known as induced pluripotent stem cells (iPSCs). Published today in Nature Communications, the team's discovery offers a new way to fast-track screening methods used in stem cell research.

30 Jan 2016

Brain's natural plasticity could compensate for inner ear damage

Researchers from Massachusetts Eye and Ear/Harvard Medical School have described, for the first time, the adult brain's ability to compensate for a near-complete loss of auditory nerve fibers that link the ear to the brain. The findings, published in the current issue of Neuron, suggest that the brain's natural plasticity can compensate for inner ear damage to bring sound detection abilities back within normal limits; however, it does not recover speech intelligibility.

29 Jan 2016

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai Inc. announced today that the U.S. Food and Drug Administration approved Halaven (eribulin mesylate) Injection (0.5 mg per mL) for the treatment of patients with unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen.

29 Jan 2016

Researchers developing new methods to better analyze effects of e-cig flavorings

Faculty and student researchers at Rochester Institute of Technology's National Technical Institute for the Deaf are developing methods to better analyze the effects of flavorings used in electronic cigarettes (e-cigs).

29 Jan 2016

Laboratory News and Research

New gene cut-and-paste methods help correct disease-causing mutation in animal model

UAB research explores neurofibromatosis type 1

New drug cocktail may show promise in NSCLC patients

New article provides guidance on managing critically ill patients at risk for alcohol withdrawal

Study provides new insights into breast cancer metastasis

Rockland announces availability of new human melanoma cell lines

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

UW–Madison center continues to offer accurate radiation treatment

FedMed gains access to Trovagene's Precision Cancer Monitoring tests and service

Newcastle University scientists use seaweed extract to develop 'Stem-gell' bandage for wound healing

Bile acid enables foetus to produce blood stem cells

Study provides vital information about mechanisms governing DNA repair

Ocean acidification affecting population demography, adaptation potential of marine species

FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

MGH study may lead to first nonsurgical treatment for seborrheic keratoses

TSRI scientists reveal workings of key 'relief-valve' in cells

UCL-led researchers find way to assess viability of induced pluripotent stem cells

Brain's natural plasticity could compensate for inner ear damage

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Researchers developing new methods to better analyze effects of e-cig flavorings

Pittcon 2024 - Advancing Science on the West Coast eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Latest Life Science News