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Pharmacyclics wins 2014 Society for Medicines Research Award for Drug Discovery

Pharmacyclics, Inc. today announced that it has won the prestigious 2014 Society for Medicines Research Award for Drug Discovery for its discovery of ibrutinib (IMBRUVICA). The award was presented by The Society of Medicines Research at its biennial award lecture in Kensington, London.

4 Dec 2014

Tobacco smoke toxin could increase pain in people with spinal cord injury

A neurotoxin called acrolein found in tobacco smoke that is thought to increase pain in people with spinal cord injury has now been shown to accumulate in mice exposed to the equivalent of 12 cigarettes daily over a short time period.

4 Dec 2014

PulmoFlow's nebulized drug and device combination gets FDA approval for cystic fibrosis

On Tuesday, the FDA granted final approval of PulmoFlow, Inc.'s New Drug Application for Kitabis Pak – a co-packaging of generic tobramycin inhalation solution with a PARI LC PLUS Nebulizer. This is the first nebulized drug and device combination to be approved for patients with cystic fibrosis.

3 Dec 2014

Many pediatric chest X-rays unnecessary, offer no clinical benefit

Researchers at Mayo Clinic found that some children are receiving chest X-rays that may be unnecessary and offer no clinical benefit to the patient, according to a study presented today at the annual meeting of the Radiological Society of North America.

3 Dec 2014

Novartis to highlight advances in blood, breast cancer research at ASH and SABCS 2014

Novartis will highlight more than 250 abstracts demonstrating advances in blood and breast cancer research at the upcoming American Society of Hematology (ASH) annual meeting December 6-9, and CTRC-AACR San Antonio Breast Cancer Symposium (SABCS) December 9-13.

2 Dec 2014

Researchers identify infection control gaps as major culprit in spread of MERS-CoV

Little is known about the often fatal virus known as Middle East respiratory syndrome coronavirus (MERS-CoV), but researchers have identified gaps in infection control as a major culprit in all eleven published cases involving healthcare-associated transmission of the virus.

2 Dec 2014

Variants of ASIC1a gene appear to be associated with panic disorder

Panic disorder is a severe form of anxiety in which the affected individual feels an abrupt onset of fear, often accompanied by profound physical symptoms of discomfort. Scientists have known from studying twins that genes contribute to the risk of panic disorder, but very little is known about which specific genes are involved.

2 Dec 2014

Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

Eli Lilly and Company and AstraZeneca today announced enrollment of the first patient into AMARANTH, a Phase II/III study of an oral beta secretase cleaving enzyme (BACE) inhibitor currently in development as a potential treatment for Alzheimer's disease.

1 Dec 2014

Different forms of ASIC1a gene associated with panic disorder

Panic disorder is a severe form of anxiety in which the affected individual feels an abrupt onset of fear, often accompanied by profound physical symptoms of discomfort.

1 Dec 2014

Researchers dismiss causal link between antibiotics treatment and childhood asthma

In a new register study in the scientific journal BMJ, researchers at Karolinska Institutet are able to dismiss previous claims that there is a link between the increased use of antibiotics in society and a coinciding rise in childhood asthma. The study includes half a million children and shows that exposure to antibiotics during pregnancy or early in life does not appear to increase the risk of asthma.

1 Dec 2014

EMA accepts new IMBRUVICA (ibrutinib) application for treatment of Waldenstrom's macroglobulinemia

Pharmacyclics, Inc.today announced the acceptance of a Type II variation application for IMBRUVICA (ibrutinib) by the European Medicines Agency.

1 Dec 2014

Kessler Institute provides tips to help reduce risk of injury during winter months

Winter appears to have arrived early, bringing with it record snowfalls and cold temperatures across the country. It also brings an increased risk for injuries. Whether shoveling snow, dealing with icy roads, or simply trying to walk on wet, slippery pavement, caution is the key word.

29 Nov 2014

Study provides proof of concept for developing antibodies against human pathogens

Scientists investigating the potentially deadly hantavirus have used a novel approach to developing protective antibodies against it. Their work, published in today's online edition of Science Translational Medicine, provides proof of concept for producing antibodies against a broad range of human pathogens.

28 Nov 2014

Persistent eosinophilia common in COPD

More than one-third of patients with chronic obstructive pulmonary disease have persistent eosinophilia, researchers report in the European Respiratory Journal.

27 Nov 2014

electroCore CEO highlights the importance of working with stakeholders when launching new technologies

JP Errico, founder and CEO of electroCore, speaking at The FT Global Pharmaceutical and Biotechnology Conference in London last week, emphasized the importance of working with each of the major stakeholders, i.e., patients and their advocates, key opinion-leading physicians, and decision-makers within the payor community at the earliest opportunity, particularly in regards to innovative and disruptive technology such as electroCore’s non-invasive vagus nerve stimulation (nVNS).

26 Nov 2014

UTSA's Bernard Arulanandam named fellow of AAAS

Bernard Arulanandam, UTSA Jane and Roland Blumberg Professor in Biology and Assistant Vice President for Research Support, has been named a fellow of the American Association for the Advancement of Science. Arulanandam was elected by his peers for the honor, recognizing his scientific and socially distinguished efforts to advance science and its applications.

26 Nov 2014

Abnormal vitamin D, trace element levels may indicate asthma risk

Serum levels of vitamin D, copper and zinc could help identify infants with recurrent wheezing who are at risk of developing asthma, Turkish researchers suggest.

25 Nov 2014

Stable asthma prevalence masks increase in allergic phenotype

The prevalence of childhood asthma in Sweden appears to have stabilised, with no increase seen between 1996 and 2006, researchers report.

25 Nov 2014

Study shows effectiveness of VolitionRx’s NuQ test in detecting lung cancer in blood and sputum

VolitionRx Limited, a life sciences company focused on developing diagnostic tests for cancer and other conditions, today announced that data from its pilot lung cancer study will be presented at the Science for Business BioWin Day 2014, being held November 26, 2014 in Louvain-la-Neuve, Belgium.

25 Nov 2014

Endo announces acquisition of rights to Natesto (testosterone nasal gel)

Endo International plc, announced today the acquisition of rights to Natesto (testosterone nasal gel), the first and only testosterone nasal gel for replacement therapy in adult males diagnosed with hypogonadism, from Trimel BioPharma SRL, a wholly-owned subsidiary of Trimel Pharmaceuticals Corporation.

24 Nov 2014

Respiratory News and Research

Pharmacyclics wins 2014 Society for Medicines Research Award for Drug Discovery

Tobacco smoke toxin could increase pain in people with spinal cord injury

PulmoFlow's nebulized drug and device combination gets FDA approval for cystic fibrosis

Many pediatric chest X-rays unnecessary, offer no clinical benefit

Novartis to highlight advances in blood, breast cancer research at ASH and SABCS 2014

Researchers identify infection control gaps as major culprit in spread of MERS-CoV

Variants of ASIC1a gene appear to be associated with panic disorder

Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

Different forms of ASIC1a gene associated with panic disorder

Researchers dismiss causal link between antibiotics treatment and childhood asthma

EMA accepts new IMBRUVICA (ibrutinib) application for treatment of Waldenstrom's macroglobulinemia

Kessler Institute provides tips to help reduce risk of injury during winter months

Study provides proof of concept for developing antibodies against human pathogens

Persistent eosinophilia common in COPD

electroCore CEO highlights the importance of working with stakeholders when launching new technologies

UTSA's Bernard Arulanandam named fellow of AAAS

Abnormal vitamin D, trace element levels may indicate asthma risk

Stable asthma prevalence masks increase in allergic phenotype

Study shows effectiveness of VolitionRx’s NuQ test in detecting lung cancer in blood and sputum

Endo announces acquisition of rights to Natesto (testosterone nasal gel)

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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