Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

Besides being underweight, babies born to women whose diet lacked sufficient protein during pregnancy tend to have kidney problems resulting from alterations that occurred while their organs were forming during the embryonic stage of their development.

5 May 2021

Study investigates how Brd4 influences diet-induced obesity

A new study, published in JCI Insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity.

4 May 2021

Stomach-specific protein plays a key role in the progression of obesity

Scientists believe a stomach-specific protein plays a major role in the progression of obesity, according to new research in Scientific Reports.

4 May 2021

Researchers discover new way to improve the subcutaneous administration of mRNA

If not before, then certainly since the first messenger RNA (mRNA) vaccines to combat the SARS CoV2 virus were approved in Germany, mRNA has become a recognized term even outside scientific circles.

4 May 2021

FDA approves new drug for treatment of adults with chronic kidney disease

Today, the U.S. Food and Drug Administration approved Farxiga (dapagliflozin) oral tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression.

30 Apr 2021

Study examines risk phenotypes of diabetes and their association with COVID-19 severity

People with diabetes are at increased risk of developing a severe course of COVID-19 compared to people without diabetes.

29 Apr 2021

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases, is now recruiting patients for a Phase 2 clinical trial to investigate whether pills containing white button mushroom extract could regulate the immune system, affecting prostate-specific antigen (PSA) levels to either remain stable or decline.

29 Apr 2021

Pancreatic cancer cells de-differentiate to spawn highly aggressive tumors, study shows

A Ludwig Cancer Research study has identified a previously unrecognized mechanism by which cancer cells of a relatively benign subtype of pancreatic tumors methodically revert-or "de-differentiate"-to a progenitor, or immature, state of cellular development to spawn highly aggressive tumors that are capable of metastasis to the liver and lymph nodes.

29 Apr 2021

Processed diets may promote diseases characterized by low-grade infection and inflammation

Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

28 Apr 2021

Surge of pediatric patients with diabetic ketoacidosis during COVID-19 pandemic

According to the Centers for Disease Control and Prevention (CDC), children generally appear to be less severely impacted by COVID-19 than adults.

26 Apr 2021

Study may provide a basis for oral insulin development using DNP peptides

Researchers from Kumamoto University, Japan have found that DNP peptide, a small intestine-permeable cyclic peptide originally used as an insulin additive to improve absorption into the small intestinal, lowers blood glucose levels in mice.

26 Apr 2021

Study links muscle gene to type 2 diabetes

People with type 2 diabetes tend to have poorer muscle function than others. Now a research team at Lund University in Sweden has discovered that in type 2 diabetes, a specific gene is of great importance for the ability of muscle stem cells to create new mature muscle cells.

23 Apr 2021

Clinical trial examines metabolic effects of natural compound NMN in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.

22 Apr 2021

Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Shifts in care due to COVID-19 pandemic likely to drive drug expenditures in 2021

The COVID-19 pandemic heavily influenced spending on prescription drugs in the U.S. in 2020, according to the ASHP's (American Society of Health-System Pharmacists) National Trends in Prescription Drug Expenditures and Projections for 2021.

21 Apr 2021

New blood-based test detects lymph node metastasis in individuals with high-risk T1 colorectal cancer

Scientists at City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, have developed a novel, noninvasive liquid biopsy test for detecting lymph node metastasis in individuals with high-risk T1 colorectal carcinoma.

21 Apr 2021

Once-a-week injectable insulin therapy proves to be safe, effective in people with Type 2 diabetes

Treating people with Type 2 diabetes with a new once-a-week injectable insulin therapy proved to be safe and as effective as daily insulin injections, according to the results of two international clinical trials published online today in Diabetes Care.

19 Apr 2021

Insulin News and Research

Further Reading

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

Study investigates how Brd4 influences diet-induced obesity

Stomach-specific protein plays a key role in the progression of obesity

Researchers discover new way to improve the subcutaneous administration of mRNA

FDA approves new drug for treatment of adults with chronic kidney disease

Study examines risk phenotypes of diabetes and their association with COVID-19 severity

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

Pancreatic cancer cells de-differentiate to spawn highly aggressive tumors, study shows

Processed diets may promote diseases characterized by low-grade infection and inflammation

Surge of pediatric patients with diabetic ketoacidosis during COVID-19 pandemic

Study may provide a basis for oral insulin development using DNP peptides

Study links muscle gene to type 2 diabetes

Clinical trial examines metabolic effects of natural compound NMN in people

Novel approach to gene editing bypasses disease-causing mutations in a gene

Shifts in care due to COVID-19 pandemic likely to drive drug expenditures in 2021

New blood-based test detects lymph node metastasis in individuals with high-risk T1 colorectal cancer

Once-a-week injectable insulin therapy proves to be safe, effective in people with Type 2 diabetes

Five-year study aims to improve health of patients with cystic fibrosis across their growing lifespan

WHO’s new initiative aims to speed up action on diabetes

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

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