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Study examines glucocorticoid tapering in rheumatoid arthritis

Is the long-term use of glucocorticoids essential in people with chronic inflammatory diseases such as rheumatoid arthritis, or can early discontinuation prevent characteristic side effects?

31 Jul 2020

Novel vaccine candidate robustly protects non-human primates against SARS-CoV-2

The development of a safe and effective vaccine will likely be required to end the COVID-19 pandemic. A group of scientists, led by Beth Israel Deaconess Medical Center immunologist Dan H. Barouch, MD, PhD, now report that a leading candidate COVID-19 vaccine developed at BIDMC in collaboration with Johnson & Johnson raised neutralizing antibodies and robustly protected non-human primates against SARS-CoV-2, the virus that causes COVID-19.

30 Jul 2020

Pimavanserin reduced psychotic symptoms in people with dementia in phase 3 study

A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in people with dementia, a condition for which no treatments are currently licensed.

29 Jul 2020

Public health experts fear a hasty FDA signoff on vaccine

The vaccine trial that Vice President Mike Pence kicked off in Miami on Monday gives the United States the tiniest chance of being ready to vaccinate millions of Americans just before Election Day.

29 Jul 2020

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Researchers at Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation.

29 Jul 2020

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2, report scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. SARS-CoV-2 is the virus that causes COVID-19.

28 Jul 2020

Moderna coronavirus vaccine candidate moves to phase 3 with 30,000 participants

The world’s most significant coronavirus disease (COVID-19) vaccine study is underway in the United States, with a planned 30,000 volunteers. The phase 3 clinical trial aims to examine the efficacy and safety of the candidate vaccine developed by the National Institutes of Health and Moderna Inc.

28 Jul 2020

GW to participate in a clinical trial for investigational COVID-19 vaccine

The George Washington University today announced that it will participate in a clinical trial for an investigational COVID-19 vaccine.

27 Jul 2020

Brigham to play two key roles in phase 3 trial of COVID-19 vaccine candidate

A vaccine candidate for preventing COVID-19 is advancing to a 30,000-participant phase 3 trial that begins today, and Brigham and Women's Hospital will play two key roles in the trial's next phase.

27 Jul 2020

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

AI Therapeutics announced the start of Phase II clinical trial for the treatment of newly diagnosed COVID-19 patients in collaboration with Yale University.

27 Jul 2020

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

According to new research, the use of hydroxychloroquine among outpatients in clinical trials, without high-risk factors for cardiac arrhythmia, is safe.

27 Jul 2020

The color of COVID: Will vaccine trials reflect America’s diversity?

When U.S. scientists launch the first large-scale clinical trials for COVID-19 vaccines this summer, Antonio Cisneros wants to make sure people like him are included.

27 Jul 2020

National clinical trial to test potential vaccine against SARS-CoV-2

UC San Diego Health and the Altman Clinical and Translational Research Institute, part of UC San Diego School of Medicine, will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

25 Jul 2020

New study helps identify patients at higher risk of statin-related myopathy

Statins are prescribed to millions of people worldwide to reduce their risks of suffering heart attacks and strokes.

25 Jul 2020

Monthly vaginal ring moves one step closer to becoming a new HIV prevention method

A vaginal ring intended to be used for a month at a time has moved one step closer to potentially becoming a new HIV prevention method for cisgender women in sub-Saharan Africa, who despite being the face of the epidemic, have few options for protecting themselves against getting infected.

24 Jul 2020

Placebo News and Research

Study examines glucocorticoid tapering in rheumatoid arthritis

Novel vaccine candidate robustly protects non-human primates against SARS-CoV-2

Pimavanserin reduced psychotic symptoms in people with dementia in phase 3 study

Public health experts fear a hasty FDA signoff on vaccine

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Moderna coronavirus vaccine candidate moves to phase 3 with 30,000 participants

GW to participate in a clinical trial for investigational COVID-19 vaccine

Brigham to play two key roles in phase 3 trial of COVID-19 vaccine candidate

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

The color of COVID: Will vaccine trials reflect America’s diversity?

National clinical trial to test potential vaccine against SARS-CoV-2

New study helps identify patients at higher risk of statin-related myopathy

Monthly vaginal ring moves one step closer to becoming a new HIV prevention method

Fluoxetine does not improve brain recovery after acute stroke

Fusion protein may help treat pulmonary arterial hypertension

Mindfulness training helps reduce intimate partner violent behavior in men

UC Davis Health evaluates new antibody cocktail as a possible treatment for COVID-19

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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