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MGH scientists show how Shigella survives journey from mouth to the colon

Surviving the treacherous journey through the human body from the mouth to the colon takes a special kind of bacterial pathogen.

31 May 2017

Study: Type 2 diabetes linked to bacteria that penetrate mucus lining of the colon

In humans, developing metabolic disease, particularly type 2 diabetes, is correlated with having bacteria that penetrate the mucus lining of the colon, according to a study led by Drs. Benoit Chassaing and Andrew Gewirtz at Georgia State University.

30 May 2017

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research to be presented at the annual conference of the European Society of Human Genetics today (Monday).

29 May 2017

Researchers can attack cancer by working together, says UNC Charlotte professor

MUC1 is a protein present on the cells that line most organs. It lubricates and protects them. When cells become malignant, the MUC1 protein changes and signals tumor cells to multiply.

27 May 2017

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Novartis today announced the US Food and Drug Administration approved the expanded use of Zykadia (ceritinib) to include the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, as detected by an FDA-approved test.

27 May 2017

New study finds dramatic reorganization of the gut caused by weight loss surgery

Obesity, already a global epidemic, is on the rise. Over one-third of the U.S. population is currently afflicted, according to the Centers for Disease Control and the monetary costs alone are approaching $150 billion dollars annually.

26 May 2017

FDA grants accelerated approval to cancer treatment based on common biomarker

The U.S. Food and Drug Administration today granted accelerated approval to a treatment for patients whose cancers have a specific genetic feature (biomarker).

23 May 2017

Study shows new promise in the fight against pancreatic cancer

New research from the Keck School of Medicine of the University of Southern California shows new promise in the fight against one of the most lethal forms of cancer.

23 May 2017

New finding could lead to more effective treatment decisions for younger colorectal cancer patients

Younger colon cancer patients appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

18 May 2017

Colon cancer patients with healthy lifestyle have longer disease-free survival, study finds

A study of 992 patients with stage III colon cancer found that those who reported a healthy lifestyle during and following adjuvant (post-surgery) treatment had a 42% lower chance of death and a trend for lower chance of cancer recurrence than those who had less healthy lifestyles.

18 May 2017

Nut consumption reduces chance of colon cancer recurrence and death, study shows

An observational study of 826 patients with stage III colon cancer showed that those who consumed two ounces or more of nuts per week had a 42% lower chance of cancer recurrence and 57% lower chance of death than those who did not eat nuts.

18 May 2017

Regular exercise and good diet could reduce risk of disease recurrence, death in colon cancer patients

Colon cancer patients who have a healthy body weight, exercise regularly and eat a diet high in whole grains, fruits and vegetables have a significantly lower risk of cancer recurrence or death, according to a research team led by UC San Francisco investigators.

18 May 2017

Researchers identify new strategy that doubles screening rates for colorectal cancer

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a strategy that doubled screening rates for colorectal cancer, the second leading cause of cancer death in the United States, among patient groups who historically have had lower rates.

16 May 2017

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

Boosting a part of the immune system known to have anti-tumor properties may actually help tumors grow in cancers linked to chronic inflammation.

12 May 2017

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechanism that links the two phenomena.

11 May 2017

Studies pave way for genome-targeted treatments in pancreatic cancer

University of Pittsburgh and UPMC researchers are paving the way for genome-targeted treatments in pancreatic cancer, an especially deadly form of cancer with few existing therapeutic options, according to a pair of recent studies.

9 May 2017

Study reveals role of good-guy protein in initiating and maintaining cancer

Under normal conditions, the CHD4 protein is one of the good guys: it stops cells from transcribing faulty DNA, thereby eliminating potential mutation. But in colon cancer and perhaps other kinds of cancer as well, it appears that this protein becomes a kind of double agent, working for the enemy.

9 May 2017

Individuals who follow healthy lifestyle less likely to have colorectal cancer risk, survey finds

A Cleveland Clinic colon cancer risk assessment survey found that respondents who exercised more followed a healthy diet and did not smoke were less likely to have a personal history of colorectal cancer or colon polyps.

8 May 2017

Advanced endoscope to enable rapid, accurate diagnosis of early colon cancer

Minimally invasive endoscope using breakthrough photonics technology to enable rapid, accurate diagnosis of bowel polyps and early colon cancer.

5 May 2017

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Despite intense research, there's been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell proliferation activator, a duality that has caused a great deal of scientific head scratching.

5 May 2017

Colon News and Research

MGH scientists show how Shigella survives journey from mouth to the colon

Study: Type 2 diabetes linked to bacteria that penetrate mucus lining of the colon

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Researchers can attack cancer by working together, says UNC Charlotte professor

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

New study finds dramatic reorganization of the gut caused by weight loss surgery

FDA grants accelerated approval to cancer treatment based on common biomarker

Study shows new promise in the fight against pancreatic cancer

New finding could lead to more effective treatment decisions for younger colorectal cancer patients

Colon cancer patients with healthy lifestyle have longer disease-free survival, study finds

Nut consumption reduces chance of colon cancer recurrence and death, study shows

Regular exercise and good diet could reduce risk of disease recurrence, death in colon cancer patients

Researchers identify new strategy that doubles screening rates for colorectal cancer

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

Studies pave way for genome-targeted treatments in pancreatic cancer

Study reveals role of good-guy protein in initiating and maintaining cancer

Individuals who follow healthy lifestyle less likely to have colorectal cancer risk, survey finds

Advanced endoscope to enable rapid, accurate diagnosis of early colon cancer

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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