Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

New saliva-based HIV test gives results in 20 minutes!

The usual waiting period for the results of a HIV test can seem like an eternity, especially in emergency situations where results are needed immediately. Also it requires a blood sample, which is invasive and often painful. Recognizing the urgent need for a faster and less invasive diagnostic method, Dr. Nitika Pant Pai, from Marina Klein's research team at the MUHC has just finished testing a new saliva-based test that gives results in approximately 20 minutes! She describes her findings in an article that will appear in the May 6th, 2008 issue of PLoS Medicine.

6 May 2008

First sequence-based map of large-scale structural variation across the human genome

A nationwide team of researchers, funded in part by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has produced the first sequence-based map of large-scale structural variation across the human genome. The work, published today in the journal Nature, provides a starting point to examine how such DNA variation contributes to human health and disease.

30 Apr 2008

Human protein may offer novel target for blocking HIV infection

A research group supported by the National Institutes of Health (NIH) has uncovered a new route for attacking the human immunodeficiency virus (HIV) that may offer a way to circumvent problems with drug resistance. In findings published today in the online edition of the Proceedings of the National Academy of Sciences, the researchers report that they have blocked HIV infection in the test tube by inactivating a human protein expressed in key immune cells.

29 Apr 2008

New route discovered for attacking the human immunodeficiency virus

28 Apr 2008

Involving partners of pregnant women in Africa to improve AIDS prevention

According to the World Health Organization, nearly three-quarters of the world's 40 million human immunodeficiency virus (HIV)-infected people are living in Sub-Saharan Africa. Sixty-five per cent of the 4.3 million infected in 2006 caught the virus in this part of the world where women are particularly at risk.

28 Apr 2008

New insight into the pathogenesis of neurodegeneration in Ataxia telangiectasia

An upcoming paper from Dr. David Wassarman (University of Wisconsin School of Medicine and Public Health) in the May 1 issue of G&D lends new insight into the pathogenesis of neurodegeneration in Ataxia telangiectasia.

15 Apr 2008

Discovery of gene involved in blood stem cell replication, movement

Researchers at the Joslin Diabetes Center have identified a gene that is responsible for the division and movement of marrow-derived, blood-forming stem cells, a finding that could have major implications for the future of bone marrow and blood cell transplantation.

10 Apr 2008

Researchers identify gene involved in blood stem cell replication, movement

10 Apr 2008

Researchers discover how HIV can hide in cells

Researchers have discovered how Human Immunodeficiency Virus (HIV), which causes AIDS, can hide itself in our cells and dodge the attention of our normal defences, scientists heard at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre.

1 Apr 2008

AIDS, an evolutionary accident?

AIDS, a fatal disease in humans, may partly be the consequence of an evolutionary accident, scientists heard at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre.

1 Apr 2008

Scientists discover how salmonella becomes lethal for AIDS patients

Nearly half of all HIV-positive African adults who become infected with Salmonella die from what otherwise would be a seven-day bout of diarrhea.

25 Mar 2008

New understanding of rare immune disorder called Job's syndrome

Scientists have made another major breakthrough--the second in the past year--in understanding a rare immune disorder called Job's syndrome.

18 Mar 2008

Anadis licenses antibody technologies from ImmuCell

Anadis Limited, an Australian-based biotechnology company focused on milk derived polyclonal antibodies and other milk-derived bioactives, announced today that it had signed a final agreement with ImmuCell Corporation, a biotechnology company headquartered in Portland, Maine, USA.

11 Mar 2008

Understanding primate evolution could aid HIV research

Evolution moves in fits and starts, shaping species through random genetic mutations that can help them survive or even hasten their death.

28 Feb 2008

25% of HIV infected women want to become pregnant

About one in four women who have tested positive for the human immunodeficiency virus (HIV) expect pregnancy and motherhood to be a part of their future, recent research suggests.

26 Feb 2008

Genetic defect causes immune deficiency and balance disorder

A genetic defect that causes a severe immune deficiency in humans may also produce balance disorders, according to a new study by researchers at the University of Iowa, The Jackson Laboratory and East Carolina University.

21 Feb 2008

Stereotypes and misinformation about HIV still commonplace in healthcare

The doctor who wouldn't come into the patient's hospital room. The neurologist who avoided eye contact. The ambulance attendant who angrily threw her bloodied gloves into the street after learning the injured patient was HIV-positive.

20 Feb 2008

Risk factors for severe RSV infection in immunocompromised children

St. Jude Children's Research Hospital investigators and collaborators have shown how to predict if a child who is infected with respiratory syncytial virus (RSV) while being treated for cancer or another catastrophic disease is at high risk for developing severe infection. The finding will help clinicians improve guidelines for managing these infected children.

4 Feb 2008

New anti-HIV medication etravirine shows great promise

The AIDS Institute, a national public policy research, advocacy, and education organization, is encouraged with the FDA's approval of the first new non-nucleoside reverse transcriptase inhibitor (NNRTI) in nearly a decade.

4 Feb 2008

Debate over safety of gene therapy trials focuses on issue of informed consent

Can a patient who agrees to participate in a safety study of a gene therapy protocol give truly informed consent and understand the risks involved when the consent forms are highly technical and the physician or institution seeking their consent has a stake in the study and its outcome?

23 Jan 2008