Respiratory News and Research

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Docs who treat patients with severe LAM face agonizing treatment decision

Doctors who treat patients with a severe and progressive respiratory disease called lymphangioleiomyomatosis (LAM) can face an agonizing treatment decision.

18 Apr 2014

OPKO Health enters into definitive agreement to acquire Inspiro Medical

OPKO Health, Inc. has entered into a definitive agreement to acquire Inspiro Medical Ltd., an Israeli medical device company developing a new platform to deliver small molecule drugs such as corticosteroids and beta agonists or larger molecules to treat respiratory diseases. Inspiro's Inspiromatic is a "smart" easy-to-use dry powder inhaler with several advantages over existing devices.

17 Apr 2014

Pitt CVR and Sanofi Pasteur join forces to help assess effectiveness of dengue vaccine

The University of Pittsburgh Center for Vaccine Research (CVR) and Sanofi Pasteur, the vaccines division of Sanofi, have entered a scientific collaboration to help assess the effectiveness of a dengue vaccine once introduced for immunization programs.

16 Apr 2014

Scientists discover how bacterium Y. pestis overwhelms lungs to cause pneumonic plague

Northwestern Medicine scientists are continuing to unravel the molecular changes that underlie one of the world's deadliest and most infamous respiratory infections.

15 Apr 2014

S. pneumoniae serotypes differ between primary and post-viral disease

Certain capsular serotypes of Streptococcus pneumoniae are particularly likely to cause disease in people who have recently experienced a respiratory viral infection, study findings indicate.

14 Apr 2014

Scientists shed light on runny nose

Scientists at the University of Colorado School of Medicine have shed light on one of the most common of ailments - the runny nose.

11 Apr 2014

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

11 Apr 2014

Findings pave way for potential therapy to combat H1N1 flu virus

Flu epidemics cause up to half a million deaths worldwide each year, and emerging strains continually threaten to spread to humans and cause even deadlier pandemics. A study by McGill University professor Maziar Divangahi published by Cell Press on April 10 in the journal Immunity reveals that a drug that inhibits a molecule called prostaglandin E2 (PGE2) increases survival rates in mice infected with a lethal dose of the H1N1 flu virus.

11 Apr 2014

Researchers discover mechanism that control normal lung function in patients with BHD syndrome

Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects the lungs, skin and kidneys. Folliculin's absence or mutated state has a cascading effect that leads to deteriorated lung integrity and an impairment of lung function, as reported in their findings in the current issue of Cell Reports.

11 Apr 2014

New drug for treating Rett syndrome is on the horizon

A powerful new drug which could relieve the symptoms of devastating childhood disease Rett syndrome is on the horizon thanks to a funding injection of -180,000.

10 Apr 2014

Forest Laboratories, Almirall receive feedback from FDA regarding fixed dose combination of aclidinium/formoterol

Forest Laboratories, Inc. and Almirall, S.A. today announced that they have recently received feedback from the U.S. Food and Drug Administration (FDA) regarding the fixed dose combination of aclidinium and formoterol.

9 Apr 2014

FDA approves Teva Pharmaceutical's Generic Lovaza Capsules

Teva Pharmaceutical Industries Ltd. announces the approval of the generic equivalent to Lovaza® (Omega-3-Acid Ethyl Esters Capsules, USP), in the United States.

9 Apr 2014

Scientists seek broad, versatile countermeasures effective against several kinds of viruses, other pathogens

A group of University of Washington scientists is seeking broad, versatile countermeasures effective against several different kinds of viruses and other pathogens. The investigators are part of a national push for faster responses to unexpected infectious agents.

9 Apr 2014

Novel study uncovers way coughs and sneezes stay airborne for long distances

The next time you feel a sneeze coming on, raise your elbow to cover up that multiphase turbulent buoyant cloud you're about to expel.

9 Apr 2014

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Janssen Research & Development, LLC ("Janssen") today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA™ (ibrutinib) to the U.S. Food and Drug Administration (FDA) by its collaboration partner Pharmacyclics, Inc.

8 Apr 2014

State highlights: 'Balance billing' protection in N.Y.; L.A. nursing home complaint backlog

Hospital patients in New York are the latest in the nation to gain legal protection against unexpected bills from doctors who won't accept their insurance.

8 Apr 2014

Meda reaches agreement with Valeant to terminate joint ventures

Meda has reached an agreement with Valeant to terminate the companies' joint ventures in Canada, Mexico and Australia in the second quarter of 2014. In all three countries own Meda affiliates have been established.

7 Apr 2014

First Edition: April 7, 2014

Today's headlines include stories about the next round of health law challenges the Obama administration faces as well as the new Medicare Advantage rates scheduled to be announced today.

7 Apr 2014

1/3 of ICU patients develop depression that typically manifests as physical symptoms

A third of intensive care patients develop depression that typically manifests as physical, or somatic, symptoms such as weakness, appetite change, and fatigue, rather than psychological symptoms, according to one of the largest studies to investigate the mental health and functional outcomes of survivors of critical care, published in The Lancet Respiratory Medicine.

7 Apr 2014

A novel device for inhalation drug delivery

Inhalation is an increasingly important route for non-invasive drug delivery for both systemic and local applications. Control of particle size and output plays a critical role in the efficient and effective delivery of oft en expensive medications to the lung.

4 Apr 2014

Respiratory News and Research

Docs who treat patients with severe LAM face agonizing treatment decision

OPKO Health enters into definitive agreement to acquire Inspiro Medical

Pitt CVR and Sanofi Pasteur join forces to help assess effectiveness of dengue vaccine

Scientists discover how bacterium Y. pestis overwhelms lungs to cause pneumonic plague

S. pneumoniae serotypes differ between primary and post-viral disease

Scientists shed light on runny nose

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Findings pave way for potential therapy to combat H1N1 flu virus

Researchers discover mechanism that control normal lung function in patients with BHD syndrome

New drug for treating Rett syndrome is on the horizon

Forest Laboratories, Almirall receive feedback from FDA regarding fixed dose combination of aclidinium/formoterol

FDA approves Teva Pharmaceutical's Generic Lovaza Capsules

Scientists seek broad, versatile countermeasures effective against several kinds of viruses, other pathogens

Novel study uncovers way coughs and sneezes stay airborne for long distances

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

State highlights: 'Balance billing' protection in N.Y.; L.A. nursing home complaint backlog

Meda reaches agreement with Valeant to terminate joint ventures

First Edition: April 7, 2014

1/3 of ICU patients develop depression that typically manifests as physical symptoms

A novel device for inhalation drug delivery

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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