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TSRI scientists describe severe immune overreaction caused by flu infections

Scientists at The Scripps Research Institute have mapped key elements of a severe immune overreaction—a “cytokine storm”—that can both sicken and kill patients who are infected with certain strains of flu virus.

28 Feb 2014

Study: Rising prices is the best way to tackle tobacco-related diseases

A recent study finds that rising prices is, by far, the best way to tackle tobacco-related diseases while ignoring tobacco industry arguments that higher taxes would affect state revenues.

28 Feb 2014

Study: Direct camel-to-human transmission of MERS virus is possible in Saudi Arabia

An estimated three-quarters of camels recently surveyed in Saudi Arabia have evidence of infection with the Middle East Respiratory Syndrome coronavirus (MERS-CoV), the virus responsible for human cases of MERS.

27 Feb 2014

Walgreens at UCSF aims to improve medication use, reduce hospital readmissions

UC San Francisco and Walgreens have opened a unique Walgreens store today on the UCSF campus that aims to improve medication safety, decrease health care costs and help patients use medicines more effectively by offering pharmacist-based patient care and expanded health and wellness services to the community.

27 Feb 2014

Dampening immune response may encourage lung transplant rejection

Organ transplant patients routinely receive drugs that stop their immune systems from attacking newly implanted hearts, livers, kidneys or lungs, which the body sees as foreign.

27 Feb 2014

Prothelia and University of Nevada, Reno enter into agreements with Alexion for development of Laminin-111

Prothelia Incorporated (Prothelia) and University of Nevada, Reno announce that they have entered into strategic agreements with Alexion for the development of Laminin-111, a patented experimental protein replacement therapy for merosin-deficient congenital muscular dystrophy (MDC1A), a life-threatening, ultra-rare disease caused by a genetic deficiency of the Laminin-211 protein.

26 Feb 2014

FDA approves KALYDECO for people with cystic fibrosis

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced the U.S. Food and Drug Administration (FDA) approved a supplemental New Drug Application (sNDA) for KALYDECOTM (ivacaftor) for people with cystic fibrosis (CF) ages 6 and older who have one of eight additional mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. KALYDECO was first approved in January 2012 for people with CF ages 6 and older who have at least one copy of the G551D mutation.

26 Feb 2014

Researchers identify polio-like syndrome in cluster of children from California

Researchers have identified a polio-like syndrome in a cluster of children from California over a one-year period, according to a case report released today that will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.

25 Feb 2014

Isis Pharmaceuticals provides update on ISIS-SMNRx Phase 2 study in infants with SMA

Isis Pharmaceuticals, Inc. today provided an update on its ongoing open label, multiple dose Phase 2 study of ISIS-SMNRx in infants with spinal muscular atrophy (SMA).

25 Feb 2014

Coronavirus responsible for MERS is prevalent in camels throughout Saudi Arabia

The coronavirus responsible for Middle East Respiratory Syndrome (MERS) is prevalent in camels throughout Saudi Arabia and has been around for at least 20 years, according to a study to be published on February 25 in mBio-, the online open-access journal of the American Society for Microbiology.

25 Feb 2014

EarlySense partners with Welch Allyn to increase point of care

EarlySense, the market leader in proactive patient care solutions, together with Welch Allyn, a leading medical diagnostic device company that delivers pragmatic innovation at the point of care, announced today an ongoing strategic partnership.

25 Feb 2014

FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) to update the current label of XELJANZ® (tofacitinib citrate) 5 mg tablets to include radiographic data from two Phase 3 studies, ORAL Scan (A3921044) and ORAL Start.

25 Feb 2014

Humidification of mouth during radiotherapy reduces hospital stay, mucositis in head, neck cancer patients

Patients who received daily humidification of the mouth and throat region beginning from day one of radiation therapy treatment spent nearly 50 percent fewer days in the hospital to manage their side effects, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

CSL Behring enrolls first patient in phase III study of C1-INH for prevention of HAE attacks

CSL Behring today announced it has enrolled the first patient in COMPACT, an international phase III study of a volume-reduced, subcutaneous formulation of C1-esterase inhibitor oncentrate in patients with frequent hereditary angioedema attacks (NCT01912456).

20 Feb 2014

Pharmacyclics total revenue for fourth quarter 2013 increases 113% to $123.6 million

Pharmacyclics, Inc. today reported financial results and recent developments for the quarter and year ended December 31, 2013.

20 Feb 2014

Medicare beneficiaries discharged from nursing homes return to hospital within month

Nursing homes are widely used by Medicare beneficiaries who require rehabilitation after hospital stays. But according to a recent study led by a researcher at the University of North Carolina at Chapel Hill School of Nursing, a high percentage of Medicare patients who are discharged from nursing homes will return to the hospital or the emergency room within 30 days.

20 Feb 2014

Bayer enrolls patients for Phase III trial of Stivarga (regorafenib) tablets in colorectal cancer

Bayer HealthCare today announced that the company has begun to enroll patients in the COAST trial studying Stivarga® (regorafenib) tablets in colorectal cancer (CRC) patients with resected liver metastases.

20 Feb 2014

Research shows that seasonal flu vaccination may reduce risk of stroke

Having the seasonal flu jab could reduce the risk of suffering a stroke by almost a quarter, researchers have found.

20 Feb 2014

Idiopathic pulmonary fibrosis could soon be diagnosed without the need for surgical lung biopsy

People who have suspected idiopathic pulmonary fibrosis without typical patterns on high resolution computed tomography scans could in future be spared the substantial risks of lung biopsy and be given a confident diagnosis of IPF based on clinical and radiological findings alone, according to new research published in The Lancet Respiratory Medicine.

20 Feb 2014

DHS expands business and product offerings with the acquisition of Reliable Home Medical Equipment

Dynamic Healthcare Services, Inc., a portfolio company of GMH Ventures LLC and Lakewood Capital, LLC, announced today that it acquired Reliable Home Medical Equipment, Inc. of Hackensack, NJ on February 10th, 2014. The terms of the acquisition were not disclosed.

20 Feb 2014

Respiratory News and Research

TSRI scientists describe severe immune overreaction caused by flu infections

Study: Rising prices is the best way to tackle tobacco-related diseases

Study: Direct camel-to-human transmission of MERS virus is possible in Saudi Arabia

Walgreens at UCSF aims to improve medication use, reduce hospital readmissions

Dampening immune response may encourage lung transplant rejection

Prothelia and University of Nevada, Reno enter into agreements with Alexion for development of Laminin-111

FDA approves KALYDECO for people with cystic fibrosis

Researchers identify polio-like syndrome in cluster of children from California

Isis Pharmaceuticals provides update on ISIS-SMNRx Phase 2 study in infants with SMA

Coronavirus responsible for MERS is prevalent in camels throughout Saudi Arabia

EarlySense partners with Welch Allyn to increase point of care

FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Humidification of mouth during radiotherapy reduces hospital stay, mucositis in head, neck cancer patients

CSL Behring enrolls first patient in phase III study of C1-INH for prevention of HAE attacks

Pharmacyclics total revenue for fourth quarter 2013 increases 113% to $123.6 million

Medicare beneficiaries discharged from nursing homes return to hospital within month

Bayer enrolls patients for Phase III trial of Stivarga (regorafenib) tablets in colorectal cancer

Research shows that seasonal flu vaccination may reduce risk of stroke

Idiopathic pulmonary fibrosis could soon be diagnosed without the need for surgical lung biopsy

DHS expands business and product offerings with the acquisition of Reliable Home Medical Equipment

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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