Immune System News and Research

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New discoveries made regarding autism onset in mouse models

Although autism is a common neurodevelopmental disorder, the multiple factors behind its onset are still not fully understood.

10 Mar 2023

Montana considers new wave of legislation to loosen vaccination rules

When Deb Horning's youngest daughter was 5, she got her measles, mumps, and rubella shot like many other kindergartners. But unlike many other moms, Horning had to stay away from her daughter for a week after the shot.

10 Mar 2023

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

9 Mar 2023

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Research published today shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver).

9 Mar 2023

Researchers develop a 100%-effective mRNA vaccine for deadly bacteria

For the first time in the world: a team of researchers from Tel Aviv University and the Israel Institute for Biological Research have developed an mRNA-based vaccine that is 100% effective against a type of bacteria that is lethal to humans.

9 Mar 2023

C-reactive protein has a beneficial function in systemic lupus erythematosus

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory disease.

9 Mar 2023

Microglia partner with T cells to cause neurodegeneration, study shows

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

8 Mar 2023

Study suggests a new approach for treating metastatic breast cancers

Metastatic breast cancer has no cure and has proven stubbornly resistant to one of the most innovative and promising new cancer treatments: immunotherapy.

8 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

Study examines the effects of microgravity on human immune system

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

7 Mar 2023

Prevalence and clinical outcomes of viral and bacterial coinfections in hospitalized COVID-19 patients

In a recent study, researchers analyzed the occurrence of bacterial and viral infections in adults hospitalized with coronavirus disease 2019 (COVID-19) to determine the clinical and demographic features, outcomes, and microbial spectrums associated with bacterial coinfections and the prevalence of viral coinfections.

7 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

It may come as a surprise, but bacteria love to grow inside tumors. It's the environment-;tumors are typically acidic, have low amounts of oxygen, and are filled with dead cells, which all facilitate bacterial growth.

6 Mar 2023

'Good autoantibodies' associated with a milder course and lower risk of long Covid

Sometimes in the laboratory there are unexpected results. "Previously it had been observed that autoantibodies are common in severe Covid patients, those who end up in intensive care," says Jonathan Muri, postdoctoral fellow at the Institute for Research in Biomedicine (IRB, affiliated with the Università della Svizzera italiana) and co-author of the study.

6 Mar 2023

How maternal obesity and gestational diabetes can impact DNA methylation in infants

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Immune System News and Research

New discoveries made regarding autism onset in mouse models

Montana considers new wave of legislation to loosen vaccination rules

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Researchers develop a 100%-effective mRNA vaccine for deadly bacteria

C-reactive protein has a beneficial function in systemic lupus erythematosus

Microglia partner with T cells to cause neurodegeneration, study shows

Study suggests a new approach for treating metastatic breast cancers

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

Study examines the effects of microgravity on human immune system

Prevalence and clinical outcomes of viral and bacterial coinfections in hospitalized COVID-19 patients

CDC recommendations and clinical considerations for the treatment of severe Mpox

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

'Good autoantibodies' associated with a milder course and lower risk of long Covid

How maternal obesity and gestational diabetes can impact DNA methylation in infants

Clinical trial shows safety and immunogenicity of temperature-stable experimental TB vaccine

Trial emulation shows the effectiveness of the COVID-19 vaccine in improving long COVID symptoms

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