Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Hormone known to prevent weight gain can help maintain healthy muscles in mice

A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice.

23 Feb 2021

New AI algorithm to fully automate the artificial pancreas system

Diabetes is on the rise worldwide. It is a permanent condition that requires care over a life time. To help manage it, an artificial pancreas system, which automatically measures blood sugar levels to infuse the appropriate amount of insulin into the blood, has now become smarter thanks to AI learning.

23 Feb 2021

COVID-19 and lung cancer have a common pathway, say researchers

A new preprint on the bioRxiv* server describes the common features COVID-19 shares with lung cancer.

19 Feb 2021

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer.

18 Feb 2021

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

Metabolic diseases, such as obesity and type 2 diabetes, have risen to epidemic proportions in the U.S. and occur in about 30 percent of the population. Skeletal muscle plays a prominent role in controlling the body's glucose levels, which is important for the development of metabolic diseases like diabetes.

16 Feb 2021

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and develop prediabetes and hyperinsulemia?

15 Feb 2021

Researchers map the mechanism behind cellular communication

Knowledge on how cells communicate is an important key to understanding many biological systems and diseases.

13 Feb 2021

Novel finding could lead to better treatments for Type 1 and Type 2 diabetes

Monash University researchers have uncovered the barrier to β-cell (beta cell) regeneration that could pave the way for improved treatments for diabetes and diseases that involve organ and tissue damage.

12 Feb 2021

Lifestyle changes in pregnant women linked to epigenetic alterations in babies

A study led by researchers at Lund University in Sweden showed a connection between lifestyle intervention in pregnant women with obesity and epigenetic alterations in the baby. The study is published in the journal Diabetes.

11 Feb 2021

Exercise during pregnancy may help mitigate negative effects of parental obesity in children

New research in mice suggests that exercising during pregnancy may help prevent children- especially boys- from developing health problems related to their parents' obesity. The study is published ahead of print in the Journal of Applied Physiology.

11 Feb 2021

New strategy to optimize the efficacy of neuropeptides for therapeutic applications

Dimerization (Note: combination of two identical or different molecules) of the human neuropeptides oxytocin and vasopressin can produce new types of bioactive molecules.

10 Feb 2021

Scientists present new outlook on latest trends in peptide drug discovery and development

Currently there are more than 80 peptide drugs on the global market and about twice as many in clinical development.

10 Feb 2021

Study identifies new therapeutic targets for treatment of obesity and type 2 diabetes

The GIP receptor in the central nervous system plays a crucial role in the regulation of body weight and food intake.

10 Feb 2021

Immune responses to insulin could help identify individuals at risk for developing type 1 diabetes

Researchers from the Barbara Davis Center for Childhood Diabetes at the University of Colorado Anschutz Medical Campus have found that immune responses to insulin could help identify individuals most at risk for developing Type 1 diabetes.

9 Feb 2021

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of free fatty acids (FFAs). These β cell-derived miR-29s are delivered to the liver, promoting insulin resistance and enhancing hepatic glucose output.

9 Feb 2021

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

A clinical study led by Dr. Jordan Feld, a liver specialist at Toronto Centre for Liver Disease, University Health Network (UHN), showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized.

8 Feb 2021

Vegan diet more effective for boosting weight loss than Mediterranean diet

A vegan diet is more effective for weight loss than a Mediterranean diet, according to a groundbreaking new study that compared the diets head to head.

5 Feb 2021

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

A City of Hope-led research team found that the same gene that increases the risk for Alzheimer's disease, ApoE4, can increase the susceptibility to and severity of COVID-19.

4 Feb 2021

Study finds cancer as the leading cause of death among patients with diabetes

Cancer is the leading cause of death among people with diabetes in England. This is the finding of an 18-year-study of over 300,000 people with diabetes in England, from scientists from Imperial College London and published in the journal The Lancet Diabetes & Endocrinology.

4 Feb 2021

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Aging-US published "Sulforaphane promotes C. elegans longevity and healthspan via DAF- 16/DAF-2 insulin/IGF-1 signaling" which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear.

4 Feb 2021

Insulin News and Research

Further Reading

Hormone known to prevent weight gain can help maintain healthy muscles in mice

New AI algorithm to fully automate the artificial pancreas system

COVID-19 and lung cancer have a common pathway, say researchers

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Researchers map the mechanism behind cellular communication

Novel finding could lead to better treatments for Type 1 and Type 2 diabetes

Lifestyle changes in pregnant women linked to epigenetic alterations in babies

Exercise during pregnancy may help mitigate negative effects of parental obesity in children

New strategy to optimize the efficacy of neuropeptides for therapeutic applications

Scientists present new outlook on latest trends in peptide drug discovery and development

Study identifies new therapeutic targets for treatment of obesity and type 2 diabetes

Immune responses to insulin could help identify individuals at risk for developing type 1 diabetes

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

Vegan diet more effective for boosting weight loss than Mediterranean diet

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

Study finds cancer as the leading cause of death among patients with diabetes

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

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