Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Study: Brain hormones could improve metabolism and fight obesity

A mitochondrial hormone expressed by cells deep in the brain appears to play a role in improving metabolism and fighting off obesity, according to a new study in mice.

3 Feb 2021

New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Researchers have explored heritable factors, age and body mass on temperature variation between humans. One notable finding is that the current threshold for detecting fever in older adults may be too high, precluding the ability to detect COVID-19 early on

2 Feb 2021

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

A new study by researchers in China and the U.S. describes a round-up of the effects of commonly used hypoglycemic drugs on the outcomes of COVID-19 in diabetic patients.

1 Feb 2021

Study: Diabetics worry about disruption to insulin supplies owing to Brexit outcome

Diabetics living in the UK worry about disruption to insulin supplies as a result of Brexit, new research shows.

27 Jan 2021

Study uncovers a novel promising target for diabetes treatment

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum Muenchen, the Technical University of Munich and the German Center for Diabetes Research is a significant milestone for diabetes research as the scientific community celebrates 100 years of insulin and 50 years of insulin receptor discovery.

27 Jan 2021

Hybrid closed-loop insulin therapy improves glycemic control in adolescents, young adults

Hybrid closed-loop insulin therapy improved glycemic control in adolescents and young adults with type 1 diabetes. These outcomes, derived from the International Diabetes Closed-Loop (iDCL) Trial, are reported in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT).

27 Jan 2021

New data shows that mINDY gene is involved in blood pressure regulation

Authors from the German Center for Diabetes Research (DZD) presented data showing that the longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation in the Journal of Clinical Investigation (JCI) insight.

27 Jan 2021

New compound could lead to a new class of diabetes drugs

Research led by The Ohio State University Wexner Medical Center and College of Medicine identified a new compound that might serve as a basis for developing a new class of drugs for diabetes.

27 Jan 2021

Study shows why children of obese mothers have propensity to develop metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop metabolic disease during their lifetime, as suggested by previous research.

26 Jan 2021

Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in response to high levels of free fatty acids (FFAs).

22 Jan 2021

Researchers discover direct link between placental function and future metabolic disorders

Researchers at the University of Colorado Anschutz Medical Campus have discovered a direct association between placental function in pregnant women and future metabolic disorders in children and adults, a finding that could lead to earlier intervention and diagnosis of disease.

22 Jan 2021

New model explains controversies over saturated fats and heart disease risk

In science, sometimes a new perspective can turn our interpretation of the data upside-down, and necessitate a paradigm shift.

22 Jan 2021

Mitochondrial mutation linked to elevated diabetes risk in Japanese men

A new study of Type 2 diabetes in Japanese populations has uncovered a previously uncharacterized genetic variant that puts male carriers at greater risk for the disease, as well as the mechanism by which it does so.

21 Jan 2021

Researchers simulate tailgating to examine the impact of excessive eating and drinking

The NFL playoffs are underway, and fans are finding ways to simulate tailgating during the COVID-19 pandemic. Football watch parties are synonymous with eating fatty foods and drinking alcohol. Have you ever wondered what all of that eating and drinking does to your body?

21 Jan 2021

Insulin resistance, diabetes and metabolic syndrome contribute to premature coronary events in women

While deaths related to heart disease have declined among older people, studies suggest that death rates among younger patients have remained stagnant or increased slightly.

20 Jan 2021

Effects of low-fat, plant-based diet compared to low-carb, animal-based diet

People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study at the National Institutes of Health.

19 Jan 2021

Green Mediterranean diet reduces non-alcoholic fatty liver disease, show randomized trials

A green Mediterranean (MED) diet reduces intrahepatic fat more than other healthy diets and cuts non-alcoholic fatty liver disease (NAFLD) in half, according to a long-term clinical intervention trial led by Ben-Gurion University of the Negev researchers and a team of international colleagues.

18 Jan 2021

New review supports stricter control of HbA1C levels among children with type 1 diabetes

Diabetes is characterized by elevated levels of sugar or glucose (hyperglycemia) in the blood. This occurs due to the lack of the hormone insulin in type 1 diabetes, and to reduced insulin levels in combination with insulin resistance in type 2 diabetes.

15 Jan 2021

Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes

Use of the diabetes drug metformin -- before a diagnosis of COVID-19 -- is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham.

15 Jan 2021

Insulin News and Research

Further Reading

Study: Brain hormones could improve metabolism and fight obesity

New process separates beneficial glucocorticoids from unwanted side-effects

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

Study: Diabetics worry about disruption to insulin supplies owing to Brexit outcome

Study uncovers a novel promising target for diabetes treatment

Hybrid closed-loop insulin therapy improves glycemic control in adolescents, young adults

New data shows that mINDY gene is involved in blood pressure regulation

New compound could lead to a new class of diabetes drugs

Study shows why children of obese mothers have propensity to develop metabolic diseases

Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

Researchers discover direct link between placental function and future metabolic disorders

New model explains controversies over saturated fats and heart disease risk

Mitochondrial mutation linked to elevated diabetes risk in Japanese men

Researchers simulate tailgating to examine the impact of excessive eating and drinking

Insulin resistance, diabetes and metabolic syndrome contribute to premature coronary events in women

Effects of low-fat, plant-based diet compared to low-carb, animal-based diet

Green Mediterranean diet reduces non-alcoholic fatty liver disease, show randomized trials

New review supports stricter control of HbA1C levels among children with type 1 diabetes

Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes

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