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Guidant conceals defibrillator safety problems from FDA, is charged with criminal violations

Medical device manufacturer Guidant LLC, a wholly-owned subsidiary of Boston Scientific Corporation, was charged today with criminal violations of the Federal Food, Drug, and Cosmetic Act related to safety problems with some of its implantable defibrillators. Guidant LLC formerly did business as Guidant Corporation. The Justice Department filed the criminal information today in connection with an agreement with Guidant to resolve the charges. A formal guilty plea agreement is expected to be filed with the court at a later date.

26 Feb 2010

Misperceptions about risk, symptoms and lethality of lung cancer increase mortality rates for lung cancer

A new analysis published this week in the journal Cancer indicates that misperceptions about risk, symptoms and the lethality of lung cancer may play a role in the disproportionately higher incidence and mortality rates for lung cancer among African Americans.

26 Feb 2010

IARS commits over $1M to anesthesia research to advance the specialty of anesthesiology

The International Anesthesia Research Society announced 10 grant recipients in 2009, committing over $1 million to anesthesia research and other projects that will advance the specialty of anesthesiology. Grant recipients include researchers, clinicians and educators from around the world who have provided outstanding contributions to the anesthesia community.

25 Feb 2010

HealthGrades America’s 50 Best Hospitals for 2010 identified

The HealthGrades America’s 50 Best Hospitals for 2010 were identified in a report issued today by the leading independent healthcare ratings organization. The analysis, which examined objective patient outcomes over three years at all 5,000 of the nation’s nonfederal hospitals, found that the 50 Best Hospitals had mortality rates that were, on average, 27% lower than other hospitals.

25 Feb 2010

Chilean hospital's early use of antiviral treatment and aggressive measures helped reduce H1N1 cases

A Chilean hospital's early use of antiviral treatment in influenza patients and other aggressive measures helped reduce the number of severe H1N1 cases and related deaths. Those are the findings of a new study, now available online (http://www.journals.uchicago.edu/doi/abs/10.1086/650750), published in the March 15, 2010 issue of Clinical Infectious Diseases.

25 Feb 2010

Biochemical link between misery and death discovered

In ongoing work to identify how genes interact with social environments to impact human health, UCLA researchers have discovered what they describe as a biochemical link between misery and death. In addition, they found a specific genetic variation in some individuals that seems to disconnect that link, rendering them more biologically resilient in the face of adversity.

25 Feb 2010

New report identifies enormous global impact of preterm birth and stillbirth

A new report issued today identifies the enormous global impact of preterm birth and stillbirth-and what can be done to decrease it. Globally, an estimated 13 million babies are born preterm each year. Newborn deaths now account for more than 42 percent of mortality in children under the age of five, a rise from 37 percent in the year 2000.

24 Feb 2010

Prochymal achieves response rate of 63% when used as rescue therapy in children suffering from GvHD

Osiris Therapeutics, Inc. today reported that a new study shows Prochymal achieved an overall response rate of 63% when used as a rescue therapy in children suffering from severe treatment resistant graft vs. host disease (GvHD).

24 Feb 2010

Phase III trial results of Osiris Therapeutics' Prochymal for GvHD to be presented at BMT Tandem Meeting

Osiris Therapeutics, Inc. today announced that results from the Phase III trial evaluating Prochymal for the treatment of steroid-refractory acute graft vs. host disease (GvHD) will be presented by Paul Martin, M.D., of the Fred Hutchinson Cancer Research Center and Paul Szabolcs, M.D., of Duke University Medical Center at the 2010 BMT Tandem Meeting. The meeting is being held February 24-28 in Orlando, Florida.

24 Feb 2010

Different rates of post-traumatic stress disorder in different countries: Study

A study published in the current issue of Psychotherapy and Psychosomatics provides new insights in the different rates of post-traumatic stress disorder that are found in studies performed in different countries.

24 Feb 2010

HealthGrades names Good Samaritan Hospital as One of America’s 50 Best Hospitals in 2010

Good Samaritan Hospital in Los Angeles is named as One of America’s 50 Best Hospitals in 2010 by HealthGrades, Inc., the nation’s leading independent healthcare ratings organization.

24 Feb 2010

Multidisciplinary care teams can also reduce risk of dying in ICUs of hospitals without intensivists

The severe shortage of specially-trained intensivist physicians has hospital intensive care units (ICUs) nationwide struggling to staff units with critical care teams led by intensivists, even though the presence of these specially trained physicians reduces the risk of death for patients in the ICU. A new Penn Medicine report found that replacing intensivist-led teams with multidisciplinary care teams can also reduce the risk of dying in intensive care units. The study appears in the February 22 edition of the Archives of Internal Medicine.

24 Feb 2010

BSD2000 deep hyperthermia combined with chemotherapy improves quality of life in NSCLC patients

BSD Medical Corporation today announced that a study titled “BSD2000 Deep Hyperthermia Combined with Chemotherapy of PT regimen in Patients with Non-small Cell Lung Cancer” has been published in the current issue of The Chinese Journal of Lung Cancer (February 2010;13(2):132–135) by Yang, Zhao, and Wang.

24 Feb 2010

Individuals with higher midlife BMI scores have lower cognitive ability: Study

The adverse affects of being overweight are not limited to physical function but also extend to neurological function, according to research in the latest issue of the Journals of Gerontology Series A: Biological and Medical Sciences (Volume 65A, Number 1).

24 Feb 2010

Research addresses preterm birth, stillbirth health issues, highlights preventive interventions

New research published in BMC Pregnancy and Childbirth notes some of the "serious short- and long-term health issues" associated with preterm births and identifies steps that can be taken to reduce the number of stillbirths and premature births worldwide, United Press International reports.

24 Feb 2010

Study says lower-cost hospitals don't have lower quality care for certain illnesses

A study Monday in the Archives of Internal Medicine found little difference in outcomes between hospitals with longer patient stays and shorter ones, which could make it "possible to lower costs in the U.S. system without hurting patients," Reuters reports.

24 Feb 2010

Nitric oxide may play key role in the pathogenesis of neonatal meningitis

Current research suggests that nitric oxide may play a role in the pathogenesis of neonatal meningitis. The related report by Mittal et al, "Inhibition of inducible nitric oxide controls pathogen load and brain damage by enhancing phagocytosis of Escherichia coli K1 in neonatal meningitis," appears in the March 2010 issue of The American Journal of Pathology.

24 Feb 2010

FDA grants EUA for Longhorn Influenza A/H1N1-09 Prime RRT-PCR Assay in CLIA high complexity laboratories

Longhorn Vaccines & Diagnostics today announced it has been granted Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) for its Longhorn Influenza A/H1N1-09 Prime RRT-PCR Assay™ in CLIA high complexity laboratories. . The Longhorn Influenza A/H1N1-09 Prime RRT-PCR Assay™ is a ready-use assay that requires no mixing prior to use and has been authorized for use on the ABI 7500.

24 Feb 2010

Prevention of preterm birth and stillbirth: Global collaborative efforts needed

A new report identifies the enormous global impact of preterm birth and stillbirth—and what can be done to decrease it. Globally, an estimated 13 million babies are born preterm each year. Newborn deaths now account for more than 42 percent of mortality in children under the age of five, a rise from 37 percent in the year 2000. Additionally, an estimated 3.2 million are stillborn each year, and many of these losses are linked to maternal deaths.

23 Feb 2010

USPSTF mammography recommendations: Avon Foundation for Women survey confirms states denying coverage

A recent Avon Foundation for Women survey confirms what the American College of Radiology and other experts warned would happen: states are using deeply flawed and widely discredited U.S. Preventative Services Task Force mammography recommendations to deny women coverage for mammograms, and many women are foregoing long proven, life-saving mammography care based on the mistaken USPSTF recommendations.

23 Feb 2010

Mortality News and Research

Guidant conceals defibrillator safety problems from FDA, is charged with criminal violations

Misperceptions about risk, symptoms and lethality of lung cancer increase mortality rates for lung cancer

IARS commits over $1M to anesthesia research to advance the specialty of anesthesiology

HealthGrades America’s 50 Best Hospitals for 2010 identified

Chilean hospital's early use of antiviral treatment and aggressive measures helped reduce H1N1 cases

Biochemical link between misery and death discovered

New report identifies enormous global impact of preterm birth and stillbirth

Prochymal achieves response rate of 63% when used as rescue therapy in children suffering from GvHD

Phase III trial results of Osiris Therapeutics' Prochymal for GvHD to be presented at BMT Tandem Meeting

Different rates of post-traumatic stress disorder in different countries: Study

HealthGrades names Good Samaritan Hospital as One of America’s 50 Best Hospitals in 2010

Multidisciplinary care teams can also reduce risk of dying in ICUs of hospitals without intensivists

BSD2000 deep hyperthermia combined with chemotherapy improves quality of life in NSCLC patients

Individuals with higher midlife BMI scores have lower cognitive ability: Study

Research addresses preterm birth, stillbirth health issues, highlights preventive interventions

Study says lower-cost hospitals don't have lower quality care for certain illnesses

Nitric oxide may play key role in the pathogenesis of neonatal meningitis

FDA grants EUA for Longhorn Influenza A/H1N1-09 Prime RRT-PCR Assay in CLIA high complexity laboratories

Prevention of preterm birth and stillbirth: Global collaborative efforts needed

USPSTF mammography recommendations: Avon Foundation for Women survey confirms states denying coverage

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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