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Slightly to moderately elevated CRP levels in patients undergoing CABG surgery: Implications

A new study published in the March issue of Anesthesiology raises awareness for an additional risk category for patients undergoing routine coronary artery bypass surgery - low to moderate levels of inflammation.

23 Feb 2010

Multidisciplinary rounds may facilitate implementation of best clinical practices: Study

Multidisciplinary care teams consisting of clinicians, nurses and other health care professionals appear to be associated with a lower risk of death among patients in the intensive care unit, according to a report in the February 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. A second report finds that an increasing number of surgical patients are being managed jointly by a surgeon and another clinician, such as a hospitalist or internal medicine sub-specialist.

23 Feb 2010

FDA issues approval for Gileads's Cayston for respiratory symptoms in cystic fibrosis

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Cayston® (aztreonam for inhalation solution) as a treatment to improve respiratory symptoms in cystic fibrosis patients with Pseudomonas aeruginosa. Cayston’s safety and efficacy have not been established in pediatric patients below the age of 7, patients with forced expiratory volume in one second of less than 25 percent or greater than 75 percent predicted, or patients colonized with Burkholderia cepacia.

23 Feb 2010

Study to restrict hemoglobin-based oxygen carriers

study published in the March 2010 issue of the journal Anesthesiology gives researchers new insights in how to better understand and control a severe side effect of hemoglobin-based oxygen carriers (HBOCs), often referred to as "artificial blood."

23 Feb 2010

Multidisciplinary, team-based approach can reduce mortality rates in ICUs

The severe shortage of specially-trained intensivist physicians has hospital intensive care units (ICUs) nationwide struggling to staff units with critical care teams led by intensivists, even though the presence of these specially trained physicians reduces the risk of death for patients in the ICU.

23 Feb 2010

Also in global health news: Infant, maternal mortality in N. Korea; malaria in Cambodia; Zambia PEPFAR program; Pakistan's anti-polio campaign; U.N. Ambassador responds to Somalia; Myanmar refugees

Higher rates of infant and maternal mortality have lead to a decline of life expectancy in North Korea over the past 15 years, census figures, which were obtained with help form the U.N. Population Fund, said on Monday, Agence France-Presse reports (2/22).

23 Feb 2010

Global report identifies causes leading to preterm births and stillbirths

More research and attention are urgently needed to understand and reduce the incidence of preterm births and stillbirths worldwide, according to experts from the Global Alliance to Prevent Prematurity and Stillbirth (GAPPS).

23 Feb 2010

Hospital-acquired infections increase mortality rate and healthcare costs

Two common conditions caused by hospital-acquired infections (HAIs) killed 48,000 people and ramped up health care costs by $8.1 billion in 2006 alone, according to a study released today in the Archives of Internal Medicine.

23 Feb 2010

Black women are more prone to peripartum cardiomyopathy around childbirth time

A study examining the incidence of peripartum cardiomyopathy in women who gave birth at a Medical College of Georgia's teaching hospital between July 2003 and July 2008, showed that while 55 percent of the women were white, 93 percent of those who developed cardiomyopathy were black, said Dr. Mindy B. Gentry, an MCG cardiologist.

23 Feb 2010

Combination of MRI and mammography reduces mortality rate in high-risk women

Annual breast cancer screening with both mammography and magnetic resonance imaging (MRI) is likely to be a cost-effective way to improve life expectancy in women with an increased risk of breast cancer, according to a new study published in the March issue of Radiology.

23 Feb 2010

Acute stroke care and clinical outcomes improve substantially with stroke program

Acute stroke care and clinical outcomes have improved significantly at hospitals participating in the American Heart Association/American Stroke Association's Get With The Guidelines-Stroke program, according to a large study in Circulation: Cardiovascular Quality and Outcomes, a journal of the American Heart Association.

23 Feb 2010

UCI researchers create new breed of flightless mosquitoes for dengue control

UCI researchers and colleagues from Oxitec Ltd. and the University of Oxford created the new breed. Flightless females are expected to die quickly in the wild, curtailing the number of mosquitoes and reducing - or even eliminating - dengue transmission. Males of the strain can fly but do not bite or convey disease.

23 Feb 2010

Study shows hospitals costs vary widely and are not associated with quality of care

The costs that hospitals incur in treating patients vary widely and do not appear to be strongly associated either with the quality of care patients receive or their risk of dying within 30 days, according to a report in the February 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

23 Feb 2010

Alnylam Pharmaceuticals initiates ALN-RSV01 Phase IIb trial in adult lung transplant patients for RSV infection

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated a Phase IIb trial in adult lung transplant patients with ALN-RSV01, an RNAi therapeutic for the treatment of respiratory syncytial virus (RSV) infection. RSV infection in lung transplant patients represents an important unmet medical need; the condition is associated with significant morbidity, including the development of acute lung transplant rejection in 10% to 20% of infected patients.

22 Feb 2010

RNCRR uses Parascript' AccuDetect CAD software to detect breast cancer

Parascript, LLC, the image analysis and pattern recognition solution provider, today announced the use of its AccuDetect computer aided detection (CAD) software by the Russian Center for Roentgeno - Radiology Research in Moscow. RNCRR is Russia's largest, most recognized breast cancer oncology center.

22 Feb 2010

Racial disparities in beliefs about lung cancer

A new survey has found that African-Americans are more likely than whites to hold mistaken and fatalistic beliefs about lung cancer, as well as being more reluctant to consult a doctor about possible symptoms of the disease, according to researchers from Dana-Farber Cancer Institute and their collaborators.

22 Feb 2010

Study comparing open and laparoscopic radical prostatectomy reveals few differences in outcomes

Of the 200,000 men newly diagnosed with prostate cancer each year in the United States, about one-third will undergo surgical treatment. Although open radical prostatectomy (ORP) is regarded as the standard treatment, laparoscopic radical prostatectomy (LRP) with or without robotic assistance is becoming more common.

22 Feb 2010

Health worker training program cuts stillbirths by 30% in 6 developing countries, study says

The rate of stillbirths was cut by more than 30 percent after health workers in rural parts of six developing countries were trained "in how to help a newborn start breathing and to keep it warm and clean," according to a study published in the New England Journal of Medicine, Reuters reports. The trainees - who included midwives, nurses, traditional birth attendants and physicians - were given "hand-held pumps and masks to fill babies' lungs with air if they were not breathing at birth, clean-delivery kits to prevent infection and scales to measure their weight," the news service writes.

20 Feb 2010

Emory School of Medicine to enroll nearly 1,140 people for Phase III clinical trial of progesterone for TBI

Researchers at 17 medical centers across the country soon will begin using the hormone progesterone to treat patients who experience traumatic brain injury (TBI). The treatment is part of a randomized, double-blind Phase III clinical trial that will enroll approximately 1,140 people over a three- to six-year period beginning in March, 2010. The trial is funded by a grant to Emory University from the National Institutes of Health.

20 Feb 2010

Conference for Young Women Affected by Breast Cancer: 10th anniversary

2010 marks the 10th anniversary of the only international conference dedicated to the critical issues of young breast cancer survivors and those who care about them. Nearly 1,000 young breast cancer survivors, caregivers and medical professionals from around the world are expected to attend the 10th Annual Conference for Young Women Affected by Breast Cancer, to be held Friday, Feb. 26-Sunday, Feb. 28 at the Sheraton Atlanta Hotel in Atlanta, Ga.

19 Feb 2010

Mortality News and Research

Slightly to moderately elevated CRP levels in patients undergoing CABG surgery: Implications

Multidisciplinary rounds may facilitate implementation of best clinical practices: Study

FDA issues approval for Gileads's Cayston for respiratory symptoms in cystic fibrosis

Study to restrict hemoglobin-based oxygen carriers

Multidisciplinary, team-based approach can reduce mortality rates in ICUs

Also in global health news: Infant, maternal mortality in N. Korea; malaria in Cambodia; Zambia PEPFAR program; Pakistan's anti-polio campaign; U.N. Ambassador responds to Somalia; Myanmar refugees

Global report identifies causes leading to preterm births and stillbirths

Hospital-acquired infections increase mortality rate and healthcare costs

Black women are more prone to peripartum cardiomyopathy around childbirth time

Combination of MRI and mammography reduces mortality rate in high-risk women

Acute stroke care and clinical outcomes improve substantially with stroke program

UCI researchers create new breed of flightless mosquitoes for dengue control

Study shows hospitals costs vary widely and are not associated with quality of care

Alnylam Pharmaceuticals initiates ALN-RSV01 Phase IIb trial in adult lung transplant patients for RSV infection

RNCRR uses Parascript' AccuDetect CAD software to detect breast cancer

Racial disparities in beliefs about lung cancer

Study comparing open and laparoscopic radical prostatectomy reveals few differences in outcomes

Health worker training program cuts stillbirths by 30% in 6 developing countries, study says

Emory School of Medicine to enroll nearly 1,140 people for Phase III clinical trial of progesterone for TBI

Conference for Young Women Affected by Breast Cancer: 10th anniversary

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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