Respiratory News and Research

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Twice-daily KALYDECO improves lung function in people with cystic fibrosis

Vertex Pharmaceuticals (Australia) Pty Ltd., announces the presentation of data from KALYDECO (ivacaftor) studies at the 10th Australasian Cystic Fibrosis Conference in Auckland, New Zealand, August 17 – 20, 2013, which further demonstrate the benefits of the medicine in people with cystic fibrosis ages 6 and older who have at least one copy of the G551D mutation in the cystic fibrosis transmembrane conductance regulator gene.

21 Aug 2013

More patients suffer from complications after cancer surgery, but only few die

While more patients in the U.S. are suffering from complications such as blood clots and infections after major cancer surgery, fewer are dying from their operations.

20 Aug 2013

Researchers outline recommendations to lower costs and lead to better care for patients

Medical organizations are participating in a campaign to help clinicians and patients avoid wasteful and sometimes harmful medical interventions. Recently, experts in pediatric and adult health from diverse geographic locations of the United States and from a mix of academic and non- academic settings shared their experiences, consulted their colleagues, and analyzed numerous studies in the medical literature to determine the top recommendations for improving healthcare value.

20 Aug 2013

FDA grants Orphan Drug Designation to Alnylam ALN-AT3 for treatment of hemophilia B

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that the U.S. Food & Drug Administration (FDA) has granted an Orphan Drug Designation to ALN-AT3 as a therapeutic for the treatment of hemophilia B.

17 Aug 2013

Investigators link acute viral infections to development of COPD

Investigators at Washington University School of Medicine in St. Louis have described another link in the chain of events that connect acute viral infections to the development of chronic obstructive pulmonary disease (COPD).

16 Aug 2013

Current non-invasive techniques less effective in reducing incidence of lung injury in very premature infants

A neonatologist at The Children's Hospital of Philadelphia is the senior author of a large new study that found that current non-invasive techniques for respiratory support are less effective than widely assumed, in reducing the incidence of severe lung injury in very premature infants.

16 Aug 2013

New findings reveal that older prisoners have unmet health and social care needs

Prisons and partner organizations must do more to provide health and social care to growing population of older prisoners.

From The University of Manchester 14 Aug 2013

Multiple sclerosis patients see "rapid expansion" of effective new treatment options

After decades of research, multiple sclerosis patients are seeing a "rapid expansion" of effective new treatment options, according to a review article in the journal Neurologic Clinics.

14 Aug 2013

Scientists provide insight into emergence of inter-species transmittable viruses

Outbreaks such as the severe acute respiratory syndrome (SARS) Middle East respiratory syndrome coronavirus (MERS) have afflicted people around the world, yet many people think these trends are on the decline.

13 Aug 2013

Perrigo Company and Teva Pharmaceutical launch generic equivalent to temozolomide

Teva Pharmaceutical Industries Ltd. and Perrigo Company today announced the launch of the generic equivalent to Temodar (temozolomide).

13 Aug 2013

Researchers find antibodies specific to MERS-CoV in dromedary camels

Researchers searching for signs of Middle East respiratory syndrome coronavirus in livestock animals have found antibodies specific to the new virus in dromedary camels. The research, published in The Lancet Infectious Diseases, suggests that these animals have encountered MERS-CoV, or a closely related virus, and may be one reservoir of the virus that is causing MERS in humans.

9 Aug 2013

Researchers have made breakthrough changes in design of infant’s inhalation masks

Researchers at the Technion-Israel Institute of Technology have made a breakthrough that could lead to radical changes in the design and effectiveness of inhalation masks for infants.

7 Aug 2013

Virginia Tech addiction expert receives $3.2 million grant to help smokers quit cigarettes

Warren Bickel, an internationally recognized addiction expert at the Virginia Tech Carilion Research Institute, recently received a $3.2-million grant from the National Institute on Drug Abuse for research on improving self-control in smokers seeking to quit cigarettes. The grant will provide Bickel's team with $573,000 to $716,000 a year over five years to develop innovative new ways to enhance the smokers' ability to abstain from acting on their nicotine cravings.

6 Aug 2013

Pediatric trauma patients with preexisting chronic conditions have higher mortality risk

In a recent study published in the Journal of Trauma and Acute Care Surgery, researchers from the Center for Injury Research and Policy in The Research Institute at Nationwide Children's Hospital found that pediatric trauma patients with preexisting chronic conditions have longer hospital stays, higher hospital charges and an increased mortality risk.

6 Aug 2013

New effort could dramatically improve surgical outcomes in children, say surgeons

A group of pediatric surgeons at hospitals around the country have designed a system to collect and analyze data on surgical outcomes in children - the National Surgical Quality Improvement Program (NSQIP) is the first national database able to reliably compare outcomes among different hospitals where children's surgery is performed.

6 Aug 2013

NanoViricides, LRRI sign NDA for IND-enabling efficacy studies on FluCide drug candidates

NanoViricides, Inc. said it has signed a non-disclosure agreement with the Lovelace Respiratory Research Institute. The Company intends to enter into a Master Services Agreement with LRRI for the IND-enabling efficacy studies of both its broad-spectrum injectable and oral FluCide drug candidates.

5 Aug 2013

Research roundup: Making sense (or not) of health insurance; what a full Medicaid expansion could look like; recession and coverage

Each week, KHN reporter Alvin Tran compiles a selection of recently released health policy studies and briefs.

3 Aug 2013

Burning incense generates indoor air pollutants that may cause inflammation in human lung cells

Burning incense, a popular cultural practice in Arabian Gulf countries and elsewhere, generates indoor air pollutants that may cause inflammation in human lung cells, say researchers in the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill.

3 Aug 2013

Physicians prescribe strongest antibiotics capable of killing multiple kinds of bacteria

When U.S. physicians prescribe antibiotics, more than 60 percent of the time they choose some of the strongest types of antibiotics, referred to as "broad spectrum," which are capable of killing multiple kinds of bacteria, University of Utah researchers show in a new study.

2 Aug 2013

Longer looks: mayo's demands; 140 character death watch; posting hospital prices

Every week reporter Ankita Rao selects interesting reading from around the Web.

2 Aug 2013

Respiratory News and Research

Twice-daily KALYDECO improves lung function in people with cystic fibrosis

More patients suffer from complications after cancer surgery, but only few die

Researchers outline recommendations to lower costs and lead to better care for patients

FDA grants Orphan Drug Designation to Alnylam ALN-AT3 for treatment of hemophilia B

Investigators link acute viral infections to development of COPD

Current non-invasive techniques less effective in reducing incidence of lung injury in very premature infants

New findings reveal that older prisoners have unmet health and social care needs

Multiple sclerosis patients see "rapid expansion" of effective new treatment options

Scientists provide insight into emergence of inter-species transmittable viruses

Perrigo Company and Teva Pharmaceutical launch generic equivalent to temozolomide

Researchers find antibodies specific to MERS-CoV in dromedary camels

Researchers have made breakthrough changes in design of infant’s inhalation masks

Virginia Tech addiction expert receives $3.2 million grant to help smokers quit cigarettes

Pediatric trauma patients with preexisting chronic conditions have higher mortality risk

New effort could dramatically improve surgical outcomes in children, say surgeons

NanoViricides, LRRI sign NDA for IND-enabling efficacy studies on FluCide drug candidates

Research roundup: Making sense (or not) of health insurance; what a full Medicaid expansion could look like; recession and coverage

Burning incense generates indoor air pollutants that may cause inflammation in human lung cells

Physicians prescribe strongest antibiotics capable of killing multiple kinds of bacteria

Longer looks: mayo's demands; 140 character death watch; posting hospital prices

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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