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Scientists uncover new way to starve tumor cells to death

For decades, scientists have tried to halt cancer by blocking nutrients from reaching tumor cells, in essence starving tumor cells of the fuel needed to grow and proliferate. Such attempts often have disappointed because cancer cells are nimble, relying on numerous backup routes to continue growing.

24 Jan 2017

New drugs that target neighbour proteins may help halt cancer progression

Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. A complex, interacting network of proteins controls all of a cell's processes, from metabolism to growth and division.

24 Jan 2017

Tulane researchers discover cancer-causing role of protein thought to be tumor suppressor

Tulane University researchers have discovered that the protein PHLDB3, thought to be a potential tumor suppressor, actually allows cancer cells to thrive in pancreatic, prostate, colon, breast, lung, and other common cancers.

24 Jan 2017

New biomarker helps better predict survival after surgical removal of colorectal metastases

Liver metastases are formed from cancer cells that have originated in other organs and migrated to the liver via the bloodstream. Colorectal cancer (cancer of the colon/rectum) can be successfully treated by surgical resection of the metastases in combination with chemotherapy.

23 Jan 2017

Overall survival of advanced NSCLC patients receiving treatment better than untreated patients

Non-small cell lung cancer patients with advanced disease receiving standard of care treatment have a higher overall survival than similar patients not receiving treatment.

19 Jan 2017

‘Collateral lethality’ may create new therapeutic options for several cancers

Cancer cells often delete genes that normally suppress tumor formation. These deletions also may extend to neighboring genes, an event known as "collateral lethality," which may create new options for development of therapies for several cancers.

19 Jan 2017

Chronic kidney disease patients have high out-of-pocket healthcare expenditures, study finds

Patients who have chronic kidney disease but are not on dialysis have higher out-of-pocket healthcare expenses than even stroke and cancer patients, according to a study by researchers at Loyola University Chicago and Loyola Medicine.

18 Jan 2017

Prolonged exposure to work-related stress linked to increased risk of cancers

For men, prolonged exposure to work-related stress has been linked to an increased likelihood of lung, colon, rectal, and stomach cancer and non-Hodgkin lymphoma

17 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

MUSC scientists design novel antibody-based therapy to fight against cancer

Scientists at the Medical University of South Carolina (MUSC) have designed an antibody-based therapy that could target the functions of TGF-beta that cause cancer

12 Jan 2017

Study reveals importance of glutamine metabolism for colon cancer

The importance of glutamine was made clear as a colon cancer specific metabolism. It is known that glutamine metabolism is important for pancreatic cancer, but the importance of glutamine metabolism for colon cancer has been unclear.

10 Jan 2017

NCCN publishes new easy-to-understand patient education resources focused on brain cancer

The National Comprehensive Cancer Network has published the NCCN Guidelines for Patients and NCCN Quick Guide sheets for Brain Cancer - Gliomas—the first in a series of patient education resources focused on Brain Cancer.

10 Jan 2017

SLU expert suggests viewing exercise as daily contribution that offers cumulative health benefits

Have you already faltered on your New Year's resolution to exercise regularly in 2017? Joined a gym, but only worked out two days so far? New workout gear still neatly folded with tags attached? Don't give up your admirable ambition just yet. Instead, consider a new attitude to refocus your approach toward your exercise goal.

10 Jan 2017

Delayed chemotherapy after surgery may benefit lung cancer patients, new Yale study suggests

A new Yale study suggests that patients with a common form of lung cancer may still benefit from delayed chemotherapy started up to four months after surgery, according to the researchers.

6 Jan 2017

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers have developed the first sensor capable of objectively identifying inflammatory bowel disease (IBD) and distinguishing between its two subtypes.

4 Jan 2017

Scientists reveal chemical process behind anti-cancer properties of spicy pepper plant

UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of years.

4 Jan 2017

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

3 Jan 2017

Colon News and Research

Scientists uncover new way to starve tumor cells to death

New drugs that target neighbour proteins may help halt cancer progression

Tulane researchers discover cancer-causing role of protein thought to be tumor suppressor

New biomarker helps better predict survival after surgical removal of colorectal metastases

Overall survival of advanced NSCLC patients receiving treatment better than untreated patients

‘Collateral lethality’ may create new therapeutic options for several cancers

Chronic kidney disease patients have high out-of-pocket healthcare expenditures, study finds

Prolonged exposure to work-related stress linked to increased risk of cancers

Epigenetic changes drive successful metastases of pancreatic cancer cells

MUSC scientists design novel antibody-based therapy to fight against cancer

Study reveals importance of glutamine metabolism for colon cancer

NCCN publishes new easy-to-understand patient education resources focused on brain cancer

SLU expert suggests viewing exercise as daily contribution that offers cumulative health benefits

Delayed chemotherapy after surgery may benefit lung cancer patients, new Yale study suggests

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Scientists reveal chemical process behind anti-cancer properties of spicy pepper plant

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

Nanodiscs deliver customized therapeutic vaccine for treatment of colon, melanoma cancers

Study reveals impact of histology on SBRT treatment in early-stage NSCLC patients

New research offers valuable insight for developing more effective drugs to treat IBD

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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