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State roundup: Nearly 13,000 Calif. hospital workers set to strike

Respiratory therapists, nursing aides, surgical technicians and other patient care workers plan to stage a walkout starting Tuesday morning at five University of California medical centers. More than 12,000 workers from the American Federation of State, County and Municipal Employees are expected to participate in the two-day strike over staffing, pay and pension reform, union officials said. An additional 3,400 workers from the University Professional and Technical Employees union plan a one-day sympathy strike (Gorman, 5/21).

22 May 2013

Naloxegol meets primary and secondary endpoints in two pivotal Phase III studies

AstraZeneca today presented the results of two pivotal Phase III studies of naloxegol showing the 25 mg dose of the investigational drug met its primary and secondary endpoints for efficacy and showed a safety profile consistent with previous studies.

22 May 2013

Boehringer Ingelheim's tiotropium shows promising results in patients with severe persistent asthma

Boehringer Ingelheim today announced data from Phase 2 and Phase 3 studies from the Company's ongoing clinical trial program investigating the efficacy and safety of tiotropium in asthma. These data were presented at the American Thoracic Society International Conference in Philadelphia, Pennsylvania.

22 May 2013

COPD patients also experience significant amounts of chronic pain, researchers say

Chronic obstructive pulmonary disease is primarily associated with the respiratory symptoms that are its hallmark, but in fact, patients who struggle with the disease also experience significant amounts of chronic pain.

22 May 2013

Physical activity: An independent predictor of COPD patients' hospitalizations

Clinical measurement of physical activity appears to be an independent predictor of whether or not patients with chronic obstructive pulmonary disease will end up being hospitalized, according to a new study conducted by researchers in Connecticut.

22 May 2013

Study: Extended azithromycin therapy may offer significant benefits to COPD patients

Extended use of a common antibiotic may prolong the time between hospitalizations for patients suffering from chronic obstructive pulmonary disease, according to a post-hoc analysis of a multicenter study which compared the hospitalization rates of patients treated with a 12-month course of azithromycin to the rates of those treated with placebo.

22 May 2013

Early-life exposure to traffic-related air pollution associated with higher hyperactivity

Early-life exposure to traffic-related air pollution was significantly associated with higher hyperactivity scores at age 7, according to new research from the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center.

21 May 2013

Exposure to air pollution during prenatal period is associated with increased risk of respiratory infection in children

Living near a major roadway during the prenatal period is associated with an increased risk of respiratory infection developing in children by the age of 3, according to a new study from researchers in Boston.

21 May 2013

COPD patients are more oliley to suffre from depression

Patients suffering from chronic obstructive pulmonary disease (COPD) typically suffer from depression more frequently than those without COPD, resulting in higher levels of disability and illness and increasing the overall healthcare burden for the COPD population.

21 May 2013

OSA patients have greater risk of mortality, say researchers

Many studies have shown that men and women who suffer from obstructive sleep apnea (OSA) - a disorder that causes breathing to halt intermittently during sleep - have a higher mortality rate than those who do not have the disorder.

21 May 2013

Grifols signs worldwide licensing agreement for Aradigm's Pulmaquin

Grifols, S.A. and Aradigm Corporation today announced the signing of an exclusive, worldwide license for Aradigm's proprietary formulations of inhaled ciprofloxacin (Pulmaquin and Lipoquin) for the treatment of severe respiratory diseases, including non-cystic fibrosis bronchiectasis.

21 May 2013

First Edition: May 21, 2013

Today's headlines include stories examining how the approaching implementation of some health law provisions is highlighting key policy questions.

21 May 2013

U-M-led researchers examine factors that contribute to resurgence of pertussis

Whooping cough has exploded in the United States and some other developed countries in recent decades, and many experts suspect ineffective childhood vaccines for the alarming resurgence.

21 May 2013

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

New research suggests that for some hospitalized ICU patients on mechanical ventilators, using headphones to listen to their favorite types of music could lower anxiety and reduce their need for sedative medications.

21 May 2013

Exercise-induced bronchoconstriction (EIB) guidelines: an interview with Dr Jonathan Parsons, The Ohio State University Asthma Center

Exercise-induced bronchospasm (EIB) is defined as acute, transient airway narrowing that occurs in association with exercise. Exercise-induced bronchospasm can occur during or, more frequently, after exercise.

21 May 2013

Childhood respiratory infections rather than analgesics usage linked to risk for asthma

A new study conducted by Boston researchers reports that the link between asthma and early childhood use of acetaminophen or ibuprofen may be driven by underlying respiratory infections that prompt the use of these analgesics, rather than the drugs themselves.

21 May 2013

Researchers identify novel biomarkers for predicting mortality in ICU patients

A metabolic profile of intensive care unit patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

21 May 2013

Lung Volume Reduction Coil may play key role in treatment of emphysema, study finds

A small, easily implantable device called the Lung Volume Reduction Coil may play a key role in the treatment of two types of emphysema, according to a study conducted in Europe. Results of the study indicate the beneficial effects of the device persist more than a year after initial treatment.

21 May 2013

People exposed to wood and tobacco smoke are at greater risk for developing COPD

People who are consistently exposed to both wood smoke and tobacco smoke are at a greater risk for developing chronic obstructive pulmonary disease and for experiencing more frequent and severe symptoms of the disease, as well as more severe airflow obstruction, than those who are exposed to only one type of smoke, according to the results of a new population-based study conducted by researchers in Colombia.

21 May 2013

Study reports good long-term outcomes after surgery in infants with PFSDH

Posterior fossa subdural hematoma is a serious and rare condition in newborns, generally occurring after difficult deliveries. But with appropriate treatment, there's an excellent chance of good long-term outcomes even in severe cases of PFSDH, reports a study in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

21 May 2013

Respiratory News and Research

State roundup: Nearly 13,000 Calif. hospital workers set to strike

Naloxegol meets primary and secondary endpoints in two pivotal Phase III studies

Boehringer Ingelheim's tiotropium shows promising results in patients with severe persistent asthma

COPD patients also experience significant amounts of chronic pain, researchers say

Physical activity: An independent predictor of COPD patients' hospitalizations

Study: Extended azithromycin therapy may offer significant benefits to COPD patients

Early-life exposure to traffic-related air pollution associated with higher hyperactivity

Exposure to air pollution during prenatal period is associated with increased risk of respiratory infection in children

COPD patients are more oliley to suffre from depression

OSA patients have greater risk of mortality, say researchers

Grifols signs worldwide licensing agreement for Aradigm's Pulmaquin

First Edition: May 21, 2013

U-M-led researchers examine factors that contribute to resurgence of pertussis

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

Exercise-induced bronchoconstriction (EIB) guidelines: an interview with Dr Jonathan Parsons, The Ohio State University Asthma Center

Childhood respiratory infections rather than analgesics usage linked to risk for asthma

Researchers identify novel biomarkers for predicting mortality in ICU patients

Lung Volume Reduction Coil may play key role in treatment of emphysema, study finds

People exposed to wood and tobacco smoke are at greater risk for developing COPD

Study reports good long-term outcomes after surgery in infants with PFSDH

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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