Respiratory News and Research

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Breo Ellipta gets FDA approval for treatment of airflow obstruction in patients with COPD

The U.S. Food and Drug Administration today approved Breo Ellipta (fluticasone furoate and vilanterol inhalation powder) for the long-term, once-daily, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease, including chronic bronchitis and/or emphysema.

13 May 2013

COPD patients with allergic phenotype have increased risk of lower respiratory symptoms, exacerbations

Patients with chronic obstructive pulmonary disease (COPD) who also have allergic disease have higher levels of respiratory symptoms and are at higher risk for COPD exacerbations, according to a new study from researchers at Johns Hopkins University in Baltimore.

10 May 2013

Operating without interrupting warfarin treatment during cardiac device surgery reduces hematomas

A new Canadian study shows that operating without interrupting warfarin treatment at the time of cardiac device surgery is safe and markedly reduces the incidence of clinically significant hematomas compared to the current standard of care.

10 May 2013

ScinoPharm Taiwan, Coland Holdings partner to develop generic oncological drugs for China

ScinoPharm Taiwan Ltd. and Coland Holdings Ltd. announced today that they have formed a strategic alliance to develop a series of generic oncological drugs for Mainland China.

10 May 2013

FDA approves Novartis' Ilaris for treatment of active systemic juvenile idiopathic arthritis

Novartis announced that the US Food and Drug Administration has approved Ilaris (canakinumab) for the treatment of active systemic juvenile idiopathic arthritis in patients aged 2 years and older.

10 May 2013

SDCL researchers to use BioMark equipment to test for infectious diseases

Saskatchewan patients will benefit from faster, more accurate disease identification, thanks to a ground-breaking new technology in infectious disease testing at the Saskatchewan Disease Control Laboratory.

10 May 2013

AACN to present Marguerite Rodgers Kinney Award for a Distinguished Career to MGH's Sally Millar

The American Association of Critical-Care Nurses will present the Marguerite Rodgers Kinney Award for a Distinguished Career to Sally Millar, RN, MBA. She will receive this Visionary Leadership Award for contributions to AACN's mission and vision at the 2013 National Teaching Institute & Critical Care Exposition, Boston, May 18-23.

10 May 2013

New biosensor detects antibiotic resistance in bacteria, can help fight superbugs

On May 8th JoVE will publish research that demonstrates how a biosensor can detect antibiotic resistance in bacteria. This new technology is a preliminary step in identifying and fighting superbugs, a major public health concern that has led to more deaths than AIDS in the United States in recent years.

9 May 2013

Trevena, Forest sign collaborative agreement to develop TRV027 for treatment of ADHF

Trevena, Inc., a clinical stage pharmaceutical company and the leader in the discovery and development of G-protein coupled receptor biased ligands, and Forest Laboratories Holding Limited, a subsidiary of Forest Laboratories Inc., an international pharmaceutical company, announced today that they have entered into a collaborative licensing option agreement for the development of TRV027, an AT1R biased-ligand that recently completed Phase 2a clinical trials.

9 May 2013

FDA accepts Merck's BLA for investigational ragweed pollen sublingual allergy immunotherapy tablet

Merck, known as MSD outside the United States and Canada, today announced that the Biologics License Application for its investigational ragweed pollen (Ambrosia artemisiifolia) sublingual allergy immunotherapy tablet has been accepted for review by the U.S. Food and Drug Administration.

9 May 2013

Walgreens to open new flagship store in San Francisco

Walgreens will officially open the doors to its newest flagship store on Wednesday, May 8.

8 May 2013

Swedish researchers report simple habit to protect against allergy development in children

Allergies are very common in industrialized countries. It has been suggested that exposure to harmless bacteria during infancy may be protective against the development of allergy. However, it has been difficult to pinpoint which bacteria a baby should be exposed to, and at what time and by which route this exposure should ideally occur.

8 May 2013

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung.

7 May 2013

Nationwide movement against early elective deliveries prompts U.S. hospitals to adopt new policies

A national movement to eliminate non-medically indicated (NMI) delivery before 39 weeks has prompted nearly two-thirds of all U.S. hospitals handling non-emergency births to adopt specific policies against the practice, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

7 May 2013

Ultrafine particles in consumer products can cause lung inflammation

A consortium of scientists from across the country has found that breathing ultrafine particles from a large family of materials that increasingly are found in a host of household and commercial products, from sunscreens to the ink in copy machines to super-strong but lightweight sporting equipment, can cause lung inflammation and damage.

7 May 2013

Scientists uncover unknown virulence factor in respiratory pathogen

To infect its host, the respiratory pathogen Pseudomonas aeruginosa takes an ordinary protein usually involved in making other proteins and adds three small molecules to turn it into a key for gaining access to human cells.

7 May 2013

TBI in older adults presents special diagnostic, management and treatment challenges

Each year more than 1.7 million people in the United States sustain a traumatic brain injury (TBI). The incidence of TBI in older adults poses special diagnostic, management and treatment challenges, say experts in a special collection of papers on TBI in the elderly in NeuroRehabilitation: An Interdisciplinary Journal.

7 May 2013

Aeras receives grant to support the development of vaccines against TB, HIV and malaria

Aeras, a nonprofit biotech advancing TB vaccines for the world, the University of Oxford and Okairos, a biopharmaceutical company specializing in T-cell vaccines, today announced a $2.9 million grant to Aeras in support of a collaboration among the three parties to support the development of vaccines against tuberculosis, HIV and malaria.

7 May 2013

Vitamin C may decrease impact of smoking during pregnancy on childhood respiratory health

Pregnant women are advised not to smoke during pregnancy because it can harm the baby's lungs and lead to wheezing and asthma, among other problems. If a woman absolutely can't kick the habit, taking vitamin C during pregnancy may improve her newborn's lung function and prevent wheezing in the first year of life, according to a study to be presented Saturday, May 4, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

4 May 2013

Children admitted in out-of-hours emergencies are at no greater risk of dying

Children admitted to UK intensive care units in out-of-hours emergencies are at no greater risk of dying than children arriving during normal working hours, according to new research.

3 May 2013

Respiratory News and Research

Breo Ellipta gets FDA approval for treatment of airflow obstruction in patients with COPD

COPD patients with allergic phenotype have increased risk of lower respiratory symptoms, exacerbations

Operating without interrupting warfarin treatment during cardiac device surgery reduces hematomas

ScinoPharm Taiwan, Coland Holdings partner to develop generic oncological drugs for China

FDA approves Novartis' Ilaris for treatment of active systemic juvenile idiopathic arthritis

SDCL researchers to use BioMark equipment to test for infectious diseases

AACN to present Marguerite Rodgers Kinney Award for a Distinguished Career to MGH's Sally Millar

New biosensor detects antibiotic resistance in bacteria, can help fight superbugs

Trevena, Forest sign collaborative agreement to develop TRV027 for treatment of ADHF

FDA accepts Merck's BLA for investigational ragweed pollen sublingual allergy immunotherapy tablet

Walgreens to open new flagship store in San Francisco

Swedish researchers report simple habit to protect against allergy development in children

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Nationwide movement against early elective deliveries prompts U.S. hospitals to adopt new policies

Ultrafine particles in consumer products can cause lung inflammation

Scientists uncover unknown virulence factor in respiratory pathogen

TBI in older adults presents special diagnostic, management and treatment challenges

Aeras receives grant to support the development of vaccines against TB, HIV and malaria

Vitamin C may decrease impact of smoking during pregnancy on childhood respiratory health

Children admitted in out-of-hours emergencies are at no greater risk of dying

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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