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Touch of MIDAS to prepare the world for contagious outbreaks

To help the nation-and the world-understand and prepare for contagious outbreaks, the National Institutes of Health's Models of Infectious Disease Agent Study (MIDAS) adds new research expertise to increase its capacity to simulate disease spread, evaluate different intervention strategies and help inform public health officials and policymakers.

4 Sep 2009

World should contribute $23B to increase women's access to contraception, UNFPA says

The United Nations Population Fund (UNFPA) on Tuesday "appealed for the world to contribute more to improve women's health and access to contraception," Agence France-Presse reports.

4 Sep 2009

Insecticide-treated bed nets prevent infant deaths from malaria

Giving insecticide-treated bed nets to nearly 18,000 mothers at prenatal clinics in the Democratic Republic of Congo prevented an estimated 414 infant deaths from malaria, a study by University of North Carolina at Chapel Hill researchers concludes.

3 Sep 2009

New York Times examines efforts to stop spread of dengue in Asia

"While emerging diseases like influenza A(H1N1), also known as swine flu, continue to dominate the headlines, experts say dengue is not only thriving in many endemic areas, it is also spreading to countries previously unaffected by the disease," New York Times writes.

3 Sep 2009

AVA issues guidelines for disinfecting IV catheters

How to meet new infection-control guidelines from the Joint Commission and the SHEA/IDSA Compendium will be the focus of a panel discussion at the upcoming annual meeting of the Association for Vascular Access (AVA).

3 Sep 2009

Death rate from unintentional poisoning triples in middle-aged white women

While the total mortality rate from unintentional injury increased in the U.S. by 11 percent between 1999 and 2005, far larger increases were seen in some subgroups analyzed by age, race, ethnicity and type of injury by researchers at the Johns Hopkins Bloomberg School of Public Health's Center for Injury Research and Policy.

2 Sep 2009

Antibiotic used to treat trachoma reduces child mortality in Ethiopia, study finds

The antibiotic used to treat trachoma, "the world's leading preventable cause of blindness," may also protect children living in Ethiopia from death from of other diseases, according to a recent study, the Associated Press reports.

2 Sep 2009

ICD implantation reduces mortality in heart attack patients

Findings from the latest PreSCD II analysis show that patients protected against sudden cardiac death by an implantable cardioverter defibrillator (ICD) one month or more after MI showed a non-significantRemarkably," says investigator Professor Heinz Völler from the Klinik am See in Ruedersdorf, Germany, "we observed in the data a survival benefit that increased with the time interval between MI and ICD implantation."

2 Sep 2009

Pre-hospitalization strategies will bring down mortality rate of patients with heart disorders

Mortality rate following a heart attack has fallen by more than 50% in Europe over the past 25 years. However, because only minor advances in the medical treatment of AMI are expected over the next decade, it is through organisational changes in the pre-hospital phase that mortality rate will continue this decline to below 5%.

2 Sep 2009

The Kyoto Heart study shows positive effect of valsartan on cardiovascular outcome

The KYOTO HEART Study, which took place in Japan between January 2004 and January 2009, shows that the addition of valsartan to conventional antihypertensive treatment to improve blood pressure control is associated with an improved cardiovascular outcome in Japanese hypertensive patients at high risk of CVD events.

2 Sep 2009

FDA: Randomized clinical trial necessary to better interpret Clolar’s efficacy and safety in adult AML

Genzyme Corporation (Nasdaq: GENZ) announced today that the FDA’s Oncologic Drugs Advisory Committee voted 9 to 3 that a randomized, controlled trial is needed to support the currently proposed label expansion for Clolar® (clofarabine) in adult myeloid leukemia (AML). The committee found that the single-arm clinical study results submitted to support the label expansion showed Clolar was an active agent in acute AML patients, but concluded that a randomized clinical trial should be necessary to better interpret Clolar’s efficacy and safety in the proposed patient population.

2 Sep 2009

MADIT-CRT trial reveals reduced risk of heart failure from CRT-D therapy

Asymptomatic or mildly symptomatic cardiac patients randomised to an implanted cardiac resynchronisation device with defibrillator (CRT-D) have a 34% lower risk of heart failure or death than those receiving a standard implanted cardioverter defibrillator (ICD-only) (HR 0.66,>

2 Sep 2009

Defibrillator-cardiac resynchronization therapy combination reduces heat failure risk

Patients who had a cardiac resynchronization device combined with a defibrillator (CRT-D) implanted had a 34 percent reduction in their risk of death or heart failure when compared to patients receiving only an implanted cardiac defibrillator (ICD), according to a landmark study published online today in the New England Journal of Medicine and presented today at the European Society of Cardiology Congress (ESC) in Barcelona, Spain.

2 Sep 2009

Primary angioplasty procedures vary in European countries

Primary angioplasty (with stent implantation) is the most effective therapy for acute myocardial infarction (AMI), but it is not available to many patients, even though most European countries have sufficient resources (ie, catheterisation laboratories) for its wider use.

2 Sep 2009

PROTECT clinical study aimed at the assessment of rolofylline effects

Despite the promising findings of the PROTECT Pilot study, the larger PROTECT trial found no difference with rolofylline versus placebo with respect of the primary and main secondary end-points of the study. Although more rolofylline patients than placebo patients experienced moderate or marked dyspnea improvement at 24 and 48 hours from randomization, this was counterbalanced by a lack of effect on persistent renal impairment. Lastly, the risk of important neurological events was increased in patients on rolofylline.

2 Sep 2009

Study reveals that valsartan prevents cardiovascular events in high-risk hypertensive Japanese patients

2 Sep 2009

Waist-hip ratio is a better of measure of obesity in older patients

Body mass index (BMI) readings may not be the best gauge of obesity in older adults, according to new research from UCLA endocrinologists and geriatricians. Instead, they say, the ratio of waist size to hip size may be a better indicator when it comes to those over 70.

2 Sep 2009

PLATO study reveals that ticagrelor reduces the rate of cardiovascular events

The presentation of the PLATO (A Study of Platelet Inhibition and Patient Outcomes), showed that ticagrelor (Brilinta) reduced the rate of cardiovascular (CV) events (CV death, myocardial infarction or stroke) from 11.7% to 9.8% compared clopidogrel (Plavix®) XX% (p<0.001, RRR = 16%), without an increase in major bleeding.

2 Sep 2009

Less-invasive, organ-sparing endoscopic therapy for treating early stages of esophageal cancer

Researchers have found that early stage cancers of the esophagus can be treated as effectively by less-invasive, organ-sparing endoscopic therapy as compared to more complex surgical removal of the esophagus, according to a Mayo Clinic study published in the September 2009 issue of Gastroenterology.

2 Sep 2009

Majority of women depend on family or friend's opinion to decide on breast cancer surgery

About three-quarters of women newly diagnosed with breast cancer have a friend or family member with them at their first visit with a surgeon. And that person plays a significant role in the patient's decision of what type of surgery to have, according to a new study from the University of Michigan Comprehensive Cancer Center.

2 Sep 2009

Mortality News and Research

Touch of MIDAS to prepare the world for contagious outbreaks

World should contribute $23B to increase women's access to contraception, UNFPA says

Insecticide-treated bed nets prevent infant deaths from malaria

New York Times examines efforts to stop spread of dengue in Asia

AVA issues guidelines for disinfecting IV catheters

Death rate from unintentional poisoning triples in middle-aged white women

Antibiotic used to treat trachoma reduces child mortality in Ethiopia, study finds

ICD implantation reduces mortality in heart attack patients

Pre-hospitalization strategies will bring down mortality rate of patients with heart disorders

The Kyoto Heart study shows positive effect of valsartan on cardiovascular outcome

FDA: Randomized clinical trial necessary to better interpret Clolar’s efficacy and safety in adult AML

MADIT-CRT trial reveals reduced risk of heart failure from CRT-D therapy

Defibrillator-cardiac resynchronization therapy combination reduces heat failure risk

Primary angioplasty procedures vary in European countries

PROTECT clinical study aimed at the assessment of rolofylline effects

Study reveals that valsartan prevents cardiovascular events in high-risk hypertensive Japanese patients

Waist-hip ratio is a better of measure of obesity in older patients

PLATO study reveals that ticagrelor reduces the rate of cardiovascular events

Less-invasive, organ-sparing endoscopic therapy for treating early stages of esophageal cancer

Majority of women depend on family or friend's opinion to decide on breast cancer surgery

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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