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Genetic innovations for pneumonia diagnosis in children

Polymerase chain reaction could help diagnose Mycoplasmia pneumonia infection in children, researchers say.

24 Dec 2012

Comorbidity could alter joint arthroplasty prognosis

The long-term outcome of hip and knee arthroplasty may be significantly influenced by comorbidity, suggest results from a large register-based study of over 96,000 osteoarthritis patients.

22 Dec 2012

Nurse behavior makes patients feel safe

Hospitalized patients over the age of 65 years feel safe in hospital when their nurses can anticipate and provide attentive care, are predictable and responsive, interact on a personal level, and advocate or intervene on their behalf, indicate study results.

22 Dec 2012

High-dose rifampicin combination could improve meningitis survival

A treatment regimen including high-dose rifampicin administered intravenously in addition to standard or high-dose moxifloxacin has an acceptable safety profile and could improve survival for patients with tuberculous meningitis, indicate phase II trial results.

22 Dec 2012

Molecule imitating a virus may trigger inappropriate immune response

Why would our immune system turn against our own cells? This is the question that the combined Inserm/CNRS/ Pierre and Marie Curie University/Association Institut de Myologie have strived to answer in their "Therapies for diseases of striated muscle", concentrating in particular on the auto-immune disease known as myasthenia gravis.

21 Dec 2012

New technique may prevent inheritance of mitochondrial diseases in children

A joint team of scientists from The New York Stem Cell Foundation (NYSCF) Laboratory and Columbia University Medical Center (CUMC) has developed a technique that may prevent the inheritance of mitochondrial diseases in children.

21 Dec 2012

The war on terror: High rates of stoma creation after colorectal injury

Over one third of military personnel in Iraq and Afghanistan who sustain colorectal injury undergo fecal diversion, show coalition force data.

20 Dec 2012

Slushy spares kidney during partial nephrectomy

US researchers report the success and feasibility of a novel method of carrying out partial nephrectomy in kidney patients, using minimally invasive surgery.

20 Dec 2012

Palliative care consultation may benefit heart failure patients

Symptomatic heart failure patients experience a high prevalence of pain and symptom burden akin to the experiences of cancer patients, say researchers, who report that a palliative care consultation in this population could reduce these factors.

20 Dec 2012

Primary opponensplasty superior to osteosynthesis

Primary opponensplasty in toe transfers provides active restoration of thumb opposition and significantly better restoration of tripod pinch than does static opposition with osteosynthesis , research suggests.

20 Dec 2012

CBT boosts response in medication-resistant depression

Patients with depression who have not responded to pharmacologic treatment should be offered cognitive behavioral therapy, suggest the results of a randomized trial conducted in a primary care setting.

20 Dec 2012

Antibiotic amoxicillin ineffective for treating cough according to European trial

The antibiotic amoxicillin, that doctors typically prescribe for common lower respiratory tract infections (LRTI) such as cough and bronchitis, is no more effective at relieving symptoms than the use of no medication, even in older patients. The findings from the largest randomised placebo controlled trial of antibiotics for acute uncomplicated LRTI to date are published Online First in The Lancet Infectious Diseases.

20 Dec 2012

New clues in understanding how epithelial cells repair themselves following chlorine-related injury

Scarring of the airways can lead to long-term breathing problems for some people exposed to high levels of chlorine gas from events such as an industrial accident, chemical spill following a train derailment or terroristic chemical warfare. Household mishaps from mixing bleach with acidic cleaning products also can cause release of chlorine gas; if this occurs in a poorly ventilated space, chlorine levels could be high enough to cause lung injury.

20 Dec 2012

Lou Gehrig's disease may be treatable using neural stem cells

Promising new research provides evidence that ALS, amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, may be treatable using neural stem cells.

20 Dec 2012

People with chronic shortness of breath may soon have new way to help alleviate their discomfort

People experiencing chronic shortness of breath may soon have a new way to help alleviate their discomfort, according to a Penn State College of Medicine pulmonology researcher.

20 Dec 2012

Personalized rectal cancer therapy shows promise

Personalized chemotherapy for rectal cancer results in high rates of pathologic response, indicate the results of a pilot study.

19 Dec 2012

Kids misuse holiday baking ingredients for drug-like effect

Watch your kitchen cupboards this season as thrillseekers look to common holiday baking ingredients for a rise - cinnamon, nutmeg and even marshmallows are the primary ingredient in trendy risky behavior.

19 Dec 2012

Infectex initiates enrollment in SQ109 Phase IIb-III trial for MDR-TB

Infectex, a Russian biotech company in Maxwell Biotech Venture Fund's portfolio, announced today enrollment of the first patients in its Phase IIb-III clinical trial of SQ109 for MDR-TB. Infectex was founded in 2011 to develop and commercialize innovative products for the treatment of TB.

19 Dec 2012

HAL Allergy completes enrollment in SUBLIVAC FIX Phleum pratense Phase II trial

HAL Allergy B.V. today announced that it has successfully completed patient enrollment in its Phase II trial with SUBLIVAC FIX Phleum pratense.

19 Dec 2012

Jagaricin and antifungal drugs: an interview with Prof Christian Hertweck

Most people have already experienced a fungal infection (mycosis) of the outer layer of the skin, athlete’s foot or ringworm. Whereas such infections may be cumbersome and often difficult to cure, usually they are not dangerous. However, in cases where a fungus causes a systemic infection, this is, it infects internal organs such as lungs or brain, the infection may turn into a life-threatening disease. Of course, only pathogenic fungi cause problems and the degree of virulence varies.

18 Dec 2012