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Hemin as a potential therapy for COVID-19

The current study explores the antiviral activity of HO-1 induced by hemin against SARS-CoV-2 and attempts to describe the mechanism of its anti-viral action.

8 Nov 2021

SARS-CoV-2 Nsp1 deletions affect protein stability and translation inhibition

A new study discusses the purification of various Nsp1 proteins isolated from several mutated variants of SARS-CoV-2.

8 Nov 2021

Rapid antibody response induced by mRNA COVID vaccines in mice

A new study posted in the bioRxiv* preprint server used mouse models to investigate how mRNA vaccines elicit a rapid antibody response. Their findings show two different mRNA vaccines successfully boost antibody levels — IL-5, IL-6, and MCP-1 —5 days after administration.

7 Nov 2021

Convalescent plasma post-vaccination increases binding and neutralizing antibodies against SARS-CoV-2 variants

A recent study assesses the boost in antibodies against SARS-CoV-2)variants post-vaccination in plasma samples from previously infected COVID-19 patients.

7 Nov 2021

Murine hepatitis virus as a surrogate for studying SARS-CoV-2 in food processing biofilms

Researchers from Texas A&M University inoculated MHV (SARS-CoV-2 surrogate) into a meat processing environmental biofilm and developed it on stainless steel (SS), PVC, and tiles at 7°C.

4 Nov 2021

Development of SARS-CoV-2 detection platform using surface-enhanced Raman spectroscopy

Researchers have tried to develop an innovative platform for ultrasensitive and rapid detection of SARS-CoV-2 by exploiting a variation of Raman Spectroscopy.

4 Nov 2021

Identification of novel SARS-CoV-2 alpha variant sub-lineage in Europe

Scientists from Germany have recently identified a new sub-lineage of the alpha variant of SARS-CoV-2 in some European countries.

4 Nov 2021

Cas13 shines a light on SARS-CoV-2 variants

Now, a new study published on the medRxiv* preprint server describes and benchmarks SHINEv2, a Cas13-based nucleic acid diagnostic for SARS-CoV-2 detection. SHINEv2 combines temperature sample processing and lyophilized reagents to simplify the test procedure and assay distribution immensely.

4 Nov 2021

The influence of SARS-CoV-2 vaccination time on antibody response in healthcare workers

In this study, the researchers observed a significant effect of time of vaccination on the vaccine-induced SARS-CoV-2 immunity, which was estimated by measuring the anti-Spike antibody levels.

2 Nov 2021

Humoral and cell-mediated immunity six months post BNT162b2 vaccination

A recent study has evaluated vaccine-induced humoral and cellular immunity against SARS-CoV-2 six months post BNT162b2 (Pfizer-BioNTech) vaccination.

2 Nov 2021

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

A new study aimed to identify several potent neutralizing RBD-directed and NTD-directed mAbs that used a nanoparticle displaying the S glycoprotein to capture SARS-CoV-2-specific B cells.

2 Nov 2021

SARS-CoV-2 variants neutralized by camel nanobodies

Researchers from the US recently isolated two VHH nanobodies - 7A3 and 8A2 - from dromedary camels (Camelus dromedaries) using phage display. These nanobodies were found to have a high affinity for the spike RBD and broad neutralization abilities against SARS-CoV-2 and its variants.

2 Nov 2021

SARS-CoV-2 antibodies persisting for nearly a year, including to delta: NZ study

A cohort study found that antibodies to the SARS-CoV-2 spike protein and neutralizing antibodies remain relatively stable 8-11 months post-infection.

1 Nov 2021

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

The researchers investigated the neutralizing activity of turmeric root extract, curcumin-containing capsules, and pure curcumin against SARS-CoV-2.

1 Nov 2021

The Connection between High-sensitivity Troponin and Heart Attacks

This interview outlines the connection between high-sensitivity troponin and heart attacks.

From Siemens Healthineers 1 Nov 2021

Clinical assay validation for SARS-CoV-2 sequencing using Swift Biosciences amplicon panel

The current study used the guidelines of the FDA to validate the one-tube SARS-CoV-2 Swift Normalase Amplicon Panel Version 2.0 from Swift Biosciences.

31 Oct 2021

New Canadian serology solution for SARS-CoV-2 infections and vaccination

A new study developed a “Made-in-Canada” solution for enabling scalable and reproducible SARS-CoV-2 serology.

31 Oct 2021

Breakthrough COVID infections in Northeast Italy showing waning vaccine protection

Researchers analyze an outbreak of breakthrough infections in a small nursing home in Northerneastern Italy.

28 Oct 2021

Panel of broadly neutralizing SARS-CoV-2 nanobodies for immune assay application

In this study, a team of researchers from Japanese institutions provide a panel of broadly neutralizing nanobodies that detect four VOCs.

28 Oct 2021

N antibodies following SARS-CoV-2 Alpha and Delta infections by vaccination status

A new study, published on the medRxiv* preprint server, has focused on the use of anti-nucleocapsid (N) antibody positivity as a marker of SARS-CoV-2 infection. In the present study, these antibody markers were evaluated using serological surveillance studies post-vaccination amidst circulation of variants of concern.

28 Oct 2021

Assay News and Research

Hemin as a potential therapy for COVID-19

SARS-CoV-2 Nsp1 deletions affect protein stability and translation inhibition

Rapid antibody response induced by mRNA COVID vaccines in mice

Convalescent plasma post-vaccination increases binding and neutralizing antibodies against SARS-CoV-2 variants

Murine hepatitis virus as a surrogate for studying SARS-CoV-2 in food processing biofilms

Development of SARS-CoV-2 detection platform using surface-enhanced Raman spectroscopy

Identification of novel SARS-CoV-2 alpha variant sub-lineage in Europe

Cas13 shines a light on SARS-CoV-2 variants

The influence of SARS-CoV-2 vaccination time on antibody response in healthcare workers

Humoral and cell-mediated immunity six months post BNT162b2 vaccination

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

SARS-CoV-2 variants neutralized by camel nanobodies

SARS-CoV-2 antibodies persisting for nearly a year, including to delta: NZ study

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

The Connection between High-sensitivity Troponin and Heart Attacks

Clinical assay validation for SARS-CoV-2 sequencing using Swift Biosciences amplicon panel

New Canadian serology solution for SARS-CoV-2 infections and vaccination

Breakthrough COVID infections in Northeast Italy showing waning vaccine protection

Panel of broadly neutralizing SARS-CoV-2 nanobodies for immune assay application

N antibodies following SARS-CoV-2 Alpha and Delta infections by vaccination status

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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