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Study identifies two proteins crucial for self-renewal of skin stem cells

Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days.

29 Jul 2016

Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated.

28 Jul 2016

Adhesive patch can deliver triple combination therapy to tumor sites

Approximately one in 20 people will develop colorectal cancer in their lifetime, making it the third-most prevalent form of the disease in the U.S. In Europe, it is the second-most common form of cancer.

25 Jul 2016

Salmonella protein can reduce drug resistant molecule found in cancer cells

A surprising result in an experiment on Salmonella bacteria has led to a discovery that may make drug resistant cancer cells more treatable by conventional chemotherapies.

25 Jul 2016

Combination of two plant compounds holds promise in treating colon cancer

The combination of two plant compounds that have medicinal properties - curcumin and silymarin - holds promise in treating colon cancer, according Saint Louis University research published in the June 23 issue of the Journal of Cancer.

22 Jul 2016

Study uncovers new drug-gene mutation combinations that can kill cancer cells

In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells.

22 Jul 2016

Researchers developing and validating model to predict risk for colon cancer in people under 50

While the incidence of colon cancer has been declining in individuals 50 years old and older in the United States, it is steadily rising in those under age 50. With funding from the U.S. Department of Veterans Affairs, Thomas F. Imperiale, M.D., a VA and Regenstrief Institute clinician-researcher, is developing and validating a model to predict risk for colon cancer in those under 50 with no family history of the disease.

21 Jul 2016

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

A new scientific study has identified why colorectal cancer cells depend on a specific nutrient, and a way to starve them of it. Over one million men and women are living with colorectal cancer in the United States.

21 Jul 2016

Adjuvant chemotherapy may improve survival in stage 2 colon cancer patients

Researchers and physicians have grappled with the role of "adjuvant," or post-surgery, chemotherapy for patients with early-stage colon cancer, even for cancers considered high risk.

15 Jul 2016

Gut microbiota could influence person's likelihood of developing colon cancer

The microscopic organisms that live in our gut do more than help us digest food. A new study in rats bolsters a growing body of evidence that the complex mix of microorganisms found in the gut, known as gut microbiota, could influence a person's likelihood of developing colon cancer.

13 Jul 2016

Fecal transplants may help treat home and hospital-acquired scourge

Fecal transplants are increasingly being used as the treatment of last resort for certain infections in the human gut and have had remarkable success treating the nursing home and hospital-acquired scourge, Clostridium difficile colitis, an infectious diarrhea that often follows antibiotic treatment.

13 Jul 2016

Recellularized colon model helps identify cancer driver genes involved in CRC progression

Genetic mutations are a major cause of cancer, and tracking the role of each gene in cancer pathogenesis has long been an important tool in the fight against a disease that is expected to kill more than 1.6 million people this year.

11 Jul 2016

Research opens up new ways to detect, inhibit cancer spread

Clusters of circulating cells commonly found in the blood of cancer patients have long been the subject of research on cancer. These clusters have been regarded for more than 50 years as malignant cells that have broken off from the primary tumor, spreading cancer to other parts of the body.

8 Jul 2016

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

As the powerhouse of the cells, mitochondria are critical for every organism because of their role in producing energy while also controlling survival, but how they function in cancer is still not completely known.

8 Jul 2016

Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

Ludwig researchers working in collaboration with colleagues in Australia and the US have shown that fragments of tumor DNA circulating in the blood can be used to gauge the risk of colorectal cancer recurrence and the efficacy of chemotherapy following surgery.

7 Jul 2016

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.

7 Jul 2016

New ESMO guidelines reflect personalized approach for management of metastatic colorectal cancer

ESMO, the leading European professional organisation for medical oncology, has released new consensus guidelines for the management of metastatic colorectal cancer that reflect an increasingly personalized approach to treatment, as published online today in Annals of Oncology.

7 Jul 2016

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Scientists at the Johns Hopkins Kimmel Cancer Center and University of Melbourne report they have used a genetic test that spots bits of cancer-related DNA circulating in the blood to accurately predict the likelihood of the disease's return in some — but not all — of a small group of patients with early-stage colon cancer.

7 Jul 2016

Enzyme from fermented Japanese vegetable boosts colon health in rats

An enzyme produced by fermenting a vegetable common in Japanese cuisine may be responsible for increasing the amount of at least one beneficial bacterium associated with healthy colons in a study using rats.

4 Jul 2016

Resistant starch in diet improves balance of gut bacteria, decreases cholesterol

The secret ingredient is in the flour, but its impact lies within the gut. Adding resistant starch to the diets of people with metabolic syndrome can improve bacteria in the gut, according to research from South Dakota State University.

1 Jul 2016

Colon News and Research

Study identifies two proteins crucial for self-renewal of skin stem cells

Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

Adhesive patch can deliver triple combination therapy to tumor sites

Salmonella protein can reduce drug resistant molecule found in cancer cells

Combination of two plant compounds holds promise in treating colon cancer

Study uncovers new drug-gene mutation combinations that can kill cancer cells

Researchers developing and validating model to predict risk for colon cancer in people under 50

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

Adjuvant chemotherapy may improve survival in stage 2 colon cancer patients

Gut microbiota could influence person's likelihood of developing colon cancer

Fecal transplants may help treat home and hospital-acquired scourge

Recellularized colon model helps identify cancer driver genes involved in CRC progression

Research opens up new ways to detect, inhibit cancer spread

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

New ESMO guidelines reflect personalized approach for management of metastatic colorectal cancer

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Enzyme from fermented Japanese vegetable boosts colon health in rats

Resistant starch in diet improves balance of gut bacteria, decreases cholesterol

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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