Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Increased fructose intake during pregnancy can affect metabolism of offspring

An increased level of fructose intake during pregnancy can cause significant changes in maternal metabolic function and milk composition and alter the metabolism of their offspring, researchers from the University of Otago, Wellington, have found.

18 Aug 2020

Diabetes blood markers linked to Alzheimer’s disease pathology, shows study

A new study published in the Journal of Alzheimer's Disease provides insight into the association of blood markers of diabetes with brain beta-amyloid accumulation among older people at risk of dementia.

18 Aug 2020

TGen review: Postmenopausal women at higher risk for developing NALFD

A review article authored by a researcher at the Translational Genomics Research Institute, an affiliate of City of Hope, suggests that following menopause, women are at higher risk for developing nonalcoholic fatty liver disease, a chronic condition caused by the build-up of excess fat in the liver not caused by alcohol.

14 Aug 2020

Diet, not gastric bypass surgery, accounts for improved health

In many studies, bariatric surgery has been highlighted as an almost magical method for weight loss and reversing type 2 diabetes.

13 Aug 2020

Study: High blood sugar may trigger worse outcomes in COVID-19 patients

As COVID-19 continues to rage across the U.S., researchers are digging deeper into how the virus wreaks havoc on the body, especially for those with a pre-existing chronic illness.

12 Aug 2020

First clinical trial could become an effective way to deliver chemotherapy to abdominal cancer patients

City of Hope surgical researchers are the first in the nation to open a clinical trial that could one day become an effective way to deliver chemotherapy to abdominal cancer patients who currently have very few treatment options.

11 Aug 2020

Non-fasting blood test can help accurately identify youth at risk for diabetes and related risks

A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

10 Aug 2020

COVID-19 patient with repeatedly undetectable SARS-CoV-2 antibodies

A recent case study published in the Journal of Applied Laboratory Medicine in August 2020 illustrates this with its finding of persistent seronegativity in a patient confirmed to be SARS-CoV-2 positive.

10 Aug 2020

New approach enhances prediction of type 1 diabetes among susceptible children

A new approach to predicting which babies will develop type 1 diabetes moves a step closer to routine testing for newborns which could avoid life-threatening complications.

7 Aug 2020

Study uncovers sex-specific differences in neural mechanisms for glucose regulation

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have discovered neural mechanisms in mice specific to females that can shift estrogen from playing a protective role in glucose metabolism to one that is disruptive.

6 Aug 2020

Scientists create new mouse model of permanent neonatal diabetes

Diabetes seldom occurs in newborns--a condition known as neonatal diabetes. But when it does, it's mostly due to a mutation in a single gene such as the KCNJ11 or insulin (INS).

6 Aug 2020

Researchers discover how to activate brown fat in humans

The receptor responsible for activating the energy-burning property of brown fat in humans has been identified.

5 Aug 2020

Disruptions to lipid metabolism after childbirth predict future diabetes risk

Scientists have found that disruptions to the metabolism of lipids occur after childbirth in women with gestational diabetes who go on to develop type 2 diabetes.

4 Aug 2020

Applying "temporal pressure" to the skin can help deliver more drugs

Scientists from Nanyang Technological University, Singapore (NTU Singapore) and the Agency for Science, Technology and Research (A*STAR) have showed that applying "temporal pressure" to the skin of mice can create a new way to deliver drugs.

4 Aug 2020

New biomarkers may identify Type 1 diabetes patients who could benefit from immunotherapy

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

3 Aug 2020

Researchers identify differences in clinical features of non-obese patients with NAFLD

Researchers from the University of Tsukuba identify differences in the clinical features of non-obese patients with non-alcoholic fatter liver disease based on their sex and body mass index.

2 Aug 2020

Understanding the causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

31 Jul 2020

Missourians to vote on Medicaid expansion as crisis leaves millions without insurance

Haley Organ thought she had everything figured out. After graduating from a small private college just outside Boston, she earned her master's degree, entered the workforce and eventually landed a corporate job here as a data analyst.

30 Jul 2020

Novel drug candidate offers a major advance in the treatment for diabetes

The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes.

28 Jul 2020

New strategy may help guard beta cells, slow the onset of type 1 diabetes

Type 1 diabetes occurs when a person's own immune system destroys insulin-producing beta cells in the pancreas. In recent years, scientists have learned how to grow large volumes of replacement beta cells, but the researchers are still trying out many options to protect these cells against the immune attack.

27 Jul 2020