Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Cancer drug shows promise for treating rare bleeding disorder

A clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than 1 in 5,000 people worldwide. The trial, led by Keith McCrae, M.D., of Cleveland Clinic and supported by the National Institutes of Health, was stopped early because of these successful findings, and has been published in the New England Journal of Medicine.

19 Sep 2024

New machine learning approach boosts precision of cardiovascular risk assessments

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability.

18 Sep 2024

Clinical trial finds pomalidomide effective for treating rare bleeding disorder

A clinical trial supported by the National Institutes of Health (NIH) was stopped early after researchers found sufficient evidence that a drug used to treat bone marrow cancer and Kaposi sarcoma is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that affects 1 in 5,000 people worldwide.

18 Sep 2024

Study links metal exposure to increased risk of atherosclerosis

Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional risk factors like smoking and diabetes, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

18 Sep 2024

Uncovering the link between pollutants and arrhythmia risk

Arrhythmias, a group of disorders that disrupt the normal rhythm of the heart, can lead to serious health complications such as heart failure, stroke, and sudden death.

18 Sep 2024

Atrial fibrillation affects more Americans than previously estimated

Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5% of the population, or 10.5 million U.S. adults, according to new estimates from UC San Francisco.

11 Sep 2024

Study reveals lower risk of atrial fibrillation after quitting smoking

Quitting cigarettes can significantly lower a person's risk of atrial fibrillation (AFib) compared to those who continue to smoke, according to a study published today in JACC: Clinical Electrophysiology.

11 Sep 2024

COVID-19 mRNA vaccine linked to myocardial scarring in adolescents and young adults

The study investigates COVID-19 vaccine-related myocarditis in adolescents, revealing clinical characteristics and risks of myocardial injury in young adults.

11 Sep 2024

Diligence associated with better cardiovascular outcomes in type 2 diabetes patients

People with type 2 diabetes, who display lower levels of diligence, may have a significantly higher risk of developing cardiovascular disease with which diabetes is strongly associated, finds research published in the open access journal BMJ Open Diabetes Research & Care.

10 Sep 2024

Study finds link between nighttime light exposure and increased Alzheimer's disease risk

Higher nighttime light intensity is correlated with increased Alzheimer's disease prevalence, suggesting light pollution may influence neurodegenerative risks.

10 Sep 2024

Japanese researchers uncover key mechanism protecting heart cells from ischemia

Understanding the mechanisms behind cell death and survival is crucial when it comes to conditions like heart failure, which affects millions of people worldwide.

5 Sep 2024

Many at-home blood pressure monitors may not fit most U.S. adults

At-home blood-pressure monitor cuffs may improperly fit many adults in the U.S., according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2024 and simultaneously published today in the journal Hypertension.

5 Sep 2024

Aficamten improves exercise tolerance in patients with HOCM

Exercise intolerance is often severe among patients with cardiovascular disease and can impose significant limitations on their physical abilities and quality of life. Medications known as cardiac myosin inhibitors (CMIs) are being developed to help patients with hypertrophic obstructive cardiomyopathy (HOCM), a disease in which the heart muscle becomes thickened leading to reduced blood flow out of the heart.

5 Sep 2024

Identifying barriers to effective cardiac rehabilitation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiac rehabilitation (CR) typically consists of physical activity supplemented with lifestyle modifications, including smoking cessation, adherence to a healthy diet, stress management, medication adherence management, risk factor reduction, psychosocial support, and education.

5 Sep 2024

Semaglutide reduced mortality in obese patients by lowering infection-related deaths during COVID-19 pandemic

Semaglutide significantly reduces all-cause mortality in non-diabetic obese patients, particularly by lowering infection-related deaths during the COVID-19 pandemic. However, the study's findings should be interpreted with caution due to potential competing risks and unique pandemic circumstances.

5 Sep 2024

Key insights into cardiac metabolism dysfunction in the elderly

A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 16 on August 19, 2024, entitled, "Cardiac metabolism in the elderly: effects and consequences."

4 Sep 2024

Study uncovers key enzyme link between obesity and atrial fibrillation

A cellular link between obesity and atrial fibrillation -; a heart condition that afflicts over 33 million people worldwide -; presents a promising target for new therapies, researchers from the University of Illinois Chicago report.

4 Sep 2024

Regular mobile phone use linked to increased cardiovascular disease risk in smokers and diabetics

A new study has found that regular mobile phone use was positively associated with incident cardiovascular diseases risk, especially in current smokers and individuals with diabetes. In addition, this association was partly attributed to poor sleep, psychological distress, and neuroticism.

4 Sep 2024

Mineralocorticoid receptor antagonists reduce risk of cardiovascular events in patients with heart failure

MRAs significantly lower the risk of cardiovascular death and HF hospitalization in heart failure patients.

3 Sep 2024

European Society of Cardiology highlights underrecognized link between obesity and heart disease

Obesity is a key factor in cardiovascular disease, prompting the ESC to recommend comprehensive strategies for prevention and management to reduce health risks.

3 Sep 2024

Heart Failure News and Research

Further Reading

Cancer drug shows promise for treating rare bleeding disorder

New machine learning approach boosts precision of cardiovascular risk assessments

Clinical trial finds pomalidomide effective for treating rare bleeding disorder

Study links metal exposure to increased risk of atherosclerosis

Uncovering the link between pollutants and arrhythmia risk

Atrial fibrillation affects more Americans than previously estimated

Study reveals lower risk of atrial fibrillation after quitting smoking

COVID-19 mRNA vaccine linked to myocardial scarring in adolescents and young adults

Diligence associated with better cardiovascular outcomes in type 2 diabetes patients

Study finds link between nighttime light exposure and increased Alzheimer's disease risk

Japanese researchers uncover key mechanism protecting heart cells from ischemia

Many at-home blood pressure monitors may not fit most U.S. adults

Aficamten improves exercise tolerance in patients with HOCM

Identifying barriers to effective cardiac rehabilitation

Semaglutide reduced mortality in obese patients by lowering infection-related deaths during COVID-19 pandemic

Key insights into cardiac metabolism dysfunction in the elderly

Study uncovers key enzyme link between obesity and atrial fibrillation

Regular mobile phone use linked to increased cardiovascular disease risk in smokers and diabetics

Mineralocorticoid receptor antagonists reduce risk of cardiovascular events in patients with heart failure

European Society of Cardiology highlights underrecognized link between obesity and heart disease

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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