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Exploring mouse models for studying liver fibrosis regression

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol abuse, and viral hepatitis.

8 Nov 2024

How bacteria trigger colon cancer

Investigation shows how bacterial adhesins contribute to colon cancer mutations, suggesting new avenues for therapeutic intervention in colorectal cancer.

7 Nov 2024

Study uncovers how certain E. coli bacteria in the gut promote colon cancer

Scientists have uncovered how certain E. coli bacteria in the gut promote colon cancer by binding to intestinal cells and releasing a DNA-damaging toxin.

6 Nov 2024

Saturated fats accelerate neurodegeneration in multiple sclerosis

Targeting ceramide synthase enzymes may reduce multiple sclerosis severity by limiting ceramide C16 synthesis, offering potential neuroprotective strategies.

6 Nov 2024

Lead contamination in South Asian turmeric sparks urgent health concerns

The Biden administration's recently announced plan to replace all lead pipes in the U.S. is a reminder that the toxic metal remains a threat, even in a country that has largely banned its use.

5 Nov 2024

Toddler’s backyard snakebite bills totaled more than a quarter million dollars

This spring, a few days after his 2nd birthday, Brigland Pfeffer was playing with his siblings in their San Diego backyard.

30 Oct 2024

Human midbrain organoids: A promising tool in the fight against Parkinson's disease

Advancements in organoid technology are crucial for Parkinson's disease research, providing human-relevant models for studying disease and testing therapies.

23 Oct 2024

Discovery of new bacterial toxins opens path to novel infection treatments

Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections.

22 Oct 2024

Exploring the role of CPB2 gene in C. perfringens infections

C. perfringens is a widespread bacterium found in the intestines of animals and humans, known for causing severe enteric diseases.

14 Oct 2024

How gut microbiome and fiber diversity shape chronic disease outcomes

Review explores how different types of dietary fibers interact with the gut microbiome, influencing chronic disease risks like obesity, cancer, and cardiometabolic conditions, while emphasizing the need for personalized dietary interventions.

13 Oct 2024

Researchers uncover key bacteria driving success of fecal microbiota transplants

Fecal microbiota transplants, or FMTs, are a magic bullet for patients with recurring infections from Clostridioides difficile (C. diff), but researchers are only beginning to understand why.

9 Oct 2024

Exploring the venomous potential of marine crustaceans for drug development

Many animals use venoms for self-defense or hunting. The components of such venom, known as toxins, interfere with various physiological processes - which is also the reason why they are so interesting for the development of new pharmacological agents.

4 Oct 2024

Phytoene increases lifespan, reduces oxidative stress and amyloid toxicity

Research indicates phytoene from microalgae protects against oxidative stress and beta-amyloid toxicity, suggesting its potential in promoting healthy aging.

30 Sep 2024

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024

Study uncovers decision-making impairments linked to Parkinson's drug

Parkinson's disease (PD), also known simply as Parkinson's, is a disorder of the nervous system that affects millions of people worldwide.

24 Sep 2024

Breakthrough in artificial sugars could revolutionize disease diagnosis and treatment

Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more accurately than ever before.

16 Sep 2024

Breakthrough in understanding formaldehyde toxicity during development and aging

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic Syndrome and Acute Myeloid Leukaemia.

13 Sep 2024

Assessing the environmental impact of biotechnological pesticides

Biotechnological pesticides are a promising alternative to traditional chemical pesticides. But we have limited knowledge of how toxic they are to other organisms in the environment beyond regulatory assessments.

13 Sep 2024

New guidelines for the evaluation and management of chronic constipation

The American Society of Colon and Rectal Surgeons (ASCRS) has issued updated guidelines, published in Diseases of the Colon & Rectum, about how to evaluate and manage chronic constipation. The journal is published in the Lippincott portfolio by Wolters Kluwer.

11 Sep 2024

Combining epidemiology and climate data to uncover the source of an E. coli outbreak

A study published in Eurosurveillance to investigate an outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 in the UK identified contaminated lettuce as the most likely source of the infection and determined that heavy rainfall and flooding may have carried STEC from animal feces to the lettuce crops.

6 Sep 2024