Antibiotic Resistance News and Research

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Evidence from Malawi: Typhoid conjugate vaccine provides protection for up to four years

Study shows that a single dose of typhoid conjugate vaccine provides over four years of protection against typhoid fever in Malawian children, proving effective across all age groups.

31 Jan 2024

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability.

25 Jan 2024

Scientists demonstrate way to produce SARS-CoV-2 receptor protein in mouse cells

A team of scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Columbia University has demonstrated a way to produce large quantities of the receptor that SARS-CoV-2, the virus that causes COVID-19, binds to on the surface of human cells.

22 Jan 2024

Bacteria's "suicidal" immune system boosts antibiotic power against cholera

Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of Tübingen and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.

19 Jan 2024

Understanding antimicrobial resistance in hospital-acquired pneumonia

New research has been published that identifies positive steps towards a better understanding of antimicrobial resistance (AMR), specifically in hospital-acquired pneumonia (HAP).

18 Jan 2024

New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

International research collaboration leads to breakthrough in antibiotic resistance testing using DNA sequencing

The accuracy of antibiotic resistance determination from Enterococcus faecium genomes for diagnostic purposes.

15 Jan 2024

Researchers uncover role of persister cells in antibiotic resistance

Antibiotic overuse can lead to antibiotic resistance, but classic antibiotic resistance might not completely explain why antibiotics sometimes fail.

12 Jan 2024

Superbug spread is not just about antibiotics, new study shows

For the first time, researchers have analyzed the impact of antibiotic use on the rise of treatment-resistant bacteria over the last 20 years in the UK and Norway. They show that while the increase in drug use has amplified the spread of superbugs, it is not the only driver.

11 Jan 2024

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance.

5 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against 'superbugs' such as MRSA, a new study shows.

3 Jan 2024

New family of polymers can kill bacteria without inducing antibiotic resistance

Antibiotic-resistant bacteria have become a rapidly growing threat to public health. Each year, they account for more than 2.8 million infections, according to the U.S. Centers for Disease Control and Prevention.

22 Dec 2023

First new antibiotic class in decades discovered using explainable AI platform

Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning.

20 Dec 2023

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

20 Dec 2023

Hospital coffee machines not responsible for spreading superbugs, study finds

Healthcare workers will be relieved to know that hospital coffee machines are not responsible for spreading disease and a general ban doesn't seem necessary, finds a study published in the Christmas issue of The BMJ.

18 Dec 2023

Poop-based test predicts postoperative infections in liver transplant patients

In a new study, researchers at the University of Chicago were able to predict postoperative infections in liver transplant patients by analyzing molecules in their poop.

15 Dec 2023

New orthopedic implant coating can ward off infection

Superior knee and hip replacements are a step closer after Flinders University and Chinese researchers further test and develop a new orthopedic implant coating which has the strong ability to ward off infection – as well as stimulate bone growth.

5 Dec 2023

Alarming rise in antibiotic-resistant urogenital infections in Greece, study shows escalating resistance trends

The trends in antimicrobial resistance in Greece.

1 Dec 2023

Chlorine-releasing agents in clinical settings fail to combat Clostridioides difficile spores

The current study highlights the resistance of C. difficile spores to chlorine-releasing agents.

29 Nov 2023