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Psychedelic compound shows promise in stress relief for socially aggressive mice

A study in Neuropharmacology reveals that a single dose of the psychedelic compound (R)-DOI significantly improves stress-coping behaviors and reduces inflammatory markers in mice subjected to social aggression.

30 Apr 2024

Fentanyl inhalation linked to irreversible brain damage

Inhaling the synthetic opioid fentanyl may cause potentially irreversible brain damage (toxic leukoencephalopathy), warn doctors in the journal BMJ Case Reports, after treating a middle aged man found unresponsive in his hotel room after snorting the drug.

29 Apr 2024

Formulation and stability evaluation of honey-loaded nanoemulsion for topical delivery

Honey is a viscous, hygroscopic liquid in nature. It has the ability to treat wounds, wrinkles, aging, and inflammation. This study's objective was to create and characterize a nanoemulsion containing honey and evaluate its stability.

29 Apr 2024

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

A low-fiber “Western diet” causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection.

29 Apr 2024

Human mini-lungs mimic animal response to nanomaterials

Human mini-lungs grown by University of Manchester scientists can mimic the response of animals when exposed to certain nanomaterials.

27 Apr 2024

Aspirin's immune-boosting effects in colorectal cancer revealed

Study reveals that aspirin helps the body’s immune system detect and target cancer cells.

27 Apr 2024

PET brain scans could reveal hidden inflammation in patients with multiple sclerosis

A Brigham and Women’s Hospital study of 30 people found that, in patients with MS, advanced brain imaging could identify hidden inflammation not picked up on traditional MRIs

27 Apr 2024

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Parkinson’s UK is investing £2.1million to support Neumora Therapeutics to carry out preclinical testing of NMRA-NLRP3, a NLRP3 inhibitor with the potential to reduce inflammation and protect brain cells in Parkinson’s. NLRP3 is a protein that plays a role in regulating a number of inflammatory processes that are believed to contribute to the damage to brain cells that underlies Parkinson’s.

27 Apr 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

Cinnamon, curcumin, and resveratrol show promise in diabetes inflammation fight

Researchers reviewed the impact of cinnamon, curcumin, and resveratrol on oxidative stress and inflammation in type 2 diabetes patients, highlighting their potential to improve metabolic regulation and reduce complications.

26 Apr 2024

Food additive emulsifiers linked to increased risk of type 2 diabetes

Study found a link between consuming certain food emulsifiers and a higher risk of type 2 diabetes. Emulsifiers are common in processed foods and may disrupt gut health, potentially leading to diabetes.

25 Apr 2024

Diet's impact on gut bacteria offers new clues in Parkinson's disease management

Researchers find that diet significantly influences the gut microbiome in Parkinson's disease patients, potentially affecting disease progression and symptoms.

25 Apr 2024

Scientists identify signaling pathway in liver cells linked to fibrosis

A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured.

25 Apr 2024

Study reveals surprising role of maternal cytokines in offspring psychiatric risk

Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric conditions.

25 Apr 2024

Genetically modified mice reveal key players in immune defense against viruses

Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors.

25 Apr 2024

MIT study reveals circadian impact on drug metabolism in engineered livers

Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.

25 Apr 2024

Imaging using fundus autofluorescence can facilitate the diagnosis and monitoring of rare eye diseases

Uveitis is a rare inflammatory eye disease. Posterior and panuveitis in particular are associated with a poor prognosis and a protracted course of the disease. Diagnosis and monitoring can be challenging for healthcare professionals.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD. It has been known since the 1990s that the two diseases are somehow related.

25 Apr 2024

Inflammation News and Research

Psychedelic compound shows promise in stress relief for socially aggressive mice

Fentanyl inhalation linked to irreversible brain damage

Formulation and stability evaluation of honey-loaded nanoemulsion for topical delivery

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

Human mini-lungs mimic animal response to nanomaterials

Aspirin's immune-boosting effects in colorectal cancer revealed

PET brain scans could reveal hidden inflammation in patients with multiple sclerosis

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Harnessing immune enhancement to combat drug-resistant tuberculosis

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

Cinnamon, curcumin, and resveratrol show promise in diabetes inflammation fight

Food additive emulsifiers linked to increased risk of type 2 diabetes

Diet's impact on gut bacteria offers new clues in Parkinson's disease management

Scientists identify signaling pathway in liver cells linked to fibrosis

Study reveals surprising role of maternal cytokines in offspring psychiatric risk

Genetically modified mice reveal key players in immune defense against viruses

MIT study reveals circadian impact on drug metabolism in engineered livers

Imaging using fundus autofluorescence can facilitate the diagnosis and monitoring of rare eye diseases

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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