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Genetic signature associated with the aging human brain

Unraveling the mysteries of the aging brain is a major goal for brain science, especially given the exploding population of senior citizens and the obvious desire to preserve brain function as long as possible.

9 Jun 2004

Combination treatment may help type 2 diabetes patients

New research presented by Peter Weissman, M.D., from the University of Miami, at the 64th Annual Scientific Sessions of the American Diabetes Association shows that combination treatment with rosiglitazone maleate and metformin significantly improves certain markers of cardiovascular disease risk in patients with type 2 diabetes compared to metformin alone.

6 Jun 2004

New medical patent covering the generation of genetically enhanced therapeutic antigens

Morphotek, Inc. announced today the issuance of United States Patent 6,737,268 covering the generation of genetically enhanced therapeutic antigens.

2 Jun 2004

Women with chest pain who have low hemoglobin levels are more likely to die or suffer a heart attack

Women with chest pain who have low hemoglobin levels are more likely to die or suffer a heart attack, heart failure, stroke or other cardiovascular event than women with normal hemoglobin levels, according to a new study in the June 2, 2004 issue of the Journal of the American College of Cardiology.

2 Jun 2004

Human Genome Sciences has begun dosing patients with chronic hep C drug

Human Genome Sciences, Inc. announced today that it has begun dosing patients in a Phase 2 clinical trial of Albuferon™ (albumin-interferon alpha) in patients with chronic hepatitis C who are naïve to interferon-alpha treatments.

27 May 2004

Pregnant female asthmatics who eat oily fish may be helping to protect their children against developing asthma

Pregnant female asthmatics who eat oily fish, such as salmon or trout, may be helping to protect their children against developing asthma, according to a study presented at the American Thoracic Society International Conference in Orlando on May 25.

25 May 2004

Antioxidant compound found in green tea leaves does not clear established plaque

Using a technique that enables them to study both early and advanced stages of arterial plaque buildup in the same mice, researchers at Cedars-Sinai Medical Center found that an antioxidant compound found in green tea leaves does not clear established plaque but does inhibit the development of new deposits.

24 May 2004

Moderate exercise in conjunction with common dietary supplements significantly reduce the risk of atherosclerosis

Moderate exercise in conjunction with common dietary supplements significantly reduce the risk of atherosclerosis because, combined, they boost the body’s production of nitric oxide, which protects against a variety of cardio-vascular disorders, a new UCLA study led by 1998 Nobel Laureate in medicine Louis J. Ignarro shows.

24 May 2004

Trial shows Daclizumab therapy improves multiple sclerosis outcome

A small clinical trial of patients with multiple sclerosis (MS) who did not respond to interferon alone found that adding the human antibody daclizumab improved patient outcome. Patients who received the combined therapy had a 78 percent reduction in new brain lesions and a 70 percent reduction in total lesions, along with other significant clinical improvements.

24 May 2004

Cystic Fibrosis Foundation Therapeutics awards $21 million to Vertex

Vertex Pharmaceuticals Incorporated has announced that it has expanded its drug discovery and development collaboration with Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation.

24 May 2004

Once-daily treatment with Alvesco (ciclesonide) in asthma patients has no effect on normal adrenal function

New data presented at the American Thoracic Society’s 2004 International Conference show that once-daily treatment with the investigational therapy Alvesco (ciclesonide) in mild-to-moderate asthma patients has no effect on normal adrenal function, as demonstrated by measurements of the hypothalamic-pituitary-adrenal (HPA)-axis.

24 May 2004

Using gene therapy to fight rheumatoid arthritis

Guided by a similar principle, arthritis researchers at the University of Florida and Harvard University hope to use gene therapy to help joint cells pump out a harmless protein that parks in receptor sites, leaving a notorious inflammatory agent “circling the lot” and unable to cause pain, swelling and possible joint damage.

21 May 2004

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Researchers in the department of ophthalmology at the University of Arizona College of Medicine in Tucson played an important role in the development of Restasis, the first alternative to artificial tears for the treatment of dry eye syndrome.

21 May 2004

Watching for West Nile virus, dead bird and mosquito monitoring resumes

Warmer spring weather and the coming mosquito season has the Department of Health on the lookout for West Nile virus again, working with local health departments to identify mosquitoes, track dead birds and monitor any human illness across Washington. This season brings mosquito-breeding weather and the threat of mosquito-borne disease, including West Nile virus.

20 May 2004

Causes of hepatitis and potential therapies that may improve care presented in study

Hepatitis, a potentially serious disease caused by a virus that attacks the liver, is a major problem worldwide. Hepatitis A is generally food-borne, while hepatitis B and C spread primarily through parenteral or sexual routes. Hepatitis B and C can be life-long, potentially deadly chronic infections.

19 May 2004

Accurate and effective new methods for diagnosis of Inflammatory bowel diseases

Inflammatory bowel diseases collectively cause significant lifestyle sacrifices and suffering and millions of dollars in related health care costs every year, partially due to a lack of effective diagnostic procedures and therapies. In new studies presented today at Digestive Disease Week in New Orleans, researchers show evidence of accurate and effective new methods for diagnosis, as well as improved treatment options, for sufferers of ulcerative colitis and Crohn’s diseases.

19 May 2004

Anti-clotting treatment underused at many hospitals

Academic hospitals are more likely than community or Veteran’s Administration (VA) hospitals to follow national guidelines for treating patients at risk for blood clots with aspirin or warfarin.

19 May 2004

Fatty liver disease (NAFLD) in obese children has distinct characteristics different from those found in adults

Potentially life-threatening non-alcoholic fatty liver disease (NAFLD) in obese children has distinct characteristics, often different from those found in adults, according to a University of California, San Diego (UCSD) School of Medicine study led by Jeffrey Schwimmer, M.D., assistant professor of pediatrics.

19 May 2004

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Centocor, Inc., and Schering-Plough Corporation announced today the initiation of the SONIC (Study of Immunomodulator Naive patients in Crohn's Disease) trial that will evaluate the efficacy of REMICADE® (infliximab) versus azathioprine, a conventional immunosuppressive agent, alone and versus the combination of both drugs for the treatment of patients with Crohn's disease.

18 May 2004

Higher rate of cardiac complications from smallpox vaccinations for US military

While adverse reactions from smallpox vaccinations given to military personnel in the wake of renewed threats of bioterrorism remain minimal, the rate of cardiac complications has been higher than expected, according to a clinical review presented at an American Medical Society media briefing on cardiology today.

16 May 2004

Inflammation News and Research

Genetic signature associated with the aging human brain

Combination treatment may help type 2 diabetes patients

New medical patent covering the generation of genetically enhanced therapeutic antigens

Women with chest pain who have low hemoglobin levels are more likely to die or suffer a heart attack

Human Genome Sciences has begun dosing patients with chronic hep C drug

Pregnant female asthmatics who eat oily fish may be helping to protect their children against developing asthma

Antioxidant compound found in green tea leaves does not clear established plaque

Moderate exercise in conjunction with common dietary supplements significantly reduce the risk of atherosclerosis

Trial shows Daclizumab therapy improves multiple sclerosis outcome

Cystic Fibrosis Foundation Therapeutics awards $21 million to Vertex

Once-daily treatment with Alvesco (ciclesonide) in asthma patients has no effect on normal adrenal function

Using gene therapy to fight rheumatoid arthritis

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Watching for West Nile virus, dead bird and mosquito monitoring resumes

Causes of hepatitis and potential therapies that may improve care presented in study

Accurate and effective new methods for diagnosis of Inflammatory bowel diseases

Anti-clotting treatment underused at many hospitals

Fatty liver disease (NAFLD) in obese children has distinct characteristics different from those found in adults

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Higher rate of cardiac complications from smallpox vaccinations for US military

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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